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Search Results - Drug Resistance
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  • Deciphering RNA Secondary Structure
    F.J. Le Grice, Ph.D., a researcher who holds senior positions at both the HIV Drug Resistance Program and the Center for Cancer Research. "Similar to its HIV-1 counterpart, ...
    10-15-2013
  • Growing and Preparing Adult Stem Cells
    ... a defective gene, conveying pathogen resistance, or making the cells able to withstand ... that with multiple rounds of treatment the drug is toxic to the hematopoietic stem cell ...
    10-15-2013
  • Accelerating Precision Medicine with Efficient Drug Sensitivity...
    Recently identified associations between variants of cancer genes and drug resistance have increased the value for comprehensive drug sensitivity screening in combination with ...
    10-2-2013
  • Takeover Targets: Who Is First on the List?
    ... cKIT inhibitor targeting resistance mutations for gastrointestinal stromal tumors (GIST). ... of Jakafi for myelofibrosis, with the drug generating $102.4 million for the first ...
    9-24-2013
  • Striking Solid Tumors: Transporting Treatments Safely and Effectively
    ... Moreover, certain types of nanoparticles have showed some interesting capacity to reverse multiple-drug resistance, which is a major problem in chemotherapy. Meanwhile, ...
    9-23-2013
  • Cutting Melanoma Off at the Pass
    ... According to the Wistar scientist, "we now we have a mechanism and a rational approach to develop both new drugs and more effective combinations aimed at solving drug resistance in ...
    9-20-2013
  • Scientists Devise Shortcut for Finding New Antibiotics
    "Some bacteria have evolved resistance to every known class of antibiotic and, when these multi-drug resistant bacteria cause an infection, they are nearly impossible to treat. ...
    9-17-2013
  • BEAMing for Cancer
    by selective pressures exerted by the host immune system and external drug treatments. ... well as for tracking the occurrence of resistance mutations during and after treatment, ...
    9-1-2013
  • Biopharmas Drive Antibiotic Development
    Of those, 86% were small to medium-sized enterprises. Policy Changes "Drug resistance is an important issue in drug development and makes antibiotic drugs relatively unusual. If ...
    9-1-2013
  • Leveraging Metabolites as Biomarkers for Personalized and Translationa...
    Estimates vary, but the time and cost of bringing a drug successfully to market at 12+ ... and commercialization of an innovative diagnostic to measure insulin resistance. ...
    8-29-2013
  • MRSA Bug Jumped from Cattle to Humans 40 Years Ago
    Only human strains of CC97 were able to resist the drug, which indicates that the bacteria acquired resistance after they crossed over into humans, presumably through exposure to ...
    8-14-2013
  • Pfizer, Sanford-Burnham Team Up on Obesity, Diabetes Target Research
    and Pfizer will team up to identify and validate new targets for drug discovery. ... for reducing insulin resistance in obesity and diabetes, the research institute said. ...
    8-13-2013
  • FDA Approves Viiv Healthcare's HIV-1 Treatment Tivicay
    The drug-which was used without a pharmacokinetic boosting agent-interferes with one of ... on treatment-experienced patients with resistance to multiple classes of HIV medicines, ...
    8-13-2013
  • Biopharmas Drive Antibiotic Development
    Of those, 86% were small to medium-sized enterprises. Policy Changes "Drug resistance is an important issue in drug development and makes antibiotic drugs relatively unusual. If ...
    8-9-2013
  • Molecular Imaging Driving Development
    ... This creates a low-resistance path to the intracellular milieu, enabling observation of ... automation should enable extraction of specific ion channel parameters for drug screening. ...
    8-1-2013
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    Journal Articles

  • Drug Resistance and Coreceptor Usage in HIV Type 1 Subtype C...
    Taryn N. Green, Mohendran Archary, Michelle L. Gordon, Nagavelli Padayachi, Yolanda Lie, Elizabeth D. Anton, Jacqueline D. Reeves, Anneke Grobler, Raziya Bobat, Hoosen Coovadia, Thumbi Ndung'u
    AIDS Research and Human Retroviruses
    Drug Resistance and Coreceptor Usage in HIV Type 1 Subtype C-Infected Children Initiating or Failing Highly Active Antiretroviral Therapy in South Africa AIDS Research and Human ...
  • Drug Resistance-Associated Genotypic Alterations in the pol Gene...
    Sunil K. Arora, Sachin Gupta, Jaideep S. Toor, Anuj Singla
    AIDS Research and Human Retroviruses
    Drug Resistance-Associated Genotypic Alterations in the pol Gene of HIV Type 1 Isolates in ART-Naive Individuals in North India AIDS Research and Human Retroviruses ABSTRACT We ...
  • Drug Resistance Mutations in Drug-Naive HIV Type 1 Subtype C...
    Vijay Bansode, Zuzanna J. Drebert, Simon A.A. Travers, Emmanuel Banda, Anna Molesworth, Amelia Crampin, Bagrey Ngwira, Neil French, Judith R. Glynn, Grace P. McCormack
    AIDS Research and Human Retroviruses
    Drug Resistance Mutations in Drug-Naive HIV Type 1 Subtype C-Infected Individuals from Rural Malawi AIDS Research and Human Retroviruses Abstract In this preliminary study we show ...
  • Drug Resistance Pattern of HIV Type 1 Isolates Sampled in 2007...
    Hannah O. Ajoge, Michelle L. Gordon, Sani Ibrahim, Oladapo S. Shittu, Thumbi Ndung'u, Stephen O. Olonitola
    AIDS Research and Human Retroviruses
    Drug Resistance Pattern of HIV Type 1 Isolates Sampled in 2007 from Therapy-Naive Pregnant Women in North-Central Nigeria AIDS Research and Human Retroviruses Abstract In Nigeria, ...

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