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Search Results - Membrane Proteins
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  • Newly Found Protein Modification May Play a Role in Cancer and...
    ... membrane compartments. "It appears that wherever GAPDH goes within cells, it is capable of catalyzing the localized production of 1,3-BPG, which in turn reacts with nearby proteins ...
    8-2-2013
  • Hematologic Diagnostics Go with the Flow
    ... proteins that are normally found only on the inside of the granular membrane. When the granules open, proteins like LAMP1 (CD107a), which are normally on the inner surface of ...
    8-1-2013
  • Molecular Imaging Driving Development
    Labeling of antibodies, antibody-drug conjugates, proteins and peptides, and nanoparticles ... circuitry to create transient nanopores by electroporation of the membrane patch. ...
    8-1-2013
  • Removing the Receptor Deconvolution Bottleneck
    The elegance of the Retrogenix microarray system lies in expressing full-length human membrane proteins in the context of human cells. This allows for normal trafficking of the ...
    8-1-2013
  • Membrane Protein Monoclonal Antibodies
    Global sales of therapeutic antibodies reached $38 billion in 2009, and the market continues to grow. Transmembrane proteins, including multipass membrane proteins (MMP) like ...
    8-1-2013
  • Downstream Process Bottlenecks
    ... the use of smaller columns, more efficient filtration, and membrane chromatography. Manufacturers of non-mAb proteins still face challenges, Bach says, because the molecular ...
    7-1-2013
  • Production of Routine and Difficult Targets
    ... The target proteins are the bacterial polytopic membrane proteins EnvZ, PheP, and YidC; the human polytopic membrane proteins Tetraspanin (Tsp) A and B; the soluble proteins ...
    7-1-2013
  • Literature Review: A Snapshot Taken from the Inside
    ... The labeling was exceptionally specific and distinguished between inner membrane proteins facing the matrix versus the intermembrane space (IMS). Several proteins previously ...
    6-26-2013
  • The 11 Golden Rules of Working with Proteomic Samples
    ... samples and extract proteins for analysis. Enzymatic activity will resume in frozen samples once thawed, resulting in further change especially since membrane integrity may have ...
    6-21-2013
  • Exploring Exosomal RNA
    Tiny, subcellular membrane-bound vesicles called exosomes are periodically released by a wide variety of cell types, carrying along with them proteins, microRNA (miRNA), and ...
    6-15-2013
  • Liquid Handling Needs a Helping Hand
    ... Hart's high-throughput Expression of Soluble Proteins by Random Incremental Truncation ... The contents of the plates are then arrayed onto a membrane, and the plate is frozen down. ...
    6-15-2013
  • Nudging Difficult-to-Express Proteins Along
    Overcoming toxicity and poor accumulation are common themes in many unsuccessful attempts to overexpress difficult proteins such as multispanning membrane proteins. According to ...
    6-15-2013
  • Stem Cell Science Advances
    The cytoplasmic metaphase factors chew up the nuclear membrane and condense the chromatin ... act like flags to recruit additional proteins-some of which are signals to turn a gene ...
    6-11-2013
  • ReGen Med: Straight Out of Mythology
    ... which had been converted to a plasma membrane-binding format, are selected based on ... and bioprocessing of recombinant proteins and monoclonal antibodies, we envision ...
    6-11-2013
  • Improving Proteomics Approaches
    ... The ones who remain need much more efficient ways to characterize and purify proteins. ... Life Raft? Membrane-bound biomolecules present numerous challenges for analysis and ...
    5-15-2013
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    Journal Articles

  • Exploring the Contribution of Efflux on the Resistance to Fluoroquinol...
    Sunita Paltansing, Anouk Y. Tengeler, Margriet E.M. Kraakman, Eric C.J. Claas, Alexandra T. Bernards
    Microbial Drug Resistance
    The objective was to investigate the contribution of active efflux and expression of outer membrane proteins in a collection of clinical E. coli isolates collected at a clinical ...
  • Regulation and Physiologic Functions of GTPases in Mitochondrial...
    Naotada Ishihara, Hidenori Otera, Toshihiko Oka, Katsuyoshi Mihara
    Antioxidants & Redox Signaling
    Antioxidants & Redox Signaling Significance: Mitochondria are double membrane-bound ... types of high molecular-weight GTPase proteins have been identified as core components ...
  • Mitochondrial Uncoupling Proteins in the Central Nervous System
    Jeong Sook Kim-Han, Laura L. Dugan
    Antioxidants & Redox Signaling
    proteins (UCPs), a subfamily of the mitochondrial transporter family, are related by sequence homology to UCP1. This protein, which is located in the inner mitochondrial membrane, ...
  • Redox Signaling in Plants
    Christine H. Foyer, Graham Noctor
    Antioxidants & Redox Signaling
    The respective roles of ROS, low molecular antioxidants, redox-active proteins and ... cells such as that across the plasma membrane facilitates flexible and multiple ...

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