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  • Multitasking Multiplex Assays
    ... NGS is providing tremendous opportunities for genomic-based diagnostic tests and for drug developers to better guide patient care. Gene-disease associations have the potential to ...
    10-15-2013
  • Deciphering RNA Secondary Structure
    RNAs play an integral part in all kingdoms of life and mediate critical processes from gene regulation to genomic maintenance and protein synthesis. RNAs also have an amazing ...
    10-15-2013
  • Identifying & Isolating High-Producer Clones
    the screening of hundreds to thousands of clones with significantly reduced labor investment, identifying high producers without the need for additional gene-amplification steps. ...
    10-15-2013
  • Growing and Preparing Adult Stem Cells
    ... Typically they're genetically manipulated in some way to give them their desired properties, whether that means replacing a defective gene, conveying pathogen resistance, or making ...
    10-15-2013
  • iRNA's Antiviral Path in Mammals Not Abandoned, Just Less Traveled
    RNAi, or interference RNA, was already known to exist in mammals, but most researchers believed that its functions were limited to gene regulation, and did not extend to antiviral ...
    10-11-2013
  • Diverse Neurological Disorders Appear to Share Tangled Metabolic...
    This study encompasses gene expression defects specific to Lesch-Nyhan, a relatively rare disorder, as well as a range of related metabolic defects, which appear to work together ...
    10-10-2013
  • Vivaldi Buys Flu Vaccine R&D Assets from Baxter
    property, clinical data, knowhow, and materials-for live attenuated influenza vaccines (LAIVs) in which the gene for influenza nonstructural protein 1 (NS1) has been fully deleted. ...
    10-10-2013
  • Long Noncoding RNAs: Why You Need to Know about Them Now
    are believed to exist) and the multitude of roles they are believed to play including structural roles, modulation/fine-tuning of gene expression in vivo, and epigenetic effects. ...
    10-10-2013
  • U.S. Research Will "Pay Dearly" for Shutdown, ASCB Warns
    Dr. Cleveland said his laboratory last month identified a method for silencing a gene in neurodegenerative disease, and lined up a research partner to launch a clinical trial. "We ...
    10-9-2013
  • Cell Therapy: Pushing Cells Around
    ... Cells that are cultured in low oxygen conditions dramatically change their gene expression and protein secretion. Cells cultured in three-dimensional (3D) environments differ ...
    10-8-2013
  • A Marriage Gene for Better or Worse
    based at the University of California, Berkeley, it matters whether that person possesses short or long variants of the serotonin transporter gene, the so-called happy hormone. ...
    10-8-2013
  • Ovarian Cancer Treatment Options Multiply
    ... New diagnostics are vital. "In the future, whole-gene sequencing, RNA sequencing, and proteomic analysis also will be helpful in characterizing tumors, and measuring circulating ...
    10-8-2013
  • Cells' Trash-Clearing Function May Be an Alzheimer's Drug Target
    To investigate the role of autophagy in amyloid beta metabolism, Per Nilsson, Ph.D., and colleagues deleted an important gene for autophagy (Atg7) in a mouse model of Alzheimer's ...
    10-4-2013
  • Developments in Cancer Vaccines and Gene Therapy
    Philadelphia PA UNITED STATES http://bit.ly/14CccfE
    10-3-2013
  • Epigenetic Markers Found for Head and Neck Cancers
    That test, called the quantitative Malignancy Index Diagnostic System, quantifies the expression levels of 14 genes associated with the FOXM1 cancer gene, and converts the ...
    10-2-2013
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    Journal Articles

  • Gene Transfer to Subdermal Tissues via a New Gene Gun Design
    John Dileo, Theodore E. Miller, Sophie Chesnoy, Leaf Huang
    Human Gene Therapy and Part B: Methods
    Gene Transfer to Subdermal Tissues via a New Gene Gun Design Human Gene Therapy and Part B: Methods Although particle-mediated gene transfer technology (gene gun) has been applied ...
  • Combined Gene Therapy with Hypoxia-Inducible Factor-1α and Heme...
    Suk Ho Bhang, Ju Hee Kim, Hee Seok Yang, Wan-Geun La, Tae-Jin Lee, Ga Hee Kim, Hyun Ah Kim, Minhyung Lee, Byung-Soo Kim
    Tissue Engineering, Part A
    Combined Gene Therapy with Hypoxia-Inducible Factor-1α and Heme Oxygenase-1 for Therapeutic Angiogenesis Tissue Engineering, Part A Transfection with either hypoxia-inducible ...
  • Dystrophin Gene Repair in mdx Muscle Precursor Cells In Vitro...
    Carmen Bertoni, Thomas A. Rando
    Human Gene Therapy and Part B: Methods
    Dystrophin Gene Repair in mdx Muscle Precursor Cells In Vitro and In Vivo Mediated by RNA-DNA Chimeric Oligonucleotides Human Gene Therapy and Part B: Methods Point mutations in ...
  • Gene Transfer of a Chimeric Trans-Activator Is Immunogenic and...
    Martine Latta-Mahieu, Magali Rolland, Catherine Caillet, Manping Wang, Philippe Kennel, Irene Mahfouz, Isabelle Loquet, Jean-François Dedieu, Abderrahim Mahfoudi, Emanuelle Trannoy, Vincent Thuillier
    Human Gene Therapy and Part B: Methods
    Gene Transfer of a Chimeric Trans-Activator Is Immunogenic and Results in Short-Lived Transgene Expression Human Gene Therapy and Part B: Methods Pharmacologic gene regulation is a ...

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