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Search Results - Liver Diseases
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  • Antisense Drugs Finally Turning the Corner
    million-plus partnership designed to develop new therapies for neurological diseases. ... Diamond pointed out that GHr is expressed in the liver, which is an ideal target tissue ...
    10-15-2013
  • Roche Signs Up to $422.5M Collaboration with Inovio
    ... of target cells without evidence of liver injury. "We are very excited to have this ... added Janet Hammond, head of Roche's infectious diseases discovery and translational area. ...
    9-10-2013
  • How Anthrax Kills
    The investigators, from the National Institute of Allergy and Infectious Diseases and the ... cells and muscle cells surrounding blood vessels, and edema toxin targeting liver cells. ...
    8-29-2013
  • CIRM Approves $40.6M in Early Translational Research Grants
    in prostate cancer, heart disease, liver disease, autism, and HIV/AIDS. The ... studies for treating some of the worst diseases we have in the community," CIRM ...
    8-29-2013
  • Intravenous Vaccine Proves Protective against Malaria
    Institute of Allergy and Infectious Diseases (NIAID) reported the results of a Phase ... induced a higher frequency of liver-resident CD8+ T cells specific for PfSPZ ...
    8-8-2013
  • Unraveling the Transcriptome
    ... personal transcriptome profiling in cancer and other diseases," Dr. Gerstein says. ... Liver RNA from rats exposed to Aflatoxin B1 was analyzed by RNA-Seq or microarray: Reads ...
    7-1-2013
  • Exploring Exosomal RNA
    ... exosomal miRNA pathway using a liver cancer donor and receptor cell-line system, she said. ... and therapeutics for cancer and other diseases, Life Technologies is in the process of ...
    6-15-2013
  • Lilly Halts Phase II Study of Alzheimer's Candidate
    to monitor all participants with abnormal liver biochemical tests, and further evaluate ... and developing medicines for devastating diseases like Alzheimer's is fraught with many ...
    6-14-2013
  • Aphios, VivaCell to Develop Cannabinoid-Based Drugs for MS, CNS...
    sclerosis and other neurodegenerative diseases such as Huntington's, Parkinson's, and ... bypass first-round metabolism in the liver, improve safety, and increase therapeutic ...
    6-12-2013
  • ReGen Med: Straight Out of Mythology
    And Prometheus, whose liver regenerated overnight, often prompts questions on whether ... promises are particularly important for diseases that have therapeutic options that are ...
    6-11-2013
  • Deciphering the Mysteries in Lipid Biology
    ... in genes encoding sterol metabolic enzymes lead to serious liver and endocrine problems. ... Simultaneously, the team is evaluating samples from patients with clearly defined diseases...
    6-1-2013
  • Synthetic Sea Anemone Toxin Could Be Newest Weapon in Obesity...
    arthritis, and other autoimmune diseases, may also be of use for the treatment of ... weight gain, white fat deposits, fatty liver, blood cholesterol and blood sugar by ...
    5-28-2013
  • Softening the Blow from FOLFOX Treatment
    ... for magnetic resonance imaging in the liver: When injected too rapidly, patients' ... PledPharma sees potential to use PLED-derivative compounds against several diseases, and ...
    5-15-2013
  • Biotechs Need to Walk the Walk on Drug Value
    ... mathematical model of drug-induced liver injury, among new preclinical tools ... The firm is also evaluating opportunities for PLED substances in other diseases related to ...
    5-15-2013
  • Human iPSC-Derived Hepatocytes
    ... Hepatitis viral infections, both HCV and HBV, remain common diseases in both the developing and developed worlds. These infections can lead to liver damage manifesting as fibrotic ...
    5-1-2013
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    Journal Articles

  • Evaluation of Angiotensinogen c.1-44G>A and p.M268T Variants...
    Juliane Halangk, Thomas Berg, Konrad Neumann, Christoph Sarrazin, Holger Hinrichsen, Carolin Fitz, Gero Puhl, Tobias Mueller, Peter Neuhaus, Bertram Wiedenmann, Heiko Witt
    Genetic Testing and Molecular Biomarkers
    Evaluation of Angiotensinogen c.1-44G>A and p.M268T Variants as Risk Factors for Fibrosis Progression in Chronic Hepatitis C and Liver Diseases of Various Etiologies Genetic ...
  • The Zebrafish as a Model to Study Polycystic Liver Disease
    Pamela S. Tietz Bogert, Bing Q. Huang, Sergio A. Gradilone, Tetyana V. Masyuk, Gary L. Moulder, Stephen C. Ekker, Nicholas F. LaRusso
    Zebrafish
    The Zebrafish as a Model to Study Polycystic Liver Disease Zebrafish In the polycystic liver diseases (PLD), genetic defects initiate the formation of cysts in the liver and ...
  • Engraftment Potential of Spheroid-Forming Hepatic Endoderm Derived...
    Sung-Eun Kim, Su Yeon An, Dong-Hun Woo, Jiyou Han, Jong Hyun Kim, Yu Jin Jang, Jeong Sang Son, Hyunwon Yang, Yong-Pil Cheon, Jong-Hoon Kim
    Stem Cells and Development
    Stem Cells and Development Transplantation and drug discovery programs for liver diseases are hampered by the shortage of donor tissue. While recent studies have shown that hepatic ...
  • Modified Infusion Procedures Affect Recombinant Adeno-Associated...
    Kazuo Ohashi, Hiroyuki Nakai, Linda B. Couto, Mark A. Kay
    Human Gene Therapy and Part B: Methods
    Recombinant adeno-associated virus (rAAV) vectors have therapeutic potential for the treatment of several types of liver diseases including hepato-deficiency disorders. Most of the ...

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