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  • Ovarian Cancer Treatment Options Multiply
    ... The M.D. Anderson Cancer Centers in Houston and Orlando are performing the trial for solid, inoperable tumors, including ovarian, lung, colon, pancreatic, liver melanoma, head and ...
    10-8-2013
  • FDA Speeds Things Up
    people with advanced melanoma. According to trial investigator Omid Hamid, M.D., chief, translational research and immunotherapy and director, Melanoma Therapeutics at the ...
    10-1-2013
  • NCI Re-Ups BioMarker Strategies' SBIR Award for Melanoma CDx
    diagnostic test to facilitate the selection of optimal therapy for patients with melanoma. ... Initial tumor types included melanoma and breast cancer. The $1.5 million second phase of ...
    9-25-2013
  • Takeover Targets: Who Is First on the List?
    ... to Novartis (Phase II); INCB24360 for metastatic melanoma and ovarian cancer (both Phase II); and INCB39110 for myelofibrosis, rheumatoid arthritis, and psoriasis (all Phase I/II). ...
    9-24-2013
  • Striking Solid Tumors: Transporting Treatments Safely and Effectively
    risk of one type of skin cancer-invasive melanoma-from 1/600 in 1960 to 1/50 in 2008. The treatment of solid tumors remains an outstanding obstacle for the healthcare community. ...
    9-23-2013
  • Cutting Melanoma Off at the Pass
    by which melanoma can evolve resistance to a combination of BRAF and MEK inhibitors. ... MEK2-Q60P mutation and BRAF gain in a melanoma from a patient who progressed on the MEK ...
    9-20-2013
  • Harvard's Wyss Institute, Charité Partner on Tissue Engineering...
    Phase I clinical trial of a novel implantable vaccine-which uses a small disk-like sponge about the size of a fingernail that is made from FDA-approved polymers-to treat melanoma. ...
    9-17-2013
  • Gene Test Boom Faces Lawsuits
    ... endometrial, gastric, ovarian, pancreatic, uterine, and melanoma), at an average selling prioce of $3,700. The other new tests are myPath Melanoma(tm) and myPlan Lung Cancer(tm). ...
    9-15-2013
  • Roche Signs Up to $422.5M Collaboration with Inovio
    A Phase I study combining the drug candidate with Zelboraf (vemurafenib) in patients with previously untreated BRAFV600-mutation-positive metastatic melanoma. A Phase I study ...
    9-10-2013
  • New Sponge-Based Therapeutic Cancer Vaccine Begins Human Clinicals
    that they started a Phase I clinical trial of an implantable vaccine to treat melanoma. ... have otherwise died from melanoma within about 25 days-showed complete tumor regression. ...
    9-6-2013
  • FDA Speeds Things Up
    melanoma. "It's never a good time to be a patient," commented trial investigator Omid Hamid, M.D., chief, Translational Research and Immunotherapy and director, Melanoma ...
    9-3-2013
  • Gene Test Boom Faces Lawsuits
    ... endometrial, gastric, ovarian, pancreatic, uterine, and melanoma), at an average selling price of $3,700. The other new tests are myPath Melanoma(tm) and myPlan Lung Cancer(tm). ...
    8-16-2013
  • Vical Scraps Melanoma Candidate After Phase III Failure
    (velimogene aliplasmid) for metastatic melanoma after the investigational intratumoral ... ONCEPT®, designed to aid in extending the survival time of dogs with oral melanoma. ...
    8-12-2013
  • Altered Receptor Allows Tumors to Sneak by Immune System
    Using mouse models of breast cancer and melanoma, they show that loss of the Type III TGF-β receptor (TGFBR3) in tumors promotes cancer progression by altering signaling in ...
    8-9-2013
  • Ovarian Cancer Treatment Milestone Earns Array BioPharma $5M
    Novartis recently detailed plans to initiate Phase III trials of MEK162 in both NRAS- and BRAF-mutant melanoma. All three trials will be conducted as part of the Novartis/Array ...
    7-2-2013
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    Journal Articles

  • Efficient Melanoma Cell Killing and Reduced Melanoma Growth in...
    Lothar F. Fecker, Stefanie Rückert, Bahtier M. Kurbanov, Magdalena Schmude, Eggert Stockfleth, Henry Fechner, Jürgen Eberle
    Human Gene Therapy and Part B: Methods
    Efficient Melanoma Cell Killing and Reduced Melanoma Growth in Mice by a Selective Replicating Adenovirus Armed with Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Human ...
  • Malignant Melanoma Therapy by Chemotherapy and Autoimmunity Induced...
    Shi Jin, QingYuan Zhang, Xinmei Kang, JingXuan Wang, WenZhou Sun
    Cancer Biotherapy and Radiopharmaceuticals
    Malignant Melanoma Therapy by Chemotherapy and Autoimmunity Induced by Cytokine Cancer ... factor (GM-CSF) with interleukin-2 (IL-2) in patients with advanced malignant melanoma. ...
  • Murine B16 Melanoma Vaccination-Induced Tumor Immunity: Identification...
    Tzu Y. Wu, W. Robert Fleischmann
    Journal of Interferon & Cytokine Research
    Murine B16 Melanoma Vaccination-Induced Tumor Immunity: Identification of Specific Immune ... Journal of Interferon & Cytokine Research Vaccination using inactivated B16 melanoma cells ...
  • Correlation Between Melanoma Angiogenesis and the Mesenchymal...
    Baocun Sun, Shiwu Zhang, Chunsheng Ni, Danfang Zhang, Yanxue Liu, Wenzhi Zhang, Xiulan Zhao, Chunhua Zhao, Mingxia Shi
    Stem Cells and Development
    Correlation Between Melanoma Angiogenesis and the Mesenchymal Stem Cells and Endothelial ... mice engrafted with human malignant melanoma, human cells incorporated into tumor vessels. ...

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