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  • Newly Found Protein Modification May Play a Role in Cancer and...
    ... consequent buildup of certain glucose metabolites in the processing pathway. He and Dr. Cravatt suspect that these overabundant metabolites may end up being shunted into other ...
    8-2-2013
  • Making Sense of Small Molecules
    The field of metabolomics-the study of small-molecule metabolites-seeks to fill those ... The single-draw blood test pairs an evaluation of three metabolites with an algorithm to ...
    8-1-2013
  • Closer-to-Real 3D Cell Culture Advances
    ... They were also maintained after two weeks of culture and allowed identification of drug metabolites comparable to that seen in vivo. Wayne Pacelle, president of HSUS, said in ...
    7-3-2013
  • Improving Molecular Distribution Analysis
    The main benefit of MSI compared to traditional methods is the technology's possibility to create distribution images for any number of compounds and metabolites from a single ...
    7-1-2013
  • Targeting Deranged Metabolism to Treat Cancer
    Normally, IDH catalyzes the conversion of isocitrate to α-ketoglutarate (α-KG), both metabolites ultimately derived from glucose in the course of cellular respiration. Alpha-KG ...
    7-1-2013
  • Metabolomics-Young Field, Bright Future
    and Applications ($ Millions) Metabolites have been used as biomarkers for decades. ... This attention to metabolites is resulting in a growing number of biomarkers that is ...
    6-25-2013
  • Metagenomics May Hold Key to Novel Antibiotic Discovery
    ... potential to provide access to novel metabolites with modes of action that differ from ... could identify novel bioactive secondary metabolites from otherwise-silent gene clusters. ...
    6-4-2013
  • Patent Eligibility of Biological Methods and Compositions
    ... step as "simply...[telling] the doctor to determine the level of the relevant metabolites in the blood, through whatever process the doctor or the laboratory wishes to use," ...
    6-3-2013
  • Getting Creative with Mass Spec
    ... have been able to separate morphine from its metabolites such as morphine glucuronide. ... other low-level clinical studies for metabolites and drug-related material are poised to ...
    6-1-2013
  • Deciphering the Mysteries in Lipid Biology
    metabolites in plasma. They stand out because of their structural diversity and the sheer number of molecular species. In-depth analysis by the consortium called LIPID Metabolites ...
    6-1-2013
  • Targeting Deranged Metabolism to Treat Cancer
    Normally, IDH catalyzes the conversion of isocitrate to α-ketoglutarate (α-KG), both metabolites ultimately derived from glucose in the course of cellular respiration. Alpha-KG ...
    5-30-2013
  • Monsanto Seed Wars Sprout Controversy
    ... Mayo's test measured the same metabolites as Prometheus', but the former used different levels to determine toxicity of the two metabolites. Limited Reach Though the high court has ...
    5-29-2013
  • Flexibility in Biopharmaceutical Manufacturing Capacity
    ... This system also continuously removes metabolites during cell culture. Both cell culture processes and product quality, several studies have shown, are comparable in single-use ...
    5-28-2013
  • Metabolomics Study Points to Biomarkers Predictive of Mortality...
    day 28 differentially expressed 59 metabolites, compared with survivors. Dr. Rogers and her team later found that 34 of those metabolites were associated with death in a second ...
    5-17-2013
  • Mass Spec Provides Peek into PTMs
    ... been utilized to spatially profile proteins, lipids, drug, and small molecule metabolites in tissues, but it has not been previously applied to N-linked glycan analysis. ...
    5-15-2013
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    Journal Articles

  • Incidence of Hydromorphone-Induced Neuroexcitation in Hospice...
    Justin Kullgren, Vy Le, Warren Wheeler
    Journal of Palliative Medicine
    Hydromorphone and morphine share a similar phase two metabolism and both have metabolites that can accumulate and potentially cause the rare adverse effect of opioid-induced ...
  • Multi-omics Approach for Estimating Metabolic Networks Using...
    Mitsunori Kayano, Seiya Imoto, Rui Yamaguchi, Satoru Miyano
    Journal of Computational Biology
    for these analyses is a set of multi-omics data for RNA, proteins, and metabolites. ... In addition, in the real data analysis, we investigated the role of metabolites and ...
  • Fermentation Metabolites from Lactobacillus gasseri and Propionibacter...
    Yuko Kato-Mori, Takenori Orihashi, Yuta Kanai, Michiko Sato, Kenji Sera, Katsuro Hagiwara
    Journal of Medicinal Food
    Fermentation Metabolites from Lactobacillus gasseri and Propionibacterium freudenreichii Exert Bacteriocidal Effects in Mice Journal of Medicinal Food
  • Evaluation of Normalization Methods to Pave the Way Towards Large...
    Bedilu Alamirie Ejigu, Dirk Valkenborg, Geert Baggerman, Manu Vanaerschot, Erwin Witters, Jean-Claude Dujardin, Tomasz Burzykowski, Maya Berg
    OMICS: A Journal of Integrative Biology
    This normalization method allows to remove the systematic variability between two measurement blocks over time and maintains the differential metabolites. In conclusion, ...

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