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Search Results - FRET
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  • HTRF Applications in New Drug Discovery
    as G protein-coupled receptors (GPCRs), kinases, and biomarkers. "HTRF brings fluorescent resonance energy transfer technology (FRET) together with time-resolved measurement (TR). ...
    7-1-2013
  • Lights, Camera, and Lots of Cellular Action
    ... resonance energy transfer (FLIM-FRET) multiwell plate reader based on time-gated imaging. ... investigating the application of FLIM and FRET to read out biomolecular interactions in ...
    6-1-2013
  • Potential Prion Disease Therapy Uncovered
    The two compounds are already marketed as the drugs tacrolimus and astemizole. The team developed a screening technique, the PrP-FRET-enabled high-throughput assay (PrP-FEHTA), to ...
    4-4-2013
  • Illuminating Human DNA Replication
    To test this hypothesis, the team of researchers used Förster resonance energy transfer (FRET), a technique of attaching fluorescent tags to human proteins and sections of DNA in ...
    4-2-2013
  • 8 Reasons Labs Rely on Digital and Quantitative PCR
    Researchers can select from intercalating dyes (such as SYBR green) to a variety of target-specific probes (TaqMan, molecular beacons, and FRET, for example). qPCR also affords ...
    2-7-2013
  • En Bloc Analysis of Epigenetic Publications
    ... In addition, Figure 3A shows that certain analytical techniques such as FRET, pyro-sequencing, and Sanger sequencing are growing rapidly. Figure 3B shows most cancer segments are ...
    2-1-2013
  • Look, No Label! Label-Free MST
    on the performance on reporting K a and K d between SPR and a TR-FRET based assay (LanthaScreen Eu kinase binding assay; Mason et al. , Assay Drug Dev Technol 2012;10:468-475). ...
    12-31-2012
  • For DNA, the Fix Is In
    Dr. Ha's research team used fluorescence resonance energy transfer (FRET) to observe in real time the interaction of the RecA protein and the DNA. Researchers labeled a single DNA ...
    12-14-2012
  • Close-Up View of Life Science Microscopy
    ... to co-localize two molecules to see if they are interacting, you need to have supplementary techniques like FRET at the nanometer scale to confirm that they are interacting." ...
    12-1-2012
  • Super-Resolution Imaging Camera
    GSD. The camera is also suited for a range of other applications including SMF and tracking, live-cell spinning-disk confocal, SPIM, intrinsic imaging, FCWS, TIRF, FRET, and FRAP.
    12-1-2012
  • ATP Gets Smart/Absorbing BLA Assay
    The bla enzyme is a commonly used reporter in cell-based assays in which a fluorescence-resonance-energy-transfer (FRET) substrate is used to measure activity. The FRET substrate ...
    11-2-2012
  • Peering into Subcellular Domains
    transfer (FRET), a single molecule technology in which energy is transferred from an excited molecular fluorophore (the donor) to another fluorophore (the acceptor). "FRET is ...
    11-1-2012
  • Firms Collaborate on Small Molecule GPCR Drugs
    The technology involves establishing a FRET binding assay between the targeted receptor fused to GFP and a fluorescent ligand selected from Domain's library of GPCR frequent hitter ...
    10-23-2012
  • CCD Cameras
    for immunofluorescence and fluorescent protein imaging. The cameras are also well suited for near-infrared DIC, electrophysiology, particle tracking, and FRET and FRAP imaging.
    10-15-2012
  • DRSG Sequencing Troubleshooting Web Resource
    Yet, just like any other technique, DNA sequencing comes with its own set of technical hiccups that demand troubleshooting by the researcher. Luckily, researchers need not fret and ...
    9-15-2012
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    Journal Articles

  • A Time-Resolved Fluorescence Resonance Energy Transfer Assay...
    Yuhong Du, Robert W. Fu, Bin Lou, Jing Zhao, Min Qui, Fadlo R. Khuri, Haian Fu
    ASSAY and Drug Development Technologies
    fluorescence resonance energy transfer (TR-FRET) assay to detect the interaction of 14-3-3 ... Through a series of titration studies in which europium-labeled 14-3-3 serves as a FRET ...
  • Early Detection of Trichinella spiralis in Muscle of Infected...
    Chairat Tantrawatpan, Pewpan M. Intapan, Tongjit Thanchomnang, Oranuch Sanpool, Penchom Janwan, Thidarut Boonmars, Nimit Morakote, Wanchai Maleewong
    Vector-Borne and Zoonotic Diseases
    Vector-Borne and Zoonotic Diseases Real-time fluorescence resonance energy transfer (FRET) PCR and melting curve analysis using newly developed fluorophore-labeled hybridization ...
  • In Pursuit of Synthetic Modulators for the Orphan Retina-Specific...
    Qiong Qin, Anna Knapinska, Nicoleta Dobri, Franck Madoux, Peter Chase, Peter Hodder, Konstantin Petrukhin
    Journal of Ocular Pharmacology and Therapeutics
    The time-resolved fluorescence energy transfer (TR-FRET) assay assessing agonist-sensitive ... A counterscreen TR-FRET assay that measures the affect of test compounds on PPAR? ...
  • High-Throughput Tracking of Pluripotent Human Embryonic Stem...
    Frank W. King, Walter Liszewski, Carissa Ritner, Harold S. Bernstein
    Stem Cells and Development
    transfer (FRET) molecular beacon system using fluorescence-activated cell sorting (FACS) with Oct4 as a target. We demonstrate that Oct4 can be detected by FRET using confocal ...

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