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Search Results - Hearing Loss
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  • GenVec Board Votes to Dissolve Company
    GenVec ended 2012 with a 47% revenue loss down to $9.4 million, a slide the company blamed on year-over-year declines of $5.6 million in its hearing loss and balance disorders ...
    5-29-2013
  • Who Owns Your Genes?
    (UMDNJ) say their study raises an alarm about the loss of individual "genomic liberty." ... The U.S. Supreme Court will review genomic patent rights in an upcoming hearing on April ...
    3-27-2013
  • Human Gene Connectome Mapped
    ... They then applied other gene connectomes to detect Ehlers-Danlos syndrome and sensorineural hearing loss disease-causing genes. The team also developed a functional genomic ...
    3-20-2013
  • New Life for Embryonic Stem Cells
    ... Potential Treatment for Hearing Loss But other new findings may impact regenerative medicine and the future of hES cells as new applications for these cells emerge. Last year ...
    1-30-2013
  • Hearing Better Through Chemistry
    Drug or stem cell therapies for hearing loss may replace mechanical devices within a few years. For that person in your life with a hearing loss who refuses to countenance a ...
    12-19-2012
  • GenVec Slashes Workforce by 30%
    being reduced in virtually all areas, but we have focused on limiting the impact of our collaboration with Novartis to develop treatments for hearing loss and balance disorders." ...
    9-25-2012
  • Cell Therapy Improves Hearing in Deaf Rodents
    proportion of patients with hearing impairment, and is defined primarily by damage to the SGNs, rather than the hair cells. Unfortunately, while loss of hair cells can be ...
    9-13-2012
  • GenomeQuest Awards $120K in Grants to Support NGS-Based Diagnostics
    ... disorders, familial cancer syndromes, cardiology, congenital hearing loss, neurogenetics/neuromuscular disorders, genetic and metabolic pediatric disorders, and intersex disorders. ...
    1-11-2012
  • FDA Aims to Bridge Communication Gap with Drug Industry During...
    Drug User Fee Act (PDUFA V) when FDA holds a day-long public hearing on the topic. ... As big biopharma struggles with the loss of patents for blockbusters, and with meager ...
    10-20-2011
  • FDA Thumps Industry, Patients Feel the Pain
    Therapeutics, the maker of a weight-loss drug once seen as a potential blockbuster, ... During a February hearing, the FDA made it plain to drug companies that it considers the ...
    9-15-2011
  • BioFocus Collaborates with Michael J. Fox Foundation on Parkinson...
    the Usher III Initiative, a nonprofit organization focused on developing treatments for Usher syndrome type III, a rare genetic disorder that causes the loss of hearing and vision. ...
    7-13-2011
  • Sanofi and Audion Ink Hearing Loss Research Deal
    Sanofi entered into a two-year research collaboration with Audion Therapeutics to develop treatments for hearing loss. The companies say that they will optimize small molecules by ...
    6-16-2011
  • Making Follow-On Biologics a Reality
    In November 2010, FDA held a public hearing to solicit input on 1) scientific and ... to replace the original product in the marketplace prior to loss of market share to FOBs. ...
    6-1-2011
  • FDA and EMA Take Steps to Restrict Avastin Use in Breast Cancer
    Avastin's label voluntarily, so the FDA has issued a Notice of Opportunity for a Hearing. ... pressure, headaches, confusion, seizures, and vision loss from swelling of the brain. Dr. ...
    12-17-2010
  • Otonomy Secures $38.5M to Support Pipeline of Therapies for Ear...
    Future studies are reportedly being planned for acute onset hearing loss. Otonomy is also developing OTO-203, an antibiotic/steroid combination product, for the treatment of otitis ...
    8-30-2010
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    Journal Articles

  • Sensory Epithelial Cells Acquire Features of Prosensory Cells...
    Lei Zhang, Zhengqing Hu
    Stem Cells and Development
    may provide a novel approach to generate epithelial progenitors for use in cell replacement therapy to treat a number of human diseases, such as hearing loss and vision loss.
  • Is S-nitrosylation of Cochlear Proteins a Critical Factor in...
    Samson Jamesdaniel, Senthilvelan Manohar, Sneha Hinduja
    Antioxidants & Redox Signaling
    In addition, co-treatment with Trolox, an inhibitor of peroxynitrite, attenuated cisplatin-induced S-nitrosylation of cochlear proteins and prevented the associated hearing loss. ...
  • Next-Generation Sequencing in Genetic Hearing Loss
    Denise Yan, Mustafa Tekin, Susan H. Blanton, Xue Zhong Liu
    Genetic Testing and Molecular Biomarkers
    Next-Generation Sequencing in Genetic Hearing Loss Genetic Testing and Molecular Biomarkers The advent of the $1000 genome has the potential to revolutionize the identification of ...
  • Audiologic and Genetic Features of the A3243G mtDNA Mutation
    Richard J. Vivero, Xiaomei Ouyang, Yeunjung Grant Kim, Wendy Liu, Lilin Du, Denise Yan, Xue Zhong Liu
    Genetic Testing and Molecular Biomarkers
    Methods: A single family with maternally inherited diabetes and hearing loss was recruited. Genomic DNA was subject to Polymerase Chain Reaction-Restriction Fragment Length ...

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