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  • Advertorial: Agilent Technologies
    platform: A 12-point serial dilution of insulin (n=8 per point dilution) was processed ... The mass of the insulin in the elution was plotted against the mass of the insulin in the ...
    5-15-2013
  • ATMI Supplies Bioreactor for Orgenesis, Takes $1.3M Stake
    cells are converted into functioning insulin-producing cells, the companies said today. ... The system is designed to produce a sufficient amount of autologous insulin-producing ...
    5-9-2013
  • Biologically Relevant Laminins
    ... cells that are crucial for the insulin production and proliferation of beta cells. ... For example, although pancreatic beta cells can be kept in culture and produce insulin, ...
    5-1-2013
  • Merck Joins Pfizer to Develop Type 2 Diabetes Drug
    However, Forxiga was approved for use in combination with insulin and other treatments for type 2 diabetes-except in patients who cannot tolerate metformin, who can use Forxiga as ...
    4-29-2013
  • Hormone Holds Promise for Replacing Insulin Injections
    the pancreatic beta cells that produced insulin in the mouse model, thus serving as a key ... That expression correlated with beta cell proliferation in other mouse models of insulin ...
    4-26-2013
  • Biosimilars: 10 Drugs to Watch
    ... the generic version of insulin analog Humalog (Eli Lilly) Glargine: Biocon and Mylan on February 14 announced a strategic collaboration to develop a biosimilar to the insulin ...
    4-22-2013
  • Boosting Downstream Productivity
    ... A good illustration can be found in the recombinant insulin purification process, where HPLC is the only cost-effective solution to allow separation of several isoforms of the ...
    4-15-2013
  • Axe Falls on 1,000 at Lilly
    ... insulin manufacturing operations, on top of a $140 million expansion of those operations disclosed in November. Lilly said its latest expansion would entail adding a second insulin ...
    4-12-2013
  • Fighting Cancer in 3D
    culture, but also exhibited remarkable differences in the expression pattern of the insulin-like growth factor-1 receptor/mammalian target of rapamycin pathway. 2D cultures may ...
    4-3-2013
  • Lilly Plans to Add $180 Million Insulin Manufacturing Investment
    insulin manufacturing operations. This is in addition to the company's November 2012 announcement of a $140 million expansion of insulin manufacturing activities. ...
    4-2-2013
  • AstraZeneca Idling Another 2,300; Unveils Comeback Strategy
    ... sold as Brilique) to patients, work with Bristol-Myers Squibb toward leading the non-insulin diabetes market, set targets for annual "high single digit" revenue growth in China ...
    3-21-2013
  • Gene Expression Analysis Making Inroads
    both high protein and high fat, both of which stimulated greater maternal insulin production in the circulation but did not result in differences in maternal glucose circulation. ...
    3-15-2013
  • Shire Expands Into Neonatology with Premacure Acquisition
    The Phase II trial's primary goal is to restore the insulin-like growth factor 1 (IGF-1) ... occurring binding protein, insulin-like growth factor-1 binding protein-3 (IFGBP3). ...
    3-12-2013
  • Single Gene Mutation May Cause Type 1 Diabetes
    107. Expression of SIRT1-L107P in insulin-producing cells resulted in ... T1D is caused by autoimmune-mediated beta cell destruction leading to insulin deficiency. ...
    3-6-2013
  • Genome Editing for R&D and Therapeutics
    ... diseases. For example, in type 1 diabetes, one needs cells with a normally functioning insulin gene. Our technologies can create these cells efficiently." | Kathy Liszewski
    3-1-2013
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    Journal Articles

  • Quantitative Monitoring of Lipid Accumulation Over Time in Cultured...
    Shira Or-Tzadikario, Ran Sopher, Amit Gefen
    Tissue Engineering, Part C: Methods
    For each cell type, percentage of lipid area, number of droplets per cell, and droplet diameter were obtained every 2-3 days. In 3T3-L1 cultures, high insulin concentration ...
  • Does the Presence of Metabolic Syndome Influence Weight Loss...
    P. Evangelou, T. Tzotzas, G. Christou, M.S. Elisaf, D.N. Kiortsis
    Metabolic Syndrome and Related Disorders
    Very few data exist, however, about whether the presence of metabolic syndrome and insulin resistance (IR) influence the response of these subjects to weight-reducing ...
  • The Metabolic Syndrome in South Asians: Epidemiology, Determinants...
    Anoop Misra, Lokesh Khurana
    Metabolic Syndrome and Related Disorders
    Methods: The literature search has been carried out using the key words "insulin resistance, the metabolic syndrome, cardiovascular risk, diabetes, obesity, Asian Indians, and ...
  • β-Cell Function and Insulin Resistance in Pregnancy and Their...
    Sidhartha Das, Manas Kumar Behera, Sujata Misra, Anoj Kumar Baliarsihna
    Metabolic Syndrome and Related Disorders
    Function and Insulin Resistance in Pregnancy and Their Relation to Fetal Development Metabolic Syndrome and Related Disorders Background: Insulin resistance in pregnancy is ...

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