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  • Elan Bets $1B on Theravance/GSK Respiratory Drugs
    Muscarinic Antagonist-Beta2 Agonist) monotherapy (GSK961081/MABA '081), and VI monotherapy, all developed through the LABA collaboration with GSK-when, as, and if received. ...
    5-13-2013
  • Companion Diagnostics: 52 Pick-Up
    ... Thermo Fisher Scientific) and GlaxoSmithKline Agreement announced October 25, 2011 Collaboration designed to develop a companion diagnostic to a GSK candidate cancer immunotherapy. ...
    5-9-2013
  • GSK Parts Ways with Impax
    in which GSK has rights to commercialize the product,' Impax said in a statement. ... The 2010 agreement called for Impax to manufacture and supply IPX066 to GSK. In return, ...
    4-29-2013
  • Avalon Ventures to Fund up to 10 Life Science Startups in Collaboratio...
    areas, which a joint management committee of Avalon and GSK will then approve. From there, Avalon and GSK will finance these new technologies - and newly-established ...
    4-23-2013
  • Stem Cell Screen Reveals Promising Target for ALS
    motor neurons was kenpaullone, previously known for blocking the action of the enzyme GSK-3, which switches on and off several cellular processes including cell growth and death. ...
    4-19-2013
  • GSK Sells Rights to Market Breast Cancer Drug in China
    Chinese specialty pharmaceutical company Eddingpharm is collaborating with GlaxoSmithKline China (GSK) to acquire from GSK the exclusive right in mainland China to import, market, ...
    4-9-2013
  • Mystery Rare Disease Drug Earns Isis $5M from GSK
    (GSK) toward the development of a drug to treat an undisclosed rare and serious disease. Isis will develop the drug to Phase II proof-of-concept, at which time GSK has the ...
    2-19-2013
  • Not Quite 1918, but Flu Still Deadly
    ... in a position to take new orders for Fluarix or FluLaval for this year's flu season," GSK spokesman Rob Perry told GEN. "We are fulfilling existing orders from our U.S. ...
    2-15-2013
  • Type 2 Diabetes Drugs Drive Sector Growth
    ... U.S. and EU filings are expected in 2013. GlaxoSmithKline (GSK) also has an SGLT-2 ... The company plans to file for marketing approval in the first quarter of 2013. GSK is ...
    2-1-2013
  • Not Quite 1918, but Flu Still Deadly
    ... in a position to take new orders for Fluarix or FluLaval for this year's flu season," GSK spokesman Rob Perry told GEN. "We are fulfilling existing orders from our U.S. ...
    1-21-2013
  • Top 10 Biggest Biopharma Marketing Fines
    ... of the Admissions and Resulting Penalties: GSK pleaded guilty to two counts of introducing ... report safety data about Avandia to FDA. GSK also agreed to pay $1 billion consisting of ...
    1-21-2013
  • Galapagos Deals Aim to Shore Up Drug Discovery
    oncology diseases. The Zagreb research center's staff of 100 has worked to develop new drugs for GSK-which bought the former Pliva Research Institute in 2006-as well as Galapagos. ...
    1-15-2013
  • The New Economics of Orphan Diseases
    ... GSK also has partnered with JCR Pharmaceuticals, Isis Pharmaceuticals, Fondazione ... A 250-patient trial by previous sponsor GSK narrowly missed its endpoint. Adventrx is ...
    1-1-2013
  • GSK Teams with GlycoVaxyn on New Bacterial Vaccines
    Biologicals (GSK) to develop new bacterial vaccines employing GlycoVaxyn's bioconjugation technology. The agreement includes a set of pathogen targets. GSK will have the ...
    12-19-2012
  • Drug Companies Exert Greater Influence on Development
    ... Last July, in a civil settlement agreement, the United States alleged that GSK promoted ... It also alleged that GSK stated that Avandia had a positive cholesterol profile despite ...
    12-5-2012
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    Journal Articles

  • Commitment of Mouse Embryonic Stem Cells to the Adipocyte Lineage...
    Miguel C. Monteiro, Brigitte Wdziekonski, Phi Villageois, Cecile Vernochet, Catherine Iehle, Nathalie Billon, Christian Dani
    Stem Cells and Development
    Retinoic Acid Receptor β and Active GSK3 Stem Cells and Development Key events ... We show that pharmacological inhibitors of glycogen synthase kinase (GSK) 3, completely ...
  • Secreted Frizzled Related Protein 4 Reduces Fibrosis Scar Size...
    Kentaro Matsushima, Takashi Suyama, Chiemi Takenaka, Naoki Nishishita, Keiko Ikeda, Yoshito Ikada, Yoshiki Sawa, Lars Martin Jakt, Hajime Mori, Shin Kawamata
    Tissue Engineering, Part A
    Increased amounts of both the inactive serine 9-phosphorylated form of glycogen syntase kinase (GSK)-3ß and the active form of ß-catenin were observed by immunohistology 3 days ...
  • Human Sarcopenia Reveals an Increase in SOCS-3 and Myostatin...
    Bertrand Léger, Wim Derave, Katrien De Bock, Peter Hespel, Aaron P. Russell
    Rejuvenation Research
    hypertrophy, including GH/STAT5, IGF-1/Akt/GSK-3ß/4E-BP1, and muscle atrophy, including ... Phosphorylated and total GSK-3ß were increased by 1.5 and 1.8 fold, respectively, while ...
  • Erythropoietin Increases the Motility of Human Bone Marrow-Multipotent...
    Seong-Ho Koh, Min Young Noh, Goang Won Cho, Kyung Suk Kim, Seung Hyun Kim
    Stem Cells and Development
    Immunoblotting assays revealed increased expression of phospho-Akt, phospho-GSK-3ß, phospho-extracellular signal-regulated kinase (ERK), ß PAK-interacting exchange factor (PIX), ...

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Genome Sequencing and Patient Autonomy

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