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Search Results - Kidney Diseases
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  • Addressing Unmet Medical Needs with Complex Carbohydrate Chemistry
    disease pathologies including cancer, cardiovascular disease, and inflammatory diseases. ... such as heart disease, stroke, kidney damage, retinopathy, and diabetic foot. ...
    2-28-2013
  • Slaying the Fungus Among Us
    ... of patients suffer from some form of kidney poisoning; 15% of patients on AmB in a 1999 study (Wingard, et. al., Clinical Infectious Diseases) were forced into kidney dialysis. ...
    11-14-2012
  • Functional and Mature Kidney Tissue Generated
    The technology will also prove valuable for research into the causes and mechanisms of complex kidney diseases and provide tissues for screening potential drug compounds. The ...
    10-19-2012
  • AstraZeneca Licenses Sodium Overload Inhibitor
    absorption of dietary sodium, and divert sodium excretion from the kidney to the feces. ... of NHE3 inhibitors for other diseases resulting from sodium and fluid overload. ...
    10-9-2012
  • Going to the Dogs
    ... Variations of the gene for the protein folliculin are involved in kidney cancer and skin .../NEJMra1204453 Clues to cancer and other diseases emerge from the genome of man's best ...
    8-16-2012
  • Fewer Approvals and Filings Sully FDA Offensive
    ... distress syndrome), and Voraxaze (toxic methotrexate levels due to kidney failure). ... a shift toward drugs for chronic diseases; and stricter review standards that ...
    7-18-2012
  • TGen Isolation Method May Help Diagnose Kidney Disease
    to renal biopsy, urine is an ideal source of biomarkers, particularly for diseases of the kidney and urinary tract because it can be conveniently collected in large amounts ...
    7-11-2012
  • Genkyotex Raises $26M for Diabetic Nephropathy Drug
    NOX4 plays a key role in glomerular damage and kidney fibrosis, which lead to albuminuria ... of indications, including other fibrotic diseases, including atherosclerosis, idiopathic ...
    7-9-2012
  • NGS & RNA-Seq Form Dynamic Duo
    ... isolation of CTCs or other cells from breast exudates (breast cancer), urine (kidney-related diseases), and feces (colorectal cancers), etc. "The high sensitivity and specificity ...
    7-1-2012
  • Immune Mouse that Fully Recapitulates Individual Human Immune...
    Research into the genetic basis of human immune diseases has to date largely been limited ... cells seeded into fetal human thymus grafts transplanted in the animal's kidney capsule. ...
    3-15-2012
  • Protein Kinase Identified as Therapeutic Target for Kidney Disease
    identified HIPK2 upregulation in damaged mouse kidneys, and went on to confirm that increased levels of the protein are present in human patients with various kidney diseases. ...
    3-12-2012
  • Retrophin Takes on Ligand's Nephropathy Candidate DARA for $1M...
    may help patients who are at a high risk of losing their kidneys to their diseases by delaying the progression and reversing severe markers of kidney damage such as proteinuria. ...
    2-21-2012
  • Evotec, Harvard, and Brigham & Women's Partner on Kidney Diseases
    The work will focus particularly on identifying disease-modifying mechanisms involved in kidney diseases. Evotec claims the multidisciplinary efforts will provide both new insights ...
    1-17-2012
  • Protein Folding and Disease: The Path from Bench to Bedside
    ... "Protein misfolding or aggregation is a component of diseases that "span virtually every therapeutic area, from eye, to kidney, metabolic, heart, and neurodegenerative diseases." ...
    1-15-2012
  • Akebia Spins out Aerpio to Develop Tie-2 Activators and HIF-1a...
    its small molecule Tie-2 activator and HIF-1α stabilizer programs for multiple diseases. ... A Phase IIa dose-ranging trial evaluating AKB-6548 in stage 3 and 4 chronic kidney disease ...
    1-9-2012
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    Journal Articles

  • Field and Laboratory Evaluation of Diagnostic Assays for Detecting...
    Kerry A. Padgett, Barbara Cahoon-Young, Ryan Carney, Leslie Woods, Deryck Read, Stan Husted, Vicki Kramer
    Vector-Borne and Zoonotic Diseases
    Wild Birds Vector-Borne and Zoonotic Diseases Three diagnostic assays for detecting ... Oral swabs and kidney tissue in VTM tested by RT-PCR were found to have similar accuracy ...
  • Molecular Pathways and Crosstalk Characterizing the Cardiorenal...
    Irmgard Mühlberger, Konrad Mönks, Raul Fechete, Gert Mayer, Rainer Oberbauer, Bernd Mayer, Paul Perco
    OMICS: A Journal of Integrative Biology
    Abstract The risk of developing cardiovascular diseases (CVD) is dramatically increased in patients with chronic kidney diseases (CKD). Mechanisms leading to this cardiorenal ...
  • Ex Vivo Expansion and In Vivo Infusion of Bone Marrow-Derived...
    Lihui Liu, Zhao Sun, Bin Chen, Qin Han, Lianmin Liao, Mingyue Jia, Ying Cao, Jie Ma, Qiyun Sun, Mei Guo, Zeyuan Liu, Huisheng Ai, Robert Chunhua Zhao
    Stem Cells and Development
    in tissue engineering and immune diseases, we designed a preclinical and Phase I ... Laboratory tests for blood, bone marrow, kidney, and liver function were conducted and no ...
  • Laparoscopic Nephroureterectomy for Tuberculous Nonfunctioning...
    Percy Jal Chibber, Hemendran N. Shah, Pritesh Jain
    Journal of Laparoendoscopic& Advanced Surgical Techniquesand Part B, Videoscopy
    Nephroureterectomy for Other Diseases Journal of Laparoendoscopic& Advanced ... LNU for tuberculous ureteric stricture with a nonfunctioning kidney at our center. ...

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