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Search Results - Isomerase

  • NeuroVive, Isomerase Team Up to Study Cyclophilin Inhibitor
    NeuroVive Pharmaceutical has signed a collaboration agreement with Isomerase Therapeutics ... management spun out Isomerase, which will join NeuroVive in studying the portfolio . ...
    6-13-2013
  • Disulfide-Bonded Protein Production in E. coli
    Involvement of Disulfide Bond Isomerase Improves Protein Folding Disulfide bonds are an ... Protein disulfide isomerase (PDI) carries out dsb oxidation and isomerization in the ER of ...
    2-1-2012
  • Next-Generation DNA Assembly Tools
    II centromere; trp1, gene encoding yeast's phosphoribosylanthranilate isomerase; oriT, F' origin of transference; COS, bacteriophage lambda cos site. (B) YAC conversion cassette. ...
    10-15-2010
  • Cell Therapeutics to Appeal FDA Decision on Pixantrone NDA
    ... of agents, according to CTI. Similar to anthracyclines, pixantrone inhibits Topo-isomerase II. But unlike anthracyclines, rather than intercalation with DNA, pixantrone ...
    9-14-2010
  • CTI Cuts Workforce after Receiving a Complete Response Letter...
    of agents, according to CTI. Similar to anthracyclines, pixantrone inhibits topo-isomerase II. Unlike anthracyclines, though, rather than intercalation with DNA, Pixuvri ...
    4-16-2010
  • FDA Requires More Clinical Work to Give Cell Therapeutics' NHL...
    ... of agents, according to CTI. Similar to anthracyclines, pixantrone inhibits topo-isomerase II. Unlike anthracyclines, though, rather than intercalation with DNA, pixantrone ...
    4-9-2010
  • Protein Expression Poised for Reinvention
    ... Many proteins have been analyzed including lysozyme, Factor XIII, Con A, insulin, and glucose isomerase. "Over 50 percent of targeted proteins in structural genomics programs ...
    10-1-2009
  • Alternative Feedstocks Boost Ethanol Production
    ... Stephen Hughes, Ph.D., research molecular biologist at the USDA-ARS, described an automated process for high-throughput transformation (with bacterial xylose isomerase and xylose ...
    6-15-2009
  • Investigators Suggest that an Alzheimer's Mouse Model Is Invalid
    Researchers found that the Pin1 (prolyl isomerase) enzyme, which has been implicated in Alzheimer's, has two distinct effects depending on the tau protein. They thus suggest that ...
    4-23-2008
  • Industrial Biotech Meets Systems Biology
    ... Metabolic engineering using systems biology tools revealed, however, that introduction of key enzymes (xylose reductase, xylitol dehydrogenase, xylulokinase, or xylose isomerase) ...
    1-1-2007
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    Journal Articles

  • Engineered Pathways for Correct Disulfide Bond Oxidation
    Guoping Ren, James C.A. Bardwell
    Antioxidants & Redox Signaling
    DsbB and CpxR that alter the redox environment of the periplasm and increases the level of the chaperone/protease DegP, allowing DsbA to gain disulfide isomerase ability in vivo. ...
  • In Vivo Reduction-Oxidation State of Protein Disulfide Isomerase...
    Christian Appenzeller-Herzog, Lars Ellgaard
    Antioxidants & Redox Signaling
    In Vivo Reduction-Oxidation State of Protein Disulfide Isomerase: The Two Active Sites Independently Occur in the Reduced and Oxidized Forms Antioxidants & Redox Signaling
  • Redox-Regulated Peptide Transfer from the Transporter Associated...
    Kwangmin Cho, Sunglim Cho, Seong-Ok Lee, Changhoon Oh, Kwonyoon Kang, Jeongmin Ryoo, Sungwook Lee, Seongman Kang, Kwangseog Ahn
    Antioxidants & Redox Signaling
    Class I Molecules by Protein Disulfide Isomerase Antioxidants & Redox Signaling Most ... In this study, we investigated the possible role of protein disulfide isomerase (PDI) as a ...
  • How Proteins Form Disulfide Bonds
    Matthieu Depuydt, Joris Messens, Jean-Francois Collet
    Antioxidants & Redox Signaling
    Abstract The identification of protein disulfide isomerase, almost 50 years ago, opened ... reticulum (protein disulfide isomerase and Ero1), and the mitochondrial ...

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