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Search Results - Drug Resistance
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  • Molecular Imaging Driving Development
    ... This creates a low-resistance path to the intracellular milieu, enabling observation of ... automation should enable extraction of specific ion channel parameters for drug screening. ...
    8-1-2013
  • FDA OKs Cepheid Combination TB, Drug Resistance MDx
    ... drug therapy." The U.S. Food and Drug Administration today granted marketing approval for Cepheid's Xpert MTB/RIF Assay. FDA OKs Cepheid Combination TB, Drug Resistance MDx
    7-26-2013
  • Pfizer Licenses Phase II TB Antibiotic Rights to Sequella
    resistance shown by existing therapies given the low natural resistance rate of M. tuberculosi s to either drug, their shortening of treatment time in animal TB models, and their ...
    7-17-2013
  • Federal Push to Fight Antibiotic Resistance
    a mechanism of resistance; or 3) have an alteration in the structure of the molecule that makes the drug no longer susceptible to the mechanism of resistance to existing drugs." ...
    7-15-2013
  • ADC, BZL Aim Warheads at PSMA-Positive Prostate Cancers
    One month after inking a deal with Genmab to develop a new antibody-drug conjugate (ADC) ... cancer therapies with fewer side effects and the potential to pre-empt resistance issues. ...
    7-15-2013
  • AstraZeneca Launches Cancer Collaborations
    that would allow clinicians to monitor tumor activity-including progression, response to therapy, and the onset of drug resistance-through blood tests and without biopsies. ...
    7-9-2013
  • Evotec Scores $1.9M Boehringer Milestone Payday
    to treat type 2 diabetes by targeting insulin resistance without causing weight gain. ... BI is one of several drug developers with which Evotec has long-term discovery alliances; ...
    7-8-2013
  • Basilea Wins Up to $89M BARDA Contract to Develop New Antibiotic
    and in special patient populations. "The drug has the potential of becoming an important ... BAL30072 addresses the global concerns of antibiotic resistance and also has a potential ...
    6-25-2013
  • Gene Editing to Treat Genetic Diseases, Part II
    involving PTC Therapeutics' small molecule drug candidate PTC124 (ataluren), which acts, ... to disease: dyslipidemia, insulin resistance, hypoglycemia, lipodystrophy, ...
    6-20-2013
  • T3D Licenses Drug Candidate from Dara, Repositions It for Alzheimer...
    insulin resistance / lowered cerebral glucose metabolism also are anticipated," Dr. Didsbury added. While T3D did not disclose the additional pathologies, several drug developers ...
    6-18-2013
  • Seeking New Tools Against Alzheimer's
    ... Amyloid: Path of Resistance A number of reasons explain why the amyloid pathway has proven resistant to a successful drug, according to Howard Fillit, M.D., executive director and ...
    6-7-2013
  • Metagenomics May Hold Key to Novel Antibiotic Discovery
    The approval came nearly two years after the FDA had rejected the drug for a second time ... derived from the environment, and to discover novel resistance genes in unexpected places. ...
    6-4-2013
  • Isis Wins $10M After AstraZeneca Adds Prostate Cancer Drug to...
    in patients with metastatic prostate cancer, as resistance to treatment develops. ISIS-AR Rx is the first drug to emerge from research into development under AstraZeneca's ...
    6-3-2013
  • Acquired Drug Resistance in Cancer
    say, reflects the complexity of the disease process coupled with an inability to properly guide the use of available therapeutics, and the development of tumor drug resistance. ...
    6-1-2013
  • Roswell Park Joins Jasco to Develop Lead Agent for Cancer
    signaling pathways, a major cause of resistance to frontline multiple myeloma ... research and director of RPCI's Center for Drug Development, said in a statement. "It's an ...
    5-31-2013
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    Journal Articles

  • Exploring the Contribution of Efflux on the Resistance to Fluoroquinol...
    Sunita Paltansing, Anouk Y. Tengeler, Margriet E.M. Kraakman, Eric C.J. Claas, Alexandra T. Bernards
    Microbial Drug Resistance
    Exploring the Contribution of Efflux on the Resistance to Fluoroquinolones in Clinical Isolates of Escherichia coli Microbial Drug Resistance Abstract Resistance to ciprofloxacin ...
  • Detection of Low-Frequency HIV-1 RT Drug Resistance Mutations...
    Herve Jacques Fleury, pantxika bellecave, Patricia Recordon-Pinson, jennifer papuchon, marie anne vandenhende, sandrine reigadas, brigitte tauzin
    AIDS Research and Human Retroviruses
    Detection of Low-Frequency HIV-1 RT Drug Resistance Mutations by Ultra-Deep Sequencing in Naïve HIV-1 Infected individuals AIDS Research and Human Retroviruses
  • Emergence of New Delhi metallo-β-lactamase 1 (NDM-1) Producing...
    Debdutta Bhattacharya, Ramanathan Thamizhmani, Haimanti Bhattacharya, Devarajan Sudharama Sayi, Nagarajan Muruganandam, Subarna Roy, Attayur Purushothaman Sugunan
    Microbial Drug Resistance
    Uropathogens Causing Urinary Tract Infections in Andaman Islands, India Microbial Drug Resistance The present study was undertaken to understand the distribution and the ...
  • Comparison of Antimicrobial Activity of Zinc Chloride and Bismuth...
    Javed Yakoob, Zaigham Abbas, Muhammad Waqas Usman, Safia Awan, Shagufta Naz, Fatima Jafri, Saeed Hamid, Wasim Jafri
    Microbial Drug Resistance
    Comparison of Antimicrobial Activity of Zinc Chloride and Bismuth Subsalicylate Against Clinical Isolates of Helicobacter pylori Microbial Drug Resistance We determined the in ...

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