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  • Twin Effort Hones In on Membrane Proteins
    ... Synthelis specializes in making fully functional membrane proteins, including ion channels, porins, and G-protein coupled receptors from humans, animals, bacteria, viruses, and ...
    5-1-2013
  • Steric Exclusion Chromatography
    Examples include ion-exchange chromatography, where solid-phase charges interact ... method are that PEG is virus-stabilizing, and flow-through monolith channels is laminar. ...
    3-15-2013
  • Isolating Membrane Protein Antibodies
    Company Promotes Use of Phage Display with Lipoparticles to Isolate Human Antibodies Integral membrane proteins such as GPCRs, ion channels, and transporters are a large family of ...
    3-15-2013
  • Focusing on Multi-Analyte Detection & Analysis
    ... samples for 15 different indications. "The challenges faced with the technology are membrane proteins such as receptors and ion channels. Those can be tricky proteins to produce. ...
    12-1-2012
  • Deal Struck for Nanobodies Targeting Ion Channels
    and antagonistic functional Nanobodies against both voltage-gated and ligand-gated ion channels. "Due to the formatting flexibility of Nanobodies, we are able to combine ...
    10-2-2012
  • Advertorial: Essen BioScience
    a renowned global Discovery Services team, Essen BioScience provides quantitative assay solutions in an array of research areas including oncology, neuroscience, and ion channels. ...
    10-1-2012
  • Antibody Labeling Turns Stressful
    StressMarq offers a range of purified proteins as western blot controls and activity assays, along with a range of antibodies targeting cellular stress and ion channels and ...
    9-26-2012
  • Merck Pulls Plug on Cardiome Partnership
    Vernakalant IV is not approved for use in the U.S. or Canada. Vernakalant works by selectively blocking multiple ion channels in the heart that are known to be active during ...
    9-26-2012
  • Acquisitions Grow Corning's Product Line
    ... Types of Epic assays include small-molecule binding, functional protease, kinase, protein-protein interactions, G-protein coupled receptors, viral detection, and ion channels. ...
    9-15-2012
  • Someone's in the Kitchen With DNA: A Biotech Thanksgiving
    With a little more engineering, enhanced fluorescent proteins found their way from jellyfish and coral into organisms the world over. Light-sensitive ion channels and pumps from ...
    9-4-2012
  • Calixar, Synthelis Offer Membrane Protein Services
    Synthelis specializes in the production of fully functional membrane proteins, including ion channels, porins, and GPCRs from plants, animals, bacteria, and viruses. Its production ...
    7-5-2012
  • Zealand Pharma, Protagonist to Develop Disulfide-Rich Peptide...
    virtually any specified target including those traditionally addressed by mAbs or targets such as GPCRs, ion channels, and chemokines that are generally intractable to mAbs. ...
    6-18-2012
  • Mass Spec Gives Shot in Arm to Proteomic Analysis
    ... The column with the best outcomes was coupled with different ionization sources. The ion ... and microflow by interchanging the flow channels in our 2D nanoLC systems, such as the ...
    6-15-2012
  • SPR Solutions for Interaction Analysis
    ... As many essential biological functions involve the participation of membrane proteins such as GPCRs, ion channels, and membrane-bound enzymes, they constitute a significant ...
    6-15-2012
  • High-Throughput Alanine Scanning
    The human proteome consists of >5,000 membrane proteins, including an estimated 901 GPCRs, 488 transporters, and 237 ion channels, which transmit key information to the interior of ...
    6-15-2012
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    Journal Articles

  • Genetic Variation in Taste and Its Influence on Food Selection
    Bibiana Garcia-Bailo, Clare Toguri, Karen M. Eny, Ahmed El-Sohemy
    OMICS: A Journal of Integrative Biology
    with sweet and umami taste perception, the ion channels PKD1L3 and PKD2L1 linked to sour taste, and the integral membrane protein CD36, which is a putative "fat taste" receptor. ...
  • Non-Cardiomyocytes Influence the Electrophysiological Maturation...
    Changsung Kim, Maryam Majdi, Peng Xia, Karen A. Wei, Maria Talantova, Sean Spiering, Brandon Nelson, Mark Mercola, Huei-sheng Vincent Chen
    Stem Cells and Development
    Sarcolemmal ion channels evolved later upon further differentiation within EBs and played an increasing role in controlling automaticity and electrophysiological properties of ...
  • Antinociceptive Effect of Riluzole in Rats with Neuropathic Spinal...
    Aldric Hama, Jacqueline Sagen
    Journal of Neurotrauma
    Neuropathic pain in rat models of SCI is thought to be mediated by dysfunctional ion channels and glutamate receptors expressed on CNS neurons. Thus riluzole's mechanism of action ...
  • Compression Induces Acute Demyelination and Potassium Channel...
    Hui Ouyang, Wenjing Sun, Yan Fu, Jianming Li, Ji-Xin Cheng, Eric Nauman, Riyi Shi
    Journal of Neurotrauma
    Immunofluorescence imaging and coherent anti-Stokes Raman spectroscopy (CARS) were used to visualize key pathological changes to ion channels and myelin. Compression caused ...

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