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  • Deciphering RNA Secondary Structure
    ... Le Grice. "Approaches such as this will contribute toward developing RNA-based therapeutics against HIV." Novel RNA Modeling Delineating the secondary structure of large, ...
    10-15-2013
  • Growing and Preparing Adult Stem Cells
    ... including fibroblasts and lymphocytes, as well as the development of iPSC-based experimental systems for in vitro modeling of human disease and development. | Josh P. Roberts
    10-15-2013
  • 3 Win Nobel Chemistry Prize for Computer Modeling Used in Drug...
    of Isaac Newton with quantum physics in modeling processes that involve chemical reaction. ... This facilitated the first consistent modeling of the catalytic effect of an enzyme. "We ...
    10-9-2013
  • Advice to iPSC Banks: Share, Ensure Quality, Manage Immune Matching
    Experts in the emerging field of iPSC banking urge action on several fronts to ensure that iPSCs realize their full potential for improved drug screening, disease modeling, and ...
    10-4-2013
  • Snag-Free Induction of Pluripotency in Adult Cells
    ... in somatic cells, including fibroblasts and lymphocytes, as well as the development of iPSC-based experimental systems for in vitro modeling of human disease and development. ...
    9-18-2013
  • 3D High-Content Analysis of Spheroids
    There is increasing evidence that 3D cell culture models are more physiologically relevant than traditional 2D cell cultures, particularly in the context of in vitro tumor modeling...
    9-15-2013
  • New Report Lays Out Guidelines to Improve Cancer Care
    ... with multiple comorbidities is so great that it justifies modeling this program in drugs used to treat older adults with cancer and individuals with multiple comorbidities." ...
    9-10-2013
  • Manipulating Methodologies for Reprogramming Cells
    ... By using experimental and modeling approaches to integrate these findings, Dr. Feinberg and his colleagues revealed that the defining epigenetic trait in cancer is not so much the ...
    9-1-2013
  • Life Science Superstars 40 and Under
    networks from functional genomics data and predicting and modeling protein structure. ... time-lapse movies, and mathematical modeling to study gene circuit architecture and ...
    8-21-2013
  • Seattle BioMed Wins $16.6M Grant to Tackle Tuberculosis
    research is done, making a move from a 'trial and error' approach to predictive modeling," said Alan Aderem, Ph.D., president of Seattle BioMed, in a statement. "By drawing ...
    8-15-2013
  • High School Whiz Kids Win Scientific Prestige . . . and Big Bucks
    ... disease. "I like how interdisciplinary mathematical modeling can be," she said. "Its basis may be in mathematics and/or physics, yet it can be used to solve real-world problems." ...
    8-1-2013
  • Crown Bioscience Acquires U.K. CRO Precos
    organization, giving Crown Bioscience clients access to Precos' unique and growing panel of patient-derived xenograft, orthotopic, and metastatic modeling and imaging services." ...
    7-29-2013
  • Downstream Process Bottlenecks
    Single-use equipment, in-line buffer dilution, high-capacity chromatography resins, and a deeper appreciation for modeling and scheduling software, have helped to mitigate some of ...
    7-1-2013
  • Assay Development Driving Personalized Medicine
    ... Accounting for Variability Biomarker analysis is a common practice in pharmacokinetic/pharmacodynamics (PK/PD) modeling to learn about a drug's mechanism of action. Biomarker ...
    7-1-2013
  • Reducing the Cost of Peptide Synthesis
    ... Polypeptide Group is increasingly using modeling to predict, design, and assess synthetic processes. The company has developed an in silico method that allows them to input a ...
    7-1-2013
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    Journal Articles

  • Modeling and Managing Experimental Data Using FuGE
    Andrew R. Jones, Allyson L. Lister, Leandro Hermida, Peter Wilkinson, Martin Eisenacher, Khalid Belhajjame, Frank Gibson, Phil Lord, Matthew Pocock, Heiko Rosenfelder, Javier Santoyo-Lopez, Anil Wipat, Norman W. Paton
    OMICS: A Journal of Integrative Biology
    Modeling and Managing Experimental Data Using FuGE OMICS: A Journal of Integrative Biology ... and efficiency of experimental data modeling in the life sciences, and it has been ...
  • Modeling of Wildlife-Associated Zoonoses: Applications and Caveats
    Stephen Eubank, J K Blackburn, Kathleen Anne Alexander, Bryan Lewis, Madhav Marathe
    Vector-Borne and Zoonotic Diseases
    Modeling of Wildlife-Associated Zoonoses: Applications and Caveats Vector-Borne and ... How do modeling frameworks differ and what considerations are important when applying ...
  • Modeling Regulatory Networks at Virginia Tech
    Marc T. Vass, Layne T. Watson, Jason W. Zwolak, Nicholas A. Allen, Laurence Calzone, Katherine C. Chen, Andrea Ciliberto, Naren Ramakrishnan, Clifford A. Shaffer, Jill C. Sible, John J. Tyson
    OMICS: A Journal of Integrative Biology
    Modeling Regulatory Networks at Virginia Tech OMICS: A Journal of Integrative Biology The ... to create effective software tools for modeling gene-protein-metabolite networks, to ...
  • Modeling Inhalational Tularemia: Deliberate Release and Public...
    Joseph R. Egan, Ian M. Hall, Steve Leach
    Biosecurity and Bioterrorism: Biodefense Strategy, Practice, and Science
    Modeling Inhalational Tularemia: Deliberate Release and Public Health Response Biosecurity and Bioterrorism: Biodefense Strategy, Practice, and Science Two epidemic modeling ...

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