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Search Results - LentiVector

  • Scientists Identify Therapy-Resistant Subset of Tumor-Propagating...
    ... The researchers moved on to carry out experiments using lentivector-expressing LAPC9 and LAPC4 xengraft tumors. PSA -lo cells from these tumors were, like the LNCaP cells, ...
    5-7-2012
  • Oxford BioMedica and Mayo Clinic Partner to Develop Gene Therapy...
    Oxford BioMedica maintains its LentiVector technology can stably deliver genes into cells ... The firm's lead in-house LentiVector-based product, ProSavin(tm), is in Phase I/II ...
    10-31-2011
  • Researchers Suggest Role for Hypothalamic PPAR-Gamma in Diabetes...
    ... The same attenuating effect on weight gain and overeating was achieved by injecting the hypothalamus of rosiglitazone-treated rats with a lentivector-based shRNA to block PPAR-γ ...
    5-2-2011
  • Oxford BioMedica Buys Manufacturing Facility from RecipharmCobra...
    and full Phase II studies with its LentiVector-based ProSavin® gene therapy for ... The sanofi-aventis partnership includes development of four LentiVector-based ocular ...
    1-31-2011
  • Sanofi-Aventis Shutters 13 Clinical Programs, Gains Four from...
    The collaboration to exploit its LentiVector gene delivery technology in the development ... The ophthalmology collaboration initially covers four of Oxford BioMedica's LentiVector-ba...
    4-29-2009
  • S. Korean Gov't Nudges Biotech Along
    ... ethanol producers), the Bioinformatics Research Center, and the LentiVector Institute, which develops lentiviral vector systems for gene delivery both in vivo and in vitro. ...
    2-15-2009
  • Biopartnering Crucial to Survival in Europe
    ... Revenue is being generated by alliances such as that signed recently with Sigma Aldrich (www.sigmaaldrich.com) for the commercialization of Oxford Biomedica's LentiVector, a ...
    1-1-2006
  • BIO-Europe Conference Gauges Future
    ... The company also has a program in Parkinson's disease and other neurological conditions using LentiVector, a technology for delivering genes to the nervous system. ProSavin, a ...
    1-15-2005
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    Journal Articles

  • Autologous Transplantation of Lentivector/Acid Ceramidase-Transduced...
    Jagdeep S. Walia, Anton Neschadim, Orlay Lopez-Perez, Abdulfatah Alayoubi, Xin Fan, Stéphane Carpentier, Melissa Madden, Chyan-Jang Lee, Fred Cheung, David A. Jaffray, Thierry Levade, J. Andrea McCart, Jeffrey A. Medin, Stephane Carpentier
    Human Gene Therapy and Part B: Methods
    Autologous Transplantation of Lentivector/Acid Ceramidase-Transduced Hematopoietic Cells in Nonhuman Primates Human Gene Therapy and Part B: Methods Abstract Farber disease is a ...
  • Targeting Lentiviral Vectors to Antigen-Specific Immunoglobulins
    Leslie Ziegler, Lili Yang, Kye il Joo, Haiguang Yang, David Baltimore, Pin Wang
    Human Gene Therapy and Part B: Methods
    Tumor suppression was observed in vivo, using the engineered lentivector to deliver a suicide gene to a xenografted tumor expressing aCD20. These results show the feasibility of ...
  • Controllable Expansion of Primary Cardiomyocytes by Reversible...
    Yue Zhang, Edem Nuglozeh, Fatouma Touré, Ann Marie Schmidt, Gordana Vunjak-Novakovic
    Human Gene Therapy and Part B: Methods
    We explored the feasibility of enabling the in vitro expansion of primary neonatal rat cardiomyocytes by lentivector-mediated cell immortalization, and then reverting the phenotype ...
  • Single-Chain Antibodies That Target Lentiviral Vectors to MHC...
    Francesca Gennari, Luciene Lopes, Els Verhoeyen, Wayne Marasco, Mary K. Collins
    Human Gene Therapy and Part B: Methods
    To improve the safety and efficacy of lentivector vaccination, we sought to target vector transduction to antigen-presenting cells by modifying the viral envelope. To do this we ...

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