Current Issue

View Larger Image

Past Issues Free Subscriptions
Sponsored
Keywords



Search Results - Enzymes
 More »

  • Heightened Characterization of Therapeutic mAbs Using a Novel...
    This approach reduces the number of fragments generated by conventional enzymes, limits digestion variability, and minimizes the generation of method-induced degradation products ...
    5-15-2013
  • Seasoned Drugs Offer Therapeutic Gold Mine
    ... Another repositioned drug, commonly used in Africa for sleeping sickness, was a failed cancer drug from the 1980s. Both cancer drugs target the same class of enzymes, decarboxylase ...
    5-15-2013
  • BASF Using Dyadic Technology for New Enzymes in $6M+ Deal
    produce, distribute and sell industrial enzymes for animal and human nutrition among ... that enables development and large-scale manufacture of low-cost proteins and enzymes. ...
    5-15-2013
  • Fluorescence Lifetime Assays
    ... Figure 2A. FLEXYTE isopeptide-DUB assay principle. There is a growing interest in targeting the deubiquitylating family of enzymes (DUBs) for drug discovery, given their increasing ...
    5-15-2013
  • Making Vaccines from Parts
    The genetic code turned out to be a strain of the avian influenza H7N9. The researchers used enzymes to assemble synthetic DNA into genes and then corrected errors in the resulting ...
    5-14-2013
  • AbbVie, Alvine Make $70M Celiac Disease Drug Deal
    The treatment in question, ALV003, is an investigational oral therapy composed of two recombinant, gluten-specific enzymes-a cysteine protease (EP-B2) and a prolyl endopeptidase ...
    5-14-2013
  • Merck Launches Up To $430M Diabetes Collaboration with Abide
    Serine hydrolases comprise a family of enzymes that play a role in human physiological processes. They include regulating CNS signaling, digestion, metabolism, inflammation, blood ...
    5-2-2013
  • Ligand Buys Potential Milestone/Royalty Portfolio in Up To $4...
    ... effort, and costs associated with developing high-performance mammalian cell lines for therapeutic protein production, such as monoclonal antibodies, growth factors, and enzymes. ...
    4-30-2013
  • Single-Use Bioreactor Roundup
    ... Optimizing facilities, especially for multipurpose/product manufacturing, personalized medicine, e.g., cell therapy (T-Cell expansion), unique recombinant "eplacement enzymes or ...
    4-15-2013
  • Hand-Held Homogenization Tool
    Due to the absence of additional substances such as enzymes, detergents, or corrosives, mechanical sample lysis is the preferred process for use in the preparation of ...
    4-15-2013
  • Thermo Fisher's (Mostly) Buying Spree
    ... July 16, 2010 - Completes $260 million acquisition of Fermentas International, a maker of reagents, enzymes, and kits with about 500 employees, and 2009 revenues of C$57 million ...
    4-15-2013
  • Agios Lays the Foundation on New Cancer Metabolism Programs
    The programs focus on developing new cancer metabolism inhibitors targeting tumors carrying mutations in either the IDH1 or IDH2 metabolic enzymes. The companies are collaborating ...
    4-4-2013
  • Illuminating Human DNA Replication
    The sliding clamp then serves to anchor special enzymes called polymerases to the DNA, ensuring efficient copying of the genetic material. "Without a sliding clamp, polymerases can ...
    4-2-2013
  • Direct DNA Sequencing Using Nanopore Sensors
    ... through the nanopores is via the use of enzymes such as DNA polymerases, which are ... Again, without any processive enzymes, the DNA molecules move too fast to perform a direct ...
    4-1-2013
  • Predicting Drug Toxicity in Humans
    ... Boriss. "Measuring the induction of drug metabolizing enzymes with mRNA expression ... It is well known that some drugs inhibit one or more of the drug metabolizing enzymes such ...
    4-1-2013
  • More »

    Journal Articles

  • Elevated Liver Enzymes in Metabolic Syndrome Are Associated with...
    Jihène Rejeb, Asma Omezzine, Imen Boumaiza, Lamia Rebhi, Kchock Kaouthar, Nesrine Kalboussi, Nabila Ben Rejeb, Naoufel Nabli, Ahmed Ben Abdelaziz, Essia Boughzala, Ali Bouslama
    Metabolic Syndrome and Related Disorders
    Elevated Liver Enzymes in Metabolic Syndrome Are Associated with Coronary Stenosis in a ... Abstract Background: Recently, elevated liver enzymes have attracted great interest as ...
  • Phage Endolysins with Broad Antimicrobial Activity Against Enterococcu...
    Daniela Proença, Sofia Fernandes, Clara Leandro, Filipa Antunes Silva, Sofia Santos, Fátima Lopes, Rosario Mato, Patrícia Cavaco-Silva, Madalena Pimentel, Carlos São-José, Carlos Sao-Jose
    Microbial Drug Resistance
    Phage Endolysins with Broad Antimicrobial Activity Against Enterococcus faecalis Clinical Strains Microbial Drug Resistance Increasing antibiotic resistance of bacterial pathogens ...
  • Calcium-Dependent Complex Formation Between PBP2 and Lytic Transglycos...
    Ioulia Nikolaidis, Thierry Izoré, Viviana Job, Nicole Thielens, Eefjan Breukink, Andréa Dessen, Thierry Izore, Andrea Dessen
    Microbial Drug Resistance
    requires the coordinated action of enzymes and structural proteins located in the ... Their action is coordinated with that of other enzymes essential for cell-wall ...
  • The Lytic Transglycosylases of Neisseria gonorrhoeae
    Yolande A. Chan, Kathleen T. Hackett, Joseph P. Dillard
    Microbial Drug Resistance
    These peptidoglycan (PG)-degrading enzymes are required for a number of processes that are ... Here, we review the information available on these enzymes and discuss their roles in ...

GEN Webinars

View »

GEN Web Briefs

View »

GEN Poll

More » Poll Results » Archive »

Genome Sequencing and Patient Autonomy

Do you think ACMG’s recent recommendations for reporting incidental clinical sequencing results undermine patient autonomy?

Suggest a Poll