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Search Results - Mitochondrial Diseases
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  • Using TALENs to Edit Mitochondrial Genes
    Scientists have developed a new approach to eliminate mutated DNA inside mitochondria that they say could be used to treat a variety of mitochondrial diseases, including the ...
    8-5-2013
  • More Than a Messenger: A New Class of Drugs-mRNA-Based Therapeutics
    ... prophylactic vaccination for infectious diseases, and a recent proof-of-concept study in ... potently activated by bacterial and mitochondrial RNA, but not by mammalian total RNA, ...
    6-14-2013
  • Stem Cell Science Advances
    ... Mitalipov's lab studies mitochondrial DNA, which as part of the cytoplasmic compartment ... People will make patient-specific models for brain diseases, for hepatic metabolism, for ...
    6-11-2013
  • ReGen Med: Straight Out of Mythology
    promises are particularly important for diseases that have therapeutic options that are ... In a chemical screen that proposed to identify inhibitors of the mitochondrial FAD-linked ...
    6-11-2013
  • Seasoned Drugs Offer Therapeutic Gold Mine
    ... It can also analyze the relevance of all drugs against diseases of interest. "COSS ... of MS. COSS found an unknown role of mitochondrial dysfunction in MS, which previously ...
    5-15-2013
  • Mass Spec Provides Peek into PTMs
    ... The applicability of this method has been tested with individual proteins, mitochondrial ... of diabetes and the related diabetic cardiovascular diseases," Dr. Ma concludes. ...
    5-15-2013
  • Comparative Genomics: Insights into Disease Susceptibility
    Of the 7,098 complete mitochondrial genomes, researchers identified 6,110 single ... Rhesus macaques ( Macaca mulatta ) are proven models for the study of diseases such as ...
    5-1-2013
  • Predicting Drug Toxicity in Humans
    ... Kwok. Exploring Mitochondrial Function Mitochondrial bioenergetic balance may be a ... Mitochondria are central to drug development as targets in CNS diseases, cancer, and ...
    4-1-2013
  • Edison Will Receive Up To $525M in Mitochondrial and CNS Disease...
    The initial scope of the transaction includes both pediatric orphan inherited mitochondrial and adult central nervous system diseases. Edison's translational platform is based on ...
    3-28-2013
  • Hope for Autism Lies in Century-Old Drug
    of medicine and co-director of the Mitochondrial and Metabolic Disease Center at the ... for almost a century to treat other diseases to block the 'danger' signal in a mouse ...
    3-14-2013
  • Nucleic Acid Sample Preparation in MDx
    ... enriching for highly similar sequences known as NUMTs (nuclear mitochondrial sequences). ... microbiology-gene sequencing, infectious diseases, Quest Diagnostics Nichols Institute, ...
    3-1-2013
  • Ten Predictions that Will Transform Healthcare
    (NYSCF) Laboratory and Columbia University Medical Center (CUMC) developed a technique that holds potential for preventing children from inheriting mitochondrial diseases. ...
    2-15-2013
  • Designer Babies Debate Heats Up
    that safely eliminate the risk of these diseases. She raised the question, what distances will women afflicted by mitochondrial disease travel to safeguard their children? ...
    2-14-2013
  • 10 Predictions That Will Transform Healthcare
    (NYSCF) Laboratory and Columbia University Medical Center (CUMC) developed a technique that holds potential for preventing children from inheriting mitochondrial diseases. ...
    1-17-2013
  • Novel Applications for Systems Biology
    ... They've overexpressed each of 250 genes known to be important in mitochondrial dysfunction ... research could shed some light on human diseases as well, possibly even explaining ...
    12-1-2012
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    Journal Articles

  • First Record of Stegomyia albopicta in Turkey Determined By Active...
    Kerem Oter, Filiz Gunay, Erkut Tuzer, Yvonne-Marie Linton, Romeo Bellini, Bulent Alten
    Vector-Borne and Zoonotic Diseases
    DNA Barcoding Vector-Borne and Zoonotic Diseases Despite its confirmed establishment in ... DNA barcodes (658 bp of the mitochondrial cytochrome c oxidase I (COI) gene) were compared ...
  • Regulation and Physiologic Functions of GTPases in Mitochondrial...
    Naotada Ishihara, Hidenori Otera, Toshihiko Oka, Katsuyoshi Mihara
    Antioxidants & Redox Signaling
    The regulation of mitochondrial dynamics coupled with a quality control system is ... Defects of these mechanisms cause various disorders, including neurodegenerative diseases ...
  • Mitochondrial Uncoupling Proteins in the Central Nervous System
    Jeong Sook Kim-Han, Laura L. Dugan
    Antioxidants & Redox Signaling
    flux from mitochondria by physiologically modulating mitochondrial membrane potential. ... intriguing proteins in acute and chronic diseases of the nervous system will be discussed. ...
  • Molecular Evidence Indicates That Phlebotomus major sensu lato...
    Koray Ergunay, Ozge Erisoz Kasap, Zeliha Kocak Tufan, Mahur H. Turan, Aykut Ozkul, Bulent Alten
    Vector-Borne and Zoonotic Diseases
    Vector-Borne and Zoonotic Diseases Abstract Sandfly fever turkey virus (SFTV) is a ... a multiplexed PCR targeting the mitochondrial cytochrome b gene of various vertebrates. ...

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