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  • New International Collaboration Aims to Develop Drugs, Diagnostics...
    Under the terms of the agreement, Wi2 will provide access to technologies related to cancer, neurodegenerative diseases, and metabolic diseases, and will organize and finance a ...
    5-2-2013
  • Merck Launches Up To $430M Diabetes Collaboration with Abide
    Abide Therapeutics to discover, develop, and commercialize small molecule therapies designed to treat type 2 diabetes and other metabolic diseases by targeting serine hydrolases. ...
    5-2-2013
  • Twin Effort Hones In on Membrane Proteins
    They could help in the search for therapies for cancer and infectious, neurodegenerative, metabolic, genetic, and other diseases. However, only about 2% of membrane proteins have ...
    5-1-2013
  • Human iPSC-Derived Hepatocytes
    ... Figure 2. iCell Hepatocytes are sensitive to aflatoxin-B1, demonstrating metabolic ... Hepatitis viral infections, both HCV and HBV, remain common diseases in both the ...
    5-1-2013
  • Hormone Holds Promise for Replacing Insulin Injections
    ... partnerships with top-tier pharmaceutical and biotechnology companies in key therapeutic areas that include neuroscience, pain, metabolic diseases, oncology, and inflammation. ...
    4-26-2013
  • GEN | Biolinks
    ... Pharmaceuticals Drugs for Neglected Diseases Initiative DSM Duke University Duquesne ... Inc Mersana Therapeutics, Inc Metabolex, Inc Metabolic Solutions Development Co. ...
  • Merck & Co. Picks Up Exclusive Option on Xenon CV Drugs
    ... presentation of common diseases. In addition to CV disorders, other medical areas of focus for the company include pain, anemia, and metabolic disease. Licensing decision ...
    4-17-2013
  • Yale Wins $10 Million Grant for Novel Immunobiology Research
    paradigm shift in the science of chronic diseases and may lead to new prevention ... sugar, sleep patterns, and a host of metabolic processes needed for fitness and survival. ...
    4-9-2013
  • Agios Lays the Foundation on New Cancer Metabolism Programs
    Agios is focused on discovering and developing drugs in the fields of cancer metabolism and rare metabolic genetic diseases. Foundation Medicine's molecular information platform ...
    4-4-2013
  • Predicting Drug Toxicity in Humans
    ... Mitochondria are central to drug development as targets in CNS diseases, cancer, and metabolic diseases and as one of the main off-target sites causing undesirable side effects and ...
    4-1-2013
  • AstraZeneca, Moderna in Up to $420M+ mRNA Drug Development Deal
    AstraZeneca will use Moderna Therapeutics' messenger RNA technology to develop and commercialize new drugs for cancer and "serious" cardiovascular, metabolic, and renal diseases, ...
    3-21-2013
  • AstraZeneca Idling Another 2,300; Unveils Comeback Strategy
    ... It agreed to license Moderna Therapeutics' messenger RNA technology to develop and commercialize new drugs for cancer and "serious" cardiovascular, metabolic, and renal diseases ...
    3-21-2013
  • Hope for Autism Lies in Century-Old Drug
    Metabolic Disease Center at the University of California, San Diego School of Medicine. "We used a class of drugs that has been around for almost a century to treat other diseases ...
    3-14-2013
  • Spectrum to Develop Ligand's PG-Free Melphalan
    Injection, and the folate analog metabolic inhibitor Folotyn® (pralatrexate ... medical needs of patients for a range of diseases including idiopathic thrombocytopenic ...
    3-14-2013
  • Receptos Licenses AbbVie Antibody for Co-Development
    Financial terms were not disclosed. Receptos, a San Diego developer of drugs for immune and metabolic diseases, said it plans to conduct a Phase II study intended to demonstrate ...
    3-13-2013
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    Journal Articles

  • Anthropometric Measurements and Diabetes Mellitus: Clues to the...
    Harold E. Bays, Kathleen M. Fox, Susan Grandy
    Metabolic Syndrome and Related Disorders
    Abstract Background: Increased visceral adipose tissue (VAT) is "pathogenic" through adverse endocrine and immune contributions to metabolic diseases such as diabetes mellitus, ...
  • Prevalence of Metabolic Syndrome in Pakistan
    Abdul Basit, A. Samad Shera
    Metabolic Syndrome and Related Disorders
    Lifestyle-related risk factors are associated with the metabolic syndrome and diabetes. ... and nationwide surveillance and prevention programs against noncommunicable diseases.
  • Mouse Mesenchymal Stem Cells Suppress Antigen-Specific TH Cell...
    Tobias V. Lanz, Christiane A. Opitz, Peggy P. Ho, Ankur Agrawal, Christian Lutz, Michael Weller, Andrew L. Mellor, Lawrence Steinman, Wolfgang Wick, Michael Platten
    Stem Cells and Development
    diseases, such as experimental autoimmune encephalomyelitis (EAE). Tryptophan (trp) catabolism by indolamine-2,3-dioxygenase 1 (IDO1) is a chief endogenous metabolic ...
  • Transplantation of Human Adipose Tissue-Derived Multilineage...
    Hanayuki Okura, Ayami Saga, Yuichi Fumimoto, Mayumi Soeda, Mariko Moriyama, Hiroyuki Moriyama, Koji Nagai, Chun-Man Lee, Shizuya Yamashita, Akihiro Ichinose, Takao Hayakawa, Akifumi Matsuyama
    Tissue Engineering, Part C: Methods
    serum cholesterol in the WHHL rabbits. These results suggested that hADMPC transplantation could correct the metabolic defects and be a novel therapy for inherited liver diseases.

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