Current Issue

View Larger Image

Past Issues Free Subscriptions
Sponsored
Keywords



Search Results - Fibroblasts
 More »

  • A First: hESCs Generated from Somatic Cells
    fact differentiate into any cell type, and inherited their nuclear genomic content exclusively from the nuclear donor fibroblasts with no detectable contribution of oocyte alleles. ...
    5-14-2013
  • Literature Review: A Step Closer to Personalized Medicine
    Note that after 19 days in the absence of HAT media (F), fibroblasts have overgrown the ... modified mouse allows the noncancer fibroblasts of the human patient to be replaced by ...
    5-14-2013
  • Study: Protein Secreted by Certain Fat Cells Can Trigger RA
    The study, "Roles of Adipocytes and Fibroblasts in Activation of the Alternative Pathway ... on May 6. Roles of Adipocytes and Fibroblasts in Activation of the Alternative ...
    5-8-2013
  • The Tumor Microenvironment as a Drug Target, Part II
    Cancer-associated fibroblasts (CAFs) comprise most of the bulk of cancer stroma, affecting ... cancer stroma and normal breast fibroblasts could be stratified based on tumor subtypes. ...
    5-7-2013
  • Protein Complex Mutated in about 20% of All Cancers
    In a previous paper in Nature, the team reported that switching subunits within BAF complexes can convert human fibroblasts to neurons, which points to their instructive role in ...
    5-6-2013
  • Biologically Relevant Laminins
    When mature cells are placed in vitro for culture, they often de-differentiate within hours to days into other cell types, such as fibroblasts. In this article I will discuss the ...
    5-1-2013
  • The Tumor Microenvironment as a Drug Target: Chasing Slippery...
    These include normal host cells such as endothelial cells, fibroblasts, mesenchymal cells, ... on tumor-associated fibroblasts and other mesenchymal stromal cells in epithelial tumors. ...
    5-1-2013
  • Direct DNA Sequencing Using Nanopore Sensors
    ... Lange and her colleagues determined the fate of telomeres lacking one or more of the six shelterin subunits by using Cre-mediated conditional deletion in mouse embryo fibroblasts. ...
    4-1-2013
  • Epigenetics Opens New Avenues for DNA Research
    ... to reprogram terminally differentiated fibroblasts into induced pluripotent stem (iPS) ... This was first reported in 2006 for mouse fibroblasts and in 2007 for human fibroblasts, ...
    4-1-2013
  • Medicine: Getting Personal
    ... in place to produce its recently approved Gentuit(tm) product, composed of allogeneic human keratinocytes and fibroblasts, for oral tissue regeneration around teeth and implants. ...
    3-15-2013
  • Lab Automation Sparks Creativity
    ... the HCS platform to identify potential cellular toxicity pathways. Primary embryo fibroblasts isolated from 32 genetically characterized inbred mouse strains were exposed in ...
    1-1-2013
  • iPS Cells: Where We Started and Where We're Going
    ... Using this method, they identified four genes, (Oct3/4, Sox2, c-Myc, and Klf4, a.k.a., the Yamanaka factors 4 ) that could turn fibroblasts, or other somatic cells into induced ...
    12-5-2012
  • Multiplexed Drug Assessment in 3D
    ... line (HCT-116) and mouse embryonic fibroblasts (NIH3T3): The cancer cell population is ... expressing a green fluorescent (C) and the fibroblasts a red fluorescent protein (F). ...
    12-1-2012
  • iPSCs Reveal Somatic Copy Number Mosaicism in Skin Cells
    two CNVs that were not apparent in the fibroblasts from which the iPSC was derived. ... somatic genomic variants in parental fibroblasts-that is, the fibroblasts from which ...
    11-20-2012
  • Purified Chondrocytes from iPSCs Repair Cartilage
    They first prompted mouse tail fibroblasts to reprogram into iPSCs using a previously described approach of forcing the overexpression of four transcription factors, Oct4, Sox3, ...
    10-30-2012
  • More »

    Journal Articles

  • Long-Term Spatially Defined Coculture Within Three-Dimensional...
    Taymour M. Hammoudi, Hang Lu, Johnna S. Temenoff
    Tissue Engineering, Part C: Methods
    This technique was further applied for spatially controlled patterning of primary tendon/ligament fibroblasts and marrow stromal cells in a single 1.5-mm-thick laminated hydrogel ...
  • Dermagraft: Use in the Treatment of Chronic Wounds
    Charles E. Hart, Andrea Loewen-Rodriguez, Jan Lessem
    Advances in Wound Care
    culture of neonatal dermal fibroblasts onto a bioabsorbable polyglactin mesh scaffold. During the product-manufacturing process, the human fibroblasts proliferate to fill the ...
  • Laser Printing of Skin Cells and Human Stem Cells
    Lothar Koch, Stefanie Kuhn, Heiko Sorg, Martin Gruene, Sabrina Schlie, Ralf Gaebel, Bianca Polchow, Kerstin Reimers, Stephanie Stoelting, Nan Ma, Peter M. Vogt, Gustav Steinhoff, Boris Chichkov
    Tissue Engineering, Part C: Methods
    In the current study, skin cell lines (fibroblasts/keratinocytes) and human mesenchymal stem cells (hMSC) were chosen for laser printing experiments due to their high potential in ...
  • Fenestration Defects in the Rabbit Jaw: An Inadequate Model for...
    Daniel A.W. Oortgiesen, Gert J. Meijer, Antonius L.J.J. Bronckers, X. Frank Walboomers, John A. Jansen
    Tissue Engineering, Part C: Methods
    Apparently, the new PDL originates from mesenchymal cells that arise from the apical part (sheath of Hertwig) and subsequently developed into PDL fibroblasts. At 12 weeks, no signs ...

GEN Webinars

View »

GEN Web Briefs

View »

GEN Poll

More » Poll Results » Archive »

Genome Sequencing and Patient Autonomy

Do you think ACMG’s recent recommendations for reporting incidental clinical sequencing results undermine patient autonomy?

Suggest a Poll