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  • Protein Linked to Alzheimer's-Like Symptoms Identified
    The work focused on eukaryotic initiation factor-2alpha (eIF2alpha) and two enzymes that ... examined the neurological impact of two enzymes that phosphorylate eIF2alpha, kinases ...
    8-12-2013
  • Math Casts New Light on Long-Studied Biological Process
    the level of cAMP and the level of enzymes that break down sugar molecules in ... Hwa. "The levels of the sugar uptake and utilization enzymes lined up remarkably into two ...
    8-7-2013
  • Don't Call It "Junk DNA" Anymore
    This was related to the levels of the enzymes needed to chop out the intron. Unless the intron is excised, functional protein products are never produced from these genes. The ...
    8-5-2013
  • Newly Found Protein Modification May Play a Role in Cancer and...
    Moellering soon found it: on other glucose-metabolizing enzymes, as well as on proteins ... occurs on glucose-metabolizing enzymes, it tends to inhibit their activities, ...
    8-2-2013
  • Just How Versatile Is the Polymerase Chain Reaction?
    ... This evolutionary approach can be expanded to other enzymes that can be linked in some way to PCR. Ironically, this self-evolution will enable PCR to remain a major player in the ...
    7-25-2013
  • Marblar Challenges GEN Readers to Find New Uses for "Super-Biotin...
    the fact that the linker between the biotin and compound is very sensitive to certain enzymes, a problem that a group from the University of Edinburgh has just solved: They have ...
    7-24-2013
  • RT-PCR: Ready for Prime Time?
    ... The team used this novel approach to study antibiotic resistance of gram negative bacteria. Mutations in beta lactamase enzymes give rise to an extended spectrum of antibiotic ...
    7-23-2013
  • Immobilized Enzymes Focus of Purolite, Codexis Partnership
    enzymes for the pharmaceutical industry. Pennsylvania-based firm Purolite manufactures ion exchange, catalyst, adsorbent, and specialty resins; Codexis engineers enzymes for ...
    7-16-2013
  • Forma, Cancer Research UK in DUBs Drug Discovery Collaboration
    and therapeutic candidates against a variety of deubiquitinating enzymes, or DUBs. ... Together, the organizations aim to investigate the protease enzymes that regulate ...
    7-9-2013
  • The Best Science Apps
    The "useful stuff" section contains text descriptions of pertinent enzymes and other aspects of DNA replication such as leading and lagging strands and Okazaki fragments. Due to ...
    7-8-2013
  • 4 Steps to Get Your ChIP Experiment Working
    For X-ChIP sonication is necessary as formaldehyde cross-linking restricts the access of enzymes to their targets. Sonication creates random DNA fragments (average of 500-700 bp). ...
    7-2-2013
  • Targeting Deranged Metabolism to Treat Cancer
    But in the last few years, scientists have identified mutant forms of enzymes peculiar to ... to an altered metabolite profile, as the enzymes function "at a crossroads of cellular ...
    7-1-2013
  • OnScreen DNA Replication
    The "useful stuff" section contains text descriptions of pertinent enzymes and other aspects of DNA replication such as leading and lagging strands and Okazaki fragments. Due to ...
    7-1-2013
  • Synthetic Biology May Protect Your Food This Summer
    We are now able to engineer the coding genes for luminescent enzymes much more easily into the phages." There have been numerous conferences along with much discussion about the ...
    6-25-2013
  • The 11 Golden Rules of Working with Proteomic Samples
    ... Enzymatic activity will resume in frozen samples once thawed, resulting in further change especially since membrane integrity may have been lost, allowing enzymes access to new ...
    6-21-2013
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    Journal Articles

  • Multi-omics Approach for Estimating Metabolic Networks Using...
    Mitsunori Kayano, Seiya Imoto, Rui Yamaguchi, Satoru Miyano
    Journal of Computational Biology
    use of protein and transcript data of enzymes improved the accuracy of the estimated ... investigated the role of metabolites and enzymes that were identified as important factors ...
  • Ocimum sanctum Linn. (Holy Basil) Ethanolic Leaf Extract Protects...
    P. Manikandan, R. Senthil Murugan, H. Abbas, S.K. Abraham, S. Nagini
    Journal of Medicinal Food
    Leaf Extract Protects Against 7,12-Dimethylbenz[ a ]Anthracene-Induced Genotoxicity, Oxidative Stress, and Imbalance in Xenobiotic-Metabolizing Enzymes Journal of Medicinal Food
  • CYP1A1 Gene Polymorphisms and Polycystic Ovary Syndrome Risk...
    Wenjing Shen, Tianren Li, Yanjie Hu, Hongbo Liu, Min Song
    Genetic Testing and Molecular Biomarkers
    Aims: Emerging evidence suggests that common functional polymorphisms in the CYP1A1 gene are involved in the regulation of the activities of cytochrome P450 enzymes, thereby ...
  • Human β-glucuronidase: Structure, Function and Application in...
    Huma Naz, Asimul Islam, Abdul Waheed, Faizan Ahmad, William S Sly, MD IMTAIYAZ HASSAN
    Rejuvenation Research
    of macromolecules by various hydrolytic enzymes in the lysosome. Despite of structural differences, most of the lysosomal enzymes share many common features including ...

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