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  • Childhood Epilepsy Tied to Mutations in Unexpected Genes
    which is also involved with Angelman's syndrome, also offers the possibility that children with mutations only in this gene might benefit from the existing therapy for Angelman's. ...
    8-9-2013
  • SCT Licenses Worldwide Rights to Prostate Cancer Stem Cell Assets
    The group has compiled gene expression profiles for various cell types present in prostate ... helps explain how prostate cancer stem cells form a base for post-therapy recurrence. ...
    8-9-2013
  • What Junk DNA? It's an Operating System
    Noncoding gene sequences control gene expression and influence disease processes. In the August 1 issue of CELL , researchers from the Gene and Stem Cell Therapy Program at ...
    8-6-2013
  • Don't Call It "Junk DNA" Anymore
    Based in the institute's gene and stem cell therapy program, the researchers say they have unraveled a previously unknown mechanism for regulating the activity of genes, thus ...
    8-5-2013
  • Life Tech, RainTree Launch Oncology Testing, Patient Data Initiatives
    ... tools giant going beyond companion diagnostics, into development of a gene therapy that uses infusions of the patients' own T cells genetically engineered to attack their tumors. ...
    8-5-2013
  • Hematologic Diagnostics Go with the Flow
    ... disease in pediatric patients with acute lymphoblastic leukemia after induction therapy. ... A locus-specific DNA probe for 5q31 (EGR1 gene) was used, along with a control probe ...
    8-1-2013
  • Life Tech Licenses Dynabeads to Novartis, with Cancer Therapy...
    tools giant going beyond companion diagnostics-into development of a gene therapy that uses infusions of the patients' own T cells genetically engineered to attack their tumors. ...
    8-1-2013
  • Big Need in IBD: Drugs to Slow Progression
    for those that justify initiation of therapy earlier in the course of IBD, as well as ... A recent finding at the University of Cambridge resulted in a gene expression profile to ...
    8-1-2013
  • High School Whiz Kids Win Scientific Prestige . . . and Big Bucks
    ... Linking a Gene Mutation to Parkinson's Michael Yan identified the underlying biomechanism ... "photothermal therapy (PPT)," whereby patients are injected with gold nanoparticles. ...
    8-1-2013
  • ReGenX, Audentes Team Up to Develop Rare Muscle Disease Treatments
    using AAV gene therapy technology and we feel rAAV8 and rAAV9 are the most promising vectors to achieve this goal," said Matthew R. Patterson, president and CEO of Audentes. ...
    7-30-2013
  • FDA OKs Cepheid Combination TB, Drug Resistance MDx
    gene. The firm added that the Xpert MTB/RIF Assay was designed for use on its GeneXpert® Systems. "Patients with multidrug-resistant TB need more intensive and prolonged therapy...
    7-26-2013
  • CRISPR/Cas Comes of Age-Almost
    ... tool for altering gene sequence or gene expression. It will be interesting to begin to explore the use of these reagents for therapy, carefully taking into account the ...
    7-24-2013
  • NIH Ushering Genome Sequencing Toward the Clinic with Grants...
    along with their parents, in an effort to identify causative gene alterations. Dr. ... in a statement. "Genome sequencing has vast potential to uncover new targets for therapy. ...
    7-23-2013
  • RT-PCR: Ready for Prime Time?
    parameters and justification for reference gene selection, hindering critical evaluation ... decisions for the remainder of the therapy or subsequent rounds of therapy." Dr. ...
    7-23-2013
  • AskBio, Genzyme Ink Gene Therapy Cross-Licensing Agreement
    (AskBio) this week said it had entered into a non-exclusive licensing agreement, through which the firm is granting Genzyme rights to its Duplex gene therapy vector technology. ...
    7-17-2013
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    Journal Articles

  • Safety and Efficacy of a Genetic Vaccine targeting Telomerase...
    Alessandra Gavazza, George Lubas, Arthur Fridman, Daniela Peruzzi, Joseph A Impellizeri, Laura Luberto, Emanuele Marra, Giuseppe Roscilli, Gennaro Ciliberto, Luigi Aurisicchio
    Human Gene Therapy and Part B: Methods
    Safety and Efficacy of a Genetic Vaccine targeting Telomerase plus Chemotherapy for the therapy of canine B-cell lymphoma Human Gene Therapy and Part B: Methods Client-owned pet ...
  • BMP-2 plasmid DNA as a substitute for BMP-2 protein in bone tissue...
    Fiona Wegman, Yvonne van der Helm, F Cumhur Oner, Wouter Dhert, Jacqueline Alblas
    Tissue Engineering, Part A
    We found no differences in efficiency by using BMP-2 plasmid DNA or any of the BMP-2 protein dosages. Therefore we conclude that BMP-2 plasmid DNA based gene therapy in alginate is ...
  • Transgene Expression up to 7 years in Nonhuman Primates Following...
    Nicola Brunetti-Pierri, Thomas Ng, David Iannitti, William Cioffi, Gary Stapleton, Mark Law, John Breinholt, Donna Palmer, Nathan Grove, Karen Rice, Casssondra Bauer, Milton Finegold, Arthur Beaudet, Charles Mullins, Philip Ng
    Human Gene Therapy and Part B: Methods
    Transgene Expression up to 7 years in Nonhuman Primates Following Hepatic Transduction with Helper-Dependent Adenoviral Vectors Human Gene Therapy and Part B: Methods ...
  • Tat-PTD-modified Oncolytic Adenovirus Driven by the SCG3 Promoter...
    Chuan Jin, Di Yu, Matko Cancer, Berith Nilsson, Justyna Leja, Magnus Essand
    Human Gene Therapy and Part B: Methods
    Tat-PTD-modified Oncolytic Adenovirus Driven by the SCG3 Promoter and ASH1 Enhancer for Neuroblastoma Therapy Human Gene Therapy and Part B: Methods Secretogranin III (SGC3) ...

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