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Search Results - Drug Discovery
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  • ELRIG Drug Discovery
    Manchester UNITED KINGDOM http://www.elrig.org/index.php/events/148-drug-discovery-2013/884-drug-discovery-2013
    9-2-2013
  • Drug Discovery Leaders' Summit
    Geneva SWITZERLAND http://www.drugdiscovery-summit1.com
    6-10-2013
  • Evotec, Harvard Go on Antibacterial Drug Hunt
    Using its drug discovery infrastructure and expertise in addressing antibacterial targets, Evotec will specifically target peptidoglycan biosynthesis (PGB). The approach, the firm ...
    5-16-2013
  • RuiYi Licenses mAb Development to China's Genor
    ... Headquartered in La Jolla, CA, RuiYi-which changed its name in October from Anaphore-carries out drug discovery in China, at the Zhangjiang Hi-Tech Park in Pudong, Shanghai. ...
    5-16-2013
  • Improving Proteomics Approaches
    ... Gräslund explained. "Rather, researchers use these molecules as starting points for drug discovery." The source of this molecular largesse is chemical libraries, whose access is ...
    5-15-2013
  • Moving Genomics Closer to the Clinic
    ... provide novel insights on which targeted drug or combination of drugs will show the most ... Researchers also reported discovery of a novel, recurrent KIF5B-RET gene fusion, which ...
    5-15-2013
  • Seasoned Drugs Offer Therapeutic Gold Mine
    ... Next they test those drugs against the parasites, and then use the drugs as a starting point for drug discovery. Dr. Pollastri calls it target class repurposing, in which a human ...
    5-15-2013
  • Mass Spec Provides Peek into PTMs
    ... to spatially profile proteins, lipids, drug, and small molecule metabolites in ... The field of degradomics, or protease substrate discovery, requires the newest techniques ...
    5-15-2013
  • Fluorescence Lifetime Assays
    ... As an illustration of this platform technology, FLEXYTE assays for two applications are outlined, one in the epigenetics field and the other in ubiquitin drug discovery. Figure 1B. ...
    5-15-2013
  • Highlights from AACR
    ... It allows for kidney function assessment as part of drug safety studies performed early in drug discovery and makes it possible to assess the efficacy of a drug candidate and its ...
    5-15-2013
  • RuiYi, CMC Collaborate to Speed mAb Development
    Headquartered in La Jolla, CA, RuiYi-which changed its name in October from Anaphore-carries out drug discovery in China at the Zhangjiang Hi-Tech Park in Pudong, Shanghai, using ...
    5-14-2013
  • Layoffs Imminent at Astellas: Two U.S. Labs to Close
    Some functions at the OSI and Perseid sites will be transferred to Astellas' Tsukuba Research Center, a 1.5 million-square-foot drug discovery research facility in Tsukuba City, ...
    5-14-2013
  • Forest Labs Bets Up To $460M on Trevena Heart Failure Drug
    potential of this promising compound, and further validates our biased ligand approach to GPCR drug discovery," Maxine Gowen, Trevena's president and CEO, said in the statement. ...
    5-9-2013
  • Companion Diagnostics: 52 Pick-Up
    ... diagnostic for use alongside erlotinib and Syndax' lead drug candidate entinostat. ... license agreement applying Metamark's discovery platform to identify and characterize ...
    5-9-2013
  • Nimbus, Shire Collaborate to Co-Develop Small Molecule Treatments
    Additional financial details of the agreement were not disclosed. "This collaboration validates our computationally-driven, structure-based drug discovery engine," Nimbus CSO ...
    5-8-2013
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    Journal Articles

  • Hepatic Differentiation of Human Embryonic Stem Cells Is Promoted...
    Toshio Miki, Alexander Ring, Jörg Gerlach
    Tissue Engineering, Part C: Methods
    The developmental potential of human embryonic stem cells (hESCs) holds great promise to provide a source of human hepatocytes for use in drug discovery, toxicology, hepatitis ...
  • Enrichment of Hepatocyte-like Cells with Upregulated Metabolic...
    Nripen S. Sharma, Eric J. Wallenstein, Eric Novik, Tim Maguire, Rene Schloss, Martin L. Yarmush
    Tissue Engineering, Part C: Methods
    The methodology described here to generate an enriched population of metabolically and functionally mature hepatocyte-like cells may have potential implications in drug discovery ...
  • Harnessing Systems Biology Approaches to Engineer Functional...
    Lauren S. Sefcik, Jennifer L. Wilson, Jason A. Papin, Edward A. Botchwey
    Tissue Engineering, Part B: Reviews
    how systems biology approaches have been applied to microvascular growth and remodeling, and how network analysis tools can be utilized to aid novel pro-angiogenic drug discovery.
  • Lengthened G1 Phase Indicates Differentiation Status in Human...
    Ashley Calder, Ivana Roth-Albin, Sonam Bhatia, Carlos Pilquil, Jong Hee Lee, Mick Bhatia, Marilyne Levadoux-Martin, Jamie McNicol, Jennifer Russell, Tony Collins, Jonathan S. Draper, Jong-Hee Lee, Jon S Draper
    Stem Cells and Development
    Understanding the early steps governing the differentiation of hESCs will facilitate better control over differentiation for regenerative medicine and drug discovery applications. ...

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