Current Issue

View Larger Image

Past Issues Free Subscriptions
Sponsored
Keywords



Search Results - Glycan Analysis
 More »

  • Analysis of N-Glycan Released from Biopharmaceutical Glycoproteins...
    Protein glycosylation affects the safety, efficacy, and serum half-life of these biopharmaceuticals. Therefore analysis of the glycan pattern is an important issue for ...
    7-30-2013
  • Mass Spec Provides Peek into PTMs
    ... metabolites in tissues, but it has not been previously applied to N-linked glycan analysis. "Using this basic approach, global snapshots of major cellular N-linked ...
    5-15-2013
  • The ABCs of Glycoproteins: How to Combine Analytics, Biology...
    The number and similarity of possible structures of glycans place tremendous demands on the analytical techniques. Advances in analytical technology for glycan analysis, from ...
    3-15-2013
  • Optimizing the Quality and Accuracy of Biopharmaceutical Analysis...
    ProZyme and Agilent are collaborating to develop automated, high-precision workflows for glycan analysis. In this Webinar You Will Learn How the importance of monoclonal antibody ...
    2-19-2013
  • Fast Forward, Ezose Partner on MS Biomarker Discovery
    Ezose was established in 2009 in the U.S. as a subsidiary of Japanese firm Shionogi's diagnostics division. The firm's Glycan Map is a glycan analysis technology platform that ...
    10-24-2012
  • Optimizing Protein Expression
    insect cells to synthesize human-type glycan structures. "It turns out that insect ... the typical space shuttle 10-day mission was often too small for diffraction analysis. ...
    9-15-2012
  • Enabling High-Throughput Glycomics
    Quantitative Glycan Analysis for Biomarker Discovery and Characterization of Biotherapeutics Glycomics is defined as the study of both free sugars and of the complex sugar chains ...
    7-1-2012
  • Finding the Right Balance in HPLC
    ... well as distribution among various glycan forms," Dr. Cohen explains. He sees the underappreciated in-between stage of glycopeptide analysis-that can show to which peptide the ...
    6-1-2012
  • Maximizing Mass Spec's Potential
    ... want to have information about where the glycan is attached to the protein in order to ... as N- and O-glycans that can complicate analysis by MS. Therefore, "it is normally ...
    5-15-2012
  • Accelerating Glycan Characterization
    ... This assists in resolving glycan structures when data for the glycans is not yet available in the software database or for de novo glycan analysis. Conclusion Because glycans ...
    5-15-2012
  • Biomarker Discovery Methods Evolving
    ... components: (1) bead-based chemoselective glycan enrichment known as Glycoblotting, (2) ... plate format, and (3) MALDI-TOF mass spectrometry coupled to bioinformatic analysis. ...
    5-1-2012
  • Ezose, Hirosaki University Sign Glycomics Partnership to Identify...
    with its SwetBlot® automated glycan sample-processing technology, MALDI-MS quantitative detection, and analysis software to generate qualitative and quantitative results. ...
    4-23-2012
  • Cracking the PTM Code
    ... which has allowed for detection of more glycan species than before. "The mAb-Glyco LC-MS chip from Agilent is amenable to the analysis of N-linked glycosylated therapeutic ...
    4-15-2012
  • Waters, Ireland's NIBRT Join Forces to Improve Product Analytics
    The facility will also educate scientists on existing and upcoming U.S. and European drug regulations. "The combination of Pauline Rudd's expertise in glycan analysis and Waters ...
    3-27-2012
  • High-Throughput Protein-Expression Challenges
    ... insect cells with genes encoding the N-glycan processing functions needed to 'humanize' ... and the media is used for the analysis of binding specificities of mAbs," says Dr. ...
    1-1-2012
  • More »

    Journal Articles

  • Review and Hypothesis: Does Graves' Disease Develop in Non-Human...
    Sandra M. McLachlan, Kristine Alpi, Basil Rapoport
    Thyroid
    All other placental mammals lack one N-glycan in the shed TSHR A-subunit, the primary ... Neither serum nor thyroid tissue from this gorilla were available for analysis. The survey ...
  • Lectin Microarrays for Glycomic Analysis
    Garima Gupta, Avadhesha Surolia, Srinivasa-Gopalan Sampathkumar
    OMICS: A Journal of Integrative Biology
    based on chromatography, mass spectrometry, glycan microarrays, and glyco-informatics. ... versatile platform for rapid high throughput analysis of glycoforms of biological samples. ...
  • Glycan Characterization of PSA 2-DE Subforms from Serum and Seminal...
    Ariadna Sarrats, Radka Saldova, Josep Comet, Niaobh O'Donoghue, Rafael de Llorens, Pauline M. Rudd, Rosa Peracaula
    OMICS: A Journal of Integrative Biology
    analysis of F3, the more abundant PSA subform, showed a higher proportion of alpha 2-3 sialic acid and a decrease in core fucosylated glycans in the PCa sample. These N-glycan ...
  • The i Blood Group Antigen as a Marker for Umbilical Cord Blood...
    Tia Hirvonen, Heli Suila, Annika Kotovuori, Ilja Ritamo, Annamari Heiskanen, Pertti Sistonen, Heidi Anderson, Tero Satomaa, Juhani Saarinen, Sari Tiitinen, Jarkko Räbinä, Saara Laitinen, Suvi Natunen, Leena Valmu
    Stem Cells and Development
    We used flow cytometry and mass spectrometric glycan analysis and discovered that linear poly-N-acetyllactosamine structures are expressed in UCB-derived MSCs, but not in cells ...

GEN Webinars

View »

GEN Web Briefs

View »

GEN Poll

More » Poll Results » Archive »

Top Paid Women in Biopharma

Do you think the women on our list of the 20 top paid women executives in biopharma are underpaid?

Suggest a Poll