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Search Results - Gene Expression
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  • Mass Spec Provides Peek into PTMs
    ... N-glycanaseF to release N-glycans: Expression profiles of two representative released ... proteins products generated from a single gene, including those derived from alternative ...
    5-15-2013
  • Highlights from AACR
    EMD Millipore reports that its SmartFlare RNA detection probes detect native mRNA or miRNA in live cells in a nontoxic manner without affecting gene expression or production of a ...
    5-15-2013
  • A First: hESCs Generated from Somatic Cells
    Additionally, "we show the battery of tests that show these cells are now off the initial somatic cell gene expression and now they look like embryonic stem cells," he said. While ...
    5-14-2013
  • 6 Considerations for Multiplex qPCR Setup
    Amplification of the multiple targets in a single sample can be influenced by factors including gene expression levels, primer interactions, and competition for reaction reagents. ...
    5-13-2013
  • Induced Pluripotent Stem Cells: A U.S. Patent Landscape Analysis
    factor into the chromosome or extra-chromosomally (e.g., episomal expression). ... factors OCT, Myc, or Klf ("any gene" in Figure 1 ) and there is a downward ...
    5-13-2013
  • Companion Diagnostics: 52 Pick-Up
    ... Skyline Diagnostics and Clavis Pharma Agreement announced September 6, 2011 Research agreement, under which Skyline agreed to investigate gene expression biomarkers for selection ...
    5-9-2013
  • Cancer Diagnostics, Pushing the Boundaries
    Molecular techniques and technologies to probe alterations in gene and protein expression that may contribute to the development, progression, prognosis, heterogeneity, therapeutic ...
    5-8-2013
  • The Tumor Microenvironment as a Drug Target, Part II
    ... Lead author Julia Tchou, M.D., Ph.D. of Penn and Wistar colleagues asked whether the reported gene expression profile differences between CAFs in breast cancer stroma and normal ...
    5-7-2013
  • Protein Complex Mutated in about 20% of All Cancers
    or to allow the expression of genes necessary for the growth or function of the cell. ... Kadoch, "a type of mutation called a chromosomal translocation in the gene encoding one of ...
    5-6-2013
  • Analytik Jena Acquires Sepsis Test Among SIRS-Lab Assets
    ... In addition to the sepsis test, SIRS-Lab was also developing a gene expression product (SIQNATURE®) to indicate the body's immune response to an infection. A related test ...
    5-6-2013
  • Turning Off Cancer's "Master Regulator"
    triple negative cells-those that lack hormone receptors or HER2 gene amplification. ... Dr. Resar's team blocked HMGA1 expression in aggressive breast cancer cells and followed ...
    5-3-2013
  • Exposing the Exposome
    In addition to the DNA damage model for carcinogenesis, recent years revealed that gene expression and function may also be modulated by mechanisms that do not involve mutagenesis, ...
    5-1-2013
  • Biomarkers Take Center Stage
    ... Studies published in the past year have looked at somatic mutations, gene copy number aberrations, gene expression abnormalities, protein and miRNA expression, and DNA methylation, ...
    5-1-2013
  • Gene Expression Analysis in Living Cells
    RNA Detection Reagent Enables Major Research Step Forward Detecting gene expression has traditionally been limited to technologies that examine expression in lysed or fixed cell ...
    5-1-2013
  • Twin Effort Hones In on Membrane Proteins
    ... Clients send Synthelis the gene sequence or any genetic material from a membrane protein of interest. Synthelis carries out a feasibility study to test the expression conditions ...
    5-1-2013
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    Journal Articles

  • Hepatic Differentiation of Human Embryonic Stem Cells Is Promoted...
    Toshio Miki, Alexander Ring, Jörg Gerlach
    Tissue Engineering, Part C: Methods
    Metabolism, hepatocyte-specific gene expression, protein expression, and hepatic function were evaluated after 20 days. Significantly upregulated hepatic gene expression was ...
  • Identification of the Chondrocyte Lineage Using Microfibril-Associated...
    Stephen Rapko, Mindy Zhang, Brenda Richards, Elizabeth Hutto, Sandra Dethlefsen, Stephen Duguay
    Tissue Engineering, Part C: Methods
    Performance characteristics of gene expression assays formed by the analysis of cartilage link protein with normalization to either standard reference genes or to MAGP2 were ...
  • Molecular Mechanisms of Biofilm Infection: Biofilm Virulence...
    Priscilla L. Phillips, Gregory S. Schultz
    Advances in Wound Care
    In many cases they were inactivated planktonic virulence factor genes. These results further demonstrate the opposing patterns of gene expression between acute planktonic bacterial ...
  • Hepatic Maturation of Human Fetal Hepatocytes in Four-Compartment...
    Alexander Ring, Jörg Gerlach, Grant Peters, Benjamin J. Pazin, Crescenzio F. Minervini, Morris E. Turner, Robert L. Thompson, Fabio Triolo, Bruno Gridelli, Toshio Miki
    Tissue Engineering, Part C: Methods
    Metabolism activity, hepatocyte-specific gene expression, protein expression, and hepatic function were investigated. Increased glucose consumption and lactate production indicated ...

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