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Search Results - Fibroblasts
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  • New RNA-Based Method for Producing iPSCs
    While terminally differentiated somatic cells such as fibroblasts can be reprogrammed to ... A single VEE-RF RNA transfection into newborn or adult human fibroblasts resulted in ...
    8-1-2013
  • No "Master Genes" Needed: Scientists Generate iPSCs with Small...
    It was considered a major breakthrough when scientists first transformed adult fibroblasts ... GFP expression mouse embryonic fibroblasts with viral expression of Sox2, Klf4, ...
    7-19-2013
  • Gene Editing to Treat Genetic Diseases, Part II
    ... This led to restoration of dystrophin protein expression in cells from DMD patients, including skeletal myoblasts and dermal fibroblasts that were reprogrammed to the myogenic ...
    6-20-2013
  • A First: hESCs Generated from Somatic Cells
    fact differentiate into any cell type, and inherited their nuclear genomic content exclusively from the nuclear donor fibroblasts with no detectable contribution of oocyte alleles. ...
    5-14-2013
  • Literature Review: A Step Closer to Personalized Medicine
    Note that after 19 days in the absence of HAT media (F), fibroblasts have overgrown the ... modified mouse allows the noncancer fibroblasts of the human patient to be replaced by ...
    5-14-2013
  • Study: Protein Secreted by Certain Fat Cells Can Trigger RA
    The study, "Roles of Adipocytes and Fibroblasts in Activation of the Alternative Pathway ... on May 6. Roles of Adipocytes and Fibroblasts in Activation of the Alternative ...
    5-8-2013
  • The Tumor Microenvironment as a Drug Target, Part II
    Cancer-associated fibroblasts (CAFs) comprise most of the bulk of cancer stroma, affecting ... cancer stroma and normal breast fibroblasts could be stratified based on tumor subtypes. ...
    5-7-2013
  • Protein Complex Mutated in about 20% of All Cancers
    In a previous paper in Nature, the team reported that switching subunits within BAF complexes can convert human fibroblasts to neurons, which points to their instructive role in ...
    5-6-2013
  • Biologically Relevant Laminins
    When mature cells are placed in vitro for culture, they often de-differentiate within hours to days into other cell types, such as fibroblasts. In this article I will discuss the ...
    5-1-2013
  • The Tumor Microenvironment as a Drug Target: Chasing Slippery...
    These include normal host cells such as endothelial cells, fibroblasts, mesenchymal cells, ... on tumor-associated fibroblasts and other mesenchymal stromal cells in epithelial tumors. ...
    5-1-2013
  • Direct DNA Sequencing Using Nanopore Sensors
    ... Lange and her colleagues determined the fate of telomeres lacking one or more of the six shelterin subunits by using Cre-mediated conditional deletion in mouse embryo fibroblasts. ...
    4-1-2013
  • Epigenetics Opens New Avenues for DNA Research
    ... to reprogram terminally differentiated fibroblasts into induced pluripotent stem (iPS) ... This was first reported in 2006 for mouse fibroblasts and in 2007 for human fibroblasts, ...
    4-1-2013
  • Medicine: Getting Personal
    ... in place to produce its recently approved Gentuit(tm) product, composed of allogeneic human keratinocytes and fibroblasts, for oral tissue regeneration around teeth and implants. ...
    3-15-2013
  • Lab Automation Sparks Creativity
    ... the HCS platform to identify potential cellular toxicity pathways. Primary embryo fibroblasts isolated from 32 genetically characterized inbred mouse strains were exposed in ...
    1-1-2013
  • iPS Cells: Where We Started and Where We're Going
    ... Using this method, they identified four genes, (Oct3/4, Sox2, c-Myc, and Klf4, a.k.a., the Yamanaka factors 4 ) that could turn fibroblasts, or other somatic cells into induced ...
    12-5-2012
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    Journal Articles

  • miR-205 hinders the malignant interplay between prostate cancer...
    Paolo Gandellini, Elisa Giannoni, Anna Casamichele, Maria Letizia Taddei, Maurizio Callari, Claudia Piovan, Riccardo Valdagni, Marco Alessandro Pierotti, Nadia Zaffaroni, Paola Chiarugi
    Antioxidants & Redox Signaling
    miR-205 hinders the malignant interplay between prostate cancer cells and associated fibroblasts Antioxidants & Redox Signaling
  • Characterization of total and active matrix metalloproteinases...
    Erik Attia, Krista Bohnert, Haydee Brown, Madhu Bhargava, Jo Hannafin
    Tissue Engineering, Part A
    Characterization of total and active matrix metalloproteinases 1, 3 and 13 synthesized and secreted by ACL fibroblasts in 3D collagen gels Tissue Engineering, Part A
  • Corneal stromal cell plasticity: in vitro regulation of cell...
    Samantha Louise Wilson, Ying Yang, Alicia J El Haj
    Tissue Engineering, Part A
    Corneal stromal cells were activated to their injury phenotype (fibroblasts) and expanded before being encapsulated in type-I collagen hydrogels constructs. Three different ...
  • Natural Corneal Cell-based Microenvironment as Prerequisite for...
    Simon Schulz, David Beck, Dougal Laird, Thorsten Steinberg, Pascal Tomakidi, Thomas Reinhard, Philipp Eberwein
    Tissue Engineering, Part C: Methods
    cornea-derived in vivo-like cell microenvironment, together with immortalized stromal fibroblasts alone (non-holistic) or fibroblasts and immortalized endothelial cells (holistic). ...

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