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  • Seasoned Drugs Offer Therapeutic Gold Mine
    ... chairman for department of systems medicine and bioengineering at the Methodist Hospital Research Institute, and director of the NCI Center for Modeling Cancer Development. Dr. ...
    5-15-2013
  • Highlights from AACR
    The platform can be used to develop and validate cell lines for target identification and validation, and for assay development, disease modeling, and compound profiling. Active ...
    5-15-2013
  • Harnessing the Power of Kinase Inhibitors
    ... In Silico Chemistry Modeling Amedeo Caflisch, Ph.D., who runs a computational structural biology lab at the University of Zurich, along with his colleagues developed an in silico ...
    5-8-2013
  • Stem Cell Model of Neurodegenerative Disease Elucidates Potential...
    disease-in-a-dish modeling of a rare genetic disorder, ataxia telangiectasia (A-T). ... (iPSCs) to advance disease-in-a-dish modeling of a rare genetic disorder, ataxia ...
    5-7-2013
  • Parexel Acquires Heron Group in Up To $38M Deal
    Heron expertise and methodologies span a range of services that include strategic market access planning, systematic reviews, economic modeling and evaluation, pricing, ...
    5-1-2013
  • Exposing the Exposome
    ... to model future behavior and predict response to therapy, the integration and modeling represent, at this time, some of the main challenges in the emerging field of ...
    5-1-2013
  • Separation of Therapeutic Biomolecules
    Mixed-Mode Chromatography, Layered Bead Designs, In Silico Modeling Used at Large Scale ... Leveraging Predictive Modeling Tools Marcel Ottens, Ph.D., assistant professor, Delft ...
    5-1-2013
  • Human iPSC-Derived Hepatocytes
    Functional Model Tissue for In Vitro Predictive Metabolism, Toxicity, and Disease Modeling ... interest to areas of environmental toxicology, disease modeling, and drug development. ...
    5-1-2013
  • Comparative Genomics: Insights into Disease Susceptibility
    ... Further delving into the functional annotation, protein structure modeling, epigenetics, and association studies, they have identified and annotated candidate variants to develop a ...
    5-1-2013
  • Stockholm-Uppsala Region Ups the Ante
    ... Serendipity has been operating since 2004, and has established more than 10 companies, including BinaryBio, which provides solutions for protein modeling, protein structure ...
    4-15-2013
  • Fighting Cancer in 3D
    ... Their research appears online this week in the Proceedings of the National Academy of Sciences in a paper titled "Modeling Ewing sarcoma tumors in vitro with 3D scaffolds". What ...
    4-3-2013
  • Computational Bio Problem Solving
    A number of techniques are utilized, such as genomics, mathematical modeling and simulation, and designing biological databases. [wavebreakmedia/Shutterstock] We are clearly on the ...
    4-1-2013
  • Predicting Drug Toxicity in Humans
    In vitro and in silico modeling of tissues and diseases using lab-on-a-chip technologies are available. As agencies such as the NIH, FDA, and the DARPA seek new ideas and ...
    4-1-2013
  • Advertorial: 3-D Tumor Spheroids in Extracellular Matrix: Old...
    ... Tumor cell spheroids also represent an opportunity to evaluate processes and modulators of cancer cell dissemination from the tumor, modeling early metastatic events. Using the ...
    4-1-2013
  • Predictive Cancer Modeling Consortium Has New Member
    receive €1.2 million (roughly $1.55 million) in funding under the French Government's "Investing for the Future" program. Predictive Cancer Modeling Consortium Has New Member
    3-25-2013
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    Journal Articles

  • Modeling Tissue Growth Within Nonwoven Scaffolds Pores
    Sharon L. Edwards, Jeffrey S. Church, David L.J. Alexander, Stephen J. Russell, Eileen Ingham, John A.M. Ramshaw, Jerome A. Werkmeister
    Tissue Engineering, Part C: Methods
    Modeling Tissue Growth Within Nonwoven Scaffolds Pores Tissue Engineering, Part C: Methods In this study we present a novel approach for predicting tissue growth within the pores ...
  • Spatially Explicit West Nile Virus Risk Modeling in Santa Clara...
    Sarah K. Konrad, Scott N. Miller, Will K. Reeves, Noor S. Tietze
    Vector-Borne and Zoonotic Diseases
    Spatially Explicit West Nile Virus Risk Modeling in Santa Clara County, California Vector-Borne and Zoonotic Diseases Abstract A geographic information system model designed to ...
  • Diminished Insulin Resistance with Weight Loss in Severely Overweight...
    James N. Roemmich, Emily Y. Liu, Alan D. Rogol, Leonard H. Epstein, Teresa Quattrin
    Metabolic Syndrome and Related Disorders
    The relationship between child and parent weight change supports the role of the parent in modeling appropriate weight loss behaviors and restructuring the environment so that ...
  • Mutations in Streptococcus pneumoniae Penicillin-Binding Protein...
    Patrick Maurer, Katya Todorova, Julia Sauerbier, Regine Hakenbeck
    Microbial Drug Resistance
    In contrast, in silico modeling revealed that they affect van der Waal's interactions with the PASTA1 (PBP and Serine/Threonine Kinase Associated) domain of the C-terminal ...

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