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  • Molecular Imaging Driving Development
    New imaging modalities including photoacoustic technology and clinical fluorescence will provide powerful approaches to translational medicine. High-Throughput Toxicity Screening ...
    8-1-2013
  • Removing the Receptor Deconvolution Bottleneck
    Similarly, in drug discovery, the success of phenotypic screening approaches ultimately ... However, a validated high-throughput approach-using a cell microarray technology developed ...
    8-1-2013
  • HTRF Applications in New Drug Discovery
    The result is a selective measurement of the assay specific signal, said Degorce. Cytokine Research Because of the compatibility of HTRF with high-throughput screening (HTS), "we ...
    7-1-2013
  • Microbioreactor Analysis Module
    TAP also provides custom automation solutions for biobanking, biological sample management, compound management and advanced high throughput screening applications. An analysis ...
    7-1-2013
  • Targeting Deranged Metabolism to Treat Cancer
    ... A selective R132H-IDH1 inhibitor (AGI-5198) identified through a high-throughput screening blocked, in a dose-dependent manner, the ability of the mutant enzyme (mIDH1) to produce ...
    7-1-2013
  • 10 Minute Charge Heterogeneity Analysis for Development and Quality...
    formulation development, analytical methods for formulation screening, and the development of a high-throughput charge heterogeneity method to accelerate formulation development. ...
    6-19-2013
  • Liquid Handling Needs a Helping Hand
    ... Unpredicted Domains A robotic arrayer (Kbiosystems) is used to print bacterial expression clones onto membranes over agar for ESPRIT high-throughput solubility screening. The ...
    6-15-2013
  • Advertorial: A Combinatorial, High-Throughput Approach to Protein...
    Technology drama-tically reduces strain development time and hence product development time via robotically enabled high-throughput, parallel-expression strain screening. ...
    6-15-2013
  • Macrocycles Shake Up Small Molecules
    conventional approach of performing high-throughput target-based assays on pre-defined ... he noted. "The generation and screening of our DNA-encoded collection of ...
    6-15-2013
  • Exquiron Gets New Diverse Screening Compound Library from Enamine
    Its services span from development of hit identification and profiling assays to compound selection, high-throughput screening, hit profiling and characterization, and SAR ...
    6-3-2013
  • Getting Creative with Mass Spec
    ... says enable this ability and could improve high-throughput multidimensional separations. ... Analysis and the POSI±IVE Exact Mass Screening Analysis to quickly analyze plant ...
    6-1-2013
  • Strategies to Optimize Cell Culture
    ... (high-throughput total sialic acid assay (HT-TSA)) that was developed at Biogen and based on his earlier work at MIT. One important application is faster screening of clones ...
    6-1-2013
  • Improving Compound Extraction Efficiency
    ... However, the automation methodology employed here (decapper and liquid handler) has proven suitable for a high-throughput screening of formulations using the in vitro skin ...
    6-1-2013
  • 24-Well 3D Cell Culture Kit
    TAP also provides custom automation solutions for biobanking, biological sample management, compound management and advanced high throughput screening applications. The RAFT ...
    6-1-2013
  • Microbial Picker
    provides tools that can be used in areas such as drug discovery, clinical research and pharmaceutical development, including high throughput screening, proteomics and genomics. ...
    6-1-2013
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    Journal Articles

  • A Time-Resolved Fluorescence Resonance Energy Transfer Assay...
    Yuhong Du, Robert W. Fu, Bin Lou, Jing Zhao, Min Qui, Fadlo R. Khuri, Haian Fu
    ASSAY and Drug Development Technologies
    A Time-Resolved Fluorescence Resonance Energy Transfer Assay for High-Throughput Screening of 14-3-3 Protein-Protein Interaction Inhibitors ASSAY and Drug Development Technologies ...
  • A Highly Specific Cell-Based High-Throughput Screening Assay...
    Hongxia Wang, Anisia J. Silva, Lynn Rasmussen, E. Lucile White, Jorge A. Benitez
    ASSAY and Drug Development Technologies
    A Highly Specific Cell-Based High-Throughput Screening Assay for Ligands of Cyclic Adenosine Monophosphate Receptor Protein in Gram-Negative Bacteria ASSAY and Drug Development ...
  • Enhanced Primer Selection and Synthetic Amplicon Templates Optimize...
    Carol M. Bruzzone, Patrick S. Tawadros, Lisa A. Boardman, Clifford J. Steer
    Genetic Testing and Molecular Biomarkers
    Genetic Testing and Molecular Biomarkers Aims: High Resolution Melting (HRM) screening and ... The evaluation of large populations of patients for multiple SNPs in a high throughput ...
  • Epitope Characterization of Sero-Specific Monoclonal Antibody...
    Cindi R. Corbett, Erin Ballegeer, Kelly A. Weedmark, M.D. Elias, Fetweh H. Al-Saleem, Denise M. Ancharski, Lance L. Simpson, Jody D. Berry
    Hybridoma
    of a panel of eight monoclonal antibodies (MAbs) generated to the non-toxic receptor-binding domain of BoNT/A (HC50/A) developed using a high-throughput screening approach. ...

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