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  • Deciphering RNA Secondary Structure
    critical processes from gene regulation to genomic maintenance and protein synthesis. ... are useful for the diagnosis of and therapy for cancer and viral disease." tRNA ...
    10-15-2013
  • Growing and Preparing Adult Stem Cells
    ... Lentiviral Reprogramming Cells used for therapy generally aren't just taken from a donor, ... whether that means replacing a defective gene, conveying pathogen resistance, or making ...
    10-15-2013
  • Diverse Neurological Disorders Appear to Share Tangled Metabolic...
    This study encompasses gene expression defects specific to Lesch-Nyhan, a relatively rare ... pathways are identified, they may become good targets for more effective forms of therapy. ...
    10-10-2013
  • Cell Therapy: Pushing Cells Around
    This is potentially a significant advance in the field of cell therapy-no need for the ... Cells that are cultured in low oxygen conditions dramatically change their gene expression ...
    10-8-2013
  • Ovarian Cancer Treatment Options Multiply
    ... genetic analysis can help identify patients who benefit from PARP inhibitor therapy. ... New diagnostics are vital. "In the future, whole-gene sequencing, RNA sequencing, and ...
    10-8-2013
  • Developments in Cancer Vaccines and Gene Therapy
    Philadelphia PA UNITED STATES http://bit.ly/14CccfE
    10-3-2013
  • Young Companies in the Money: 25 Firms to Watch
    ... 4,5 Date announced: July 9 Purpose: Commercialization of Glybera, the first gene therapy to receive regulatory approval in Europe, as well as the co-development of a gene ...
    10-2-2013
  • Sun Pharma, Intrexon Team Up to Target Ocular Diseases
    is to engineer a gene-based ocular treatment in which the concentration, location, and timing of protein expression can be controlled with small molecule therapy," said Samuel ...
    10-1-2013
  • DNA Vaccines Free from Mobile DNA
    ... In 2004, Merck scientists reported that whole plasmids could integrate into mouse genomes after intramuscular injection for gene therapy. The insertions sites were not targeted and ...
    10-1-2013
  • HIV Researchers Seek a Potential Cure
    ... Both patients had been treated with antiretroviral therapy long-term before developing lymphoma. "These findings might well alter the current thinking about HIV and gene therapy," ...
    10-1-2013
  • Advertorial: United States Pharmacopeial Convention
    ... of protein A; cellular and tissue-based products; gene therapy products; growth factors and cytokines; ancillary materials in cell manufacturing; and immunogenicity testing. ...
    10-1-2013
  • Cutting Melanoma Off at the Pass
    They found that resistant melanomas acquired a mutation in the MEK2 gene and multiple ... Their findings also uncovered a new potential target for melanoma therapy, a protein ...
    9-20-2013
  • Studying Tumor Mutations via a Network Approach
    stratification (NBS), a method to integrate somatic tumor genomes with gene networks. ... outcomes such as patient survival, response to therapy, or tumor histology," continued Dr. ...
    9-16-2013
  • Personalized Medicine and Patent Eligibility
    to respond to a particular therapy. More accurate diagnoses based on analyses of gene sequences and other biomarkers should permit targeted treatments to achieve improved outcomes. ...
    9-16-2013
  • Designing and Managing Modern Biobanks
    ... samples from patients with metastatic cancers that have failed several lines of therapy. ... utility in downstream applications, such as expression analysis by gene chip technology." ...
    9-15-2013
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    Journal Articles

  • Gene Therapy for Thyroid Cancer: Current Status and Future Prospects
    Christine Spitzweg, John C. Morris
    Thyroid
    Gene Therapy for Thyroid Cancer: Current Status and Future Prospects Thyroid Despite multimodality treatment for thyroid cancer, including surgical resection, radioiodine therapy, ...
  • Combined Gene Therapy with Hypoxia-Inducible Factor-1α and Heme...
    Suk Ho Bhang, Ju Hee Kim, Hee Seok Yang, Wan-Geun La, Tae-Jin Lee, Ga Hee Kim, Hyun Ah Kim, Minhyung Lee, Byung-Soo Kim
    Tissue Engineering, Part A
    Combined Gene Therapy with Hypoxia-Inducible Factor-1α and Heme Oxygenase-1 for Therapeutic Angiogenesis Tissue Engineering, Part A Transfection with either hypoxia-inducible ...
  • Gene Therapy of Murine Solid Tumors with T Cells Transduced with...
    Ni Jin, Wei Chen, Bruce R. Blazar, S. Ramakrishnan, Daniel A. Vallera
    Human Gene Therapy and Part B: Methods
    Gene Therapy of Murine Solid Tumors with T Cells Transduced with a Retroviral Vascular Endothelial Growth Factor-Immunotoxin Target Gene Human Gene Therapy and Part B: Methods ...
  • Gene Therapy for Cystic Fibrosis Using E1-Deleted Adenovirus...
    Richard C. Boucher, Michael R. Knowles, Larry G. Johnson, John C. Olsen, Raymond Pickles, James M. Wilson, John Engelhardt, Yiping Yang, Mariann Grossman
    Human Gene Therapy and Part B: Methods
    Gene Therapy for Cystic Fibrosis Using E1-Deleted Adenovirus: A Phase I Trial in the Nasal Cavity. University of North Carolina at Chapel Hill, Chapel Hill, North Carolina Human ...

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