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  • Analysis of N-Glycan Released from Biopharmaceutical Glycoproteins...
    They have to be derivatized with a chromaphore (2-aminobenzamide, 2-AB) in order to be analyzed by HPLC and UV detection. High performance anion exchange chromatography with pulsed ...
    7-30-2013
  • Downstream Process Bottlenecks
    ... Novasep's Hipersep hydraulic system along with an HPLC column for small biomolecule purification at the company's facility in Pompey, France. Fabien Rousset, deputy director and ...
    7-1-2013
  • Reducing the Cost of Peptide Synthesis
    ... to resolve on conventional reverse-phase HPLC can be detected with UPLC, contributing to ... Endotoxins are removed during HPLC purification, explains John McKinley of American ...
    7-1-2013
  • More Than a Messenger: A New Class of Drugs-mRNA-Based Therapeutics
    ... additional removal of double-stranded RNA by high-performance liquid chromatography (HPLC) may avoid the residual induction of type I interferons (IFNs) and proinflammatory ...
    6-14-2013
  • Getting Creative with Mass Spec
    provides a different selectivity in HPLC compared to the classical reversed phase ... efficiency and increased sensitivity in HPLC is the development of the Fused-Core(tm) ...
    6-1-2013
  • Strategies to Optimize Cell Culture
    ... Currently HPLC is most often used to measure SA content, but the process can take five ... NGNA) because they have the same fluorescence spectra. HPLC can distinguish the two." ...
    6-1-2013
  • Pushing the Boundaries in Chromatography
    of separation to HPLC/UHPLC for full characterization of samples, the company reports. ... By contrast, conventional high-performance liquid chromatography (HPLC) solvents are toxic ...
    6-1-2013
  • Syringe Filters
    particulate-laden samples through a filter and eliminate the need for sequential filtration. All Captiva Premium syringe filters are supplied with a HPLC or LC/MS Certificate.
    5-15-2013
  • Sample Prep/LC System
    LC-MS/MS performance can be further enhanced low-volume gradient operation at flow rates of 1-2,000 mL/min. Because it features two channels of liquid HPLC separation, mass ...
    5-15-2013
  • Reversed-Phase HPLC Column
    The PRP-C18 reversed-phase HPLC column expands the pH range of reversed-phase chromatography, providing separations over an extended column life. Stability to pH extremes extends ...
    5-15-2013
  • Boosting Downstream Productivity
    ... Large-Scale HPLC To complete its range of single-use Tangential Flow Filtration (TFF) ... bag. "Many blockbusters already include HPLC in their purification process: recombinant ...
    4-15-2013
  • UHPLC Core-Shell Media
    of advanced technology solutions for separation science techniques in the areas of sample preparation, high-performance liquid chromatography (HPLC) and gas chromatography (GC). ...
    4-15-2013
  • Peptide Mapping Biocolumns
    for the analysis of the peptides produced by enzymatic digest of proteins. The 2.7 µm particle size enables UHPLC performance on HPLC systems, which can deliver high resolution.
    4-15-2013
  • Scaling Up Peptide Drugs
    ... The cost of production "has to be driven down to make it economical." Reverse-phase HPLC ... due to progress in analytical technology and improvements in preparative HPLC media." ...
    4-1-2013
  • Peptide Chromatography Columns
    Acquity UPLC® CSH130 C18 and XSelect(tm) HPLC CSH130 C18 columns allow for the analysis and purification of peptides and for the quality of information generated by UPLC, LC, and ...
    3-15-2013
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    Journal Articles

  • Method for the Detection of Nucleosides, Bases, and Hydroxylated...
    DOUGLAS R. McCABE, KENNETH HENSLEY, IAN N. ACWORTH
    Journal of Medicinal Food
    Method for the Detection of Nucleosides, Bases, and Hydroxylated Adducts Using Gradient HPLC with Coulometric Array and Ultraviolet Detection Journal of Medicinal Food
  • Ethanol Extract of Lycopus lucidus Elicits Positive Inotropic...
    Hao Zhen Cui, Hyun Cheol Oh, Xiang Li, Yun Jung Lee, Kyung Woo Cho, Dae Gill Kang, Ho Sub Lee
    Journal of Medicinal Food
    Three active components, rosmarinic acid, betulininc acid, and oleanolic acid were identified in ELT by HPLC analysis. ELT increased atrial dynamics in a concentration-dependent ...
  • Comparative Protective Effect of Hawthorn Berry Hydroalcoholic...
    Hassan Malekinejad, Vahid Shafie-Irannejad, Rahim Hobbenaghi, Seyed Hamed Tabatabaie, Seyed-Mehdi Moshtaghion
    Journal of Medicinal Food
    Colitis was induced by administration of 1 ml acetic acid (4%) via polyethylene catheter intra-rectally. HPLC analyses showed that HBE contained 0.13 and 0.5 % oleanolic acid (OA) ...
  • Crude Dietary Polysaccharide Fraction Isolated from Jackfruit...
    Yin-Feng Tan, Hai-Long Li, Wei-Yong Lai, Jun-Qing Zhang
    Journal of Medicinal Food
    The composition of polysaccharides was examined by the Sephadex-G200 column chromatography and high performance liquid chromatography (HPLC) methods. Thymus index (TI) and ...

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