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  • Toxicity Screens with Increased Insight
    be achieved by various new technologies that encompass multiplexing, low volumes, high-throughput screening, and advanced software for collection and analysis of large datasets. ...
    10-15-2013
  • Accelerating Precision Medicine with Efficient Drug Sensitivity...
    This webinar will review an implementation of the Echo ® liquid handler for high-throughput drug sensitivity screening at the Institute for Molecular Medicine in Finland. During ...
    10-2-2013
  • PMT-Based Hit Picking for HCA
    While this additional level of automation is comparable to that used in high-throughput screening (HTS), the need to capture and process images for the multivariate data ensures ...
    10-1-2013
  • Advertorial: OriGene Technologies
    The cDNA clone sets can be used for high-throughput functional screening to identify novel players in biological processes. 2. Protein Assay and Antibodies OriGene's 9,000 ...
    10-1-2013
  • Advertorial: Promega
    ... We offer custom services on products for genomics, proteomics, cellular analysis, and high-throughput screening. Scientists can start with an existing Promega product and change ...
    10-1-2013
  • Literature Review: Probing Protein Oligomerization
    Among these different approaches, fluorescence polarization, for instance, not only can measure association constants, but is also high-throughput amenable for potential screening ...
    9-25-2013
  • BASF Eyes Strategic Protein Growth, Buys Verenium for $62M
    microbial DNA directly from collected samples rather than the slower process of growing microbes in the lab, then identifies product candidates through high-throughput screening. ...
    9-20-2013
  • Cell-Based Assays: Getting Back to Basics
    ... Plasticell's high-throughput platform for differentiating stem cells, called combinatorial cell culture (CombiCult®), tackles this problem using a bead-based screening method that ...
    9-15-2013
  • Fine-Tuning Formulation Processes
    ... Despite high-throughput capabilities, KBI does not frequently perform highly systematic formulation screening or attempt to cover every parameter, buffer ingredient, or stabilizer. ...
    9-15-2013
  • Novel 3D Cell Culture Systems
    Following high-throughput, large-scale screening assays performed in 2D systems, these smaller, secondary screens in 3D microtissue models are more likely to be predictive of how ...
    9-15-2013
  • 3D High-Content Analysis of Spheroids
    Previously, two major roadblocks in the use of 3D spheroid cultures for drug testing were a lack of (1) a spheroid model in a reproducible and scalable high-throughput screening ...
    9-15-2013
  • Otsuka Acquires Astex for $866M
    analysis-a process the company says enables quicker discovery and development of compounds for target proteins implicated in diseases than possible with high-throughput screening. ...
    9-5-2013
  • How the ambr advanced microscale bioreactor can transform cell...
    Cell culture screening and process development programs have long been hampered by limited ... years with industry wide adoption of the ambr(tm) high throughput micro bioreactor system. ...
    9-1-2013
  • Purging Protein Profiling Problems
    ... on optimizing our protocol for high-throughput analysis," continues Dr. van der Burgt. ... While seemingly low-tech, this approach allows the screening of a large number of samples ...
    9-1-2013
  • Evotec and Jain Extend Research Collab in Skeletal Muscular Dystrophy
    using Evotec's assay development and screening capabilities while working toward the ... CROs with two aims: developing a high-throughput assay to identify drugs that could be ...
    8-21-2013
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    Journal Articles

  • High-Throughput Screening with Immobilized Metal Ion Affinity...
    Elma E.M.G. Loomans, Antoon M. van Doornmalen, Jesse W.Y. Wat, Guido J.R. Zaman
    ASSAY and Drug Development Technologies
    High-Throughput Screening with Immobilized Metal Ion Affinity-Based Fluorescence Polarization Detection, A Homogeneous Assay for Protein Kinases ASSAY and Drug Development ...
  • High-Throughput Screening Using β-Lactamase Reporter-Gene Technology...
    Julia Oosterom, Els J.P. van Doornmalen, Sendy Lobregt, Marion Blomenröhr, Guido J.R. Zaman
    ASSAY and Drug Development Technologies
    High-Throughput Screening Using β-Lactamase Reporter-Gene Technology for Identification of Low-Molecular-Weight Antagonists of the Human Gonadotropin Releasing Hormone Receptor ...
  • A High-Throughput Screening Strategy to Overcome Virus Instability
    Lynn Rasmussen, Clinton Maddox, Blake P. Moore, William Severson, E. Lucile White
    ASSAY and Drug Development Technologies
    A High-Throughput Screening Strategy to Overcome Virus Instability ASSAY and Drug Development Technologies Abstract Respiratory syncytial virus (RSV) is a widely distributed ...
  • High Throughput Screening via Mass Spectrometry: A Case Study...
    Can C. Özbal, William A. LaMarr, John R. Linton, Donald F. Green, Arrin Katz, Thomas B. Morrison, Colin J.H. Brenan
    ASSAY and Drug Development Technologies
    High Throughput Screening via Mass Spectrometry: A Case Study Using Acetylcholinesterase ASSAY and Drug Development Technologies Mass spectrometry-based screening can be applied to ...

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