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Search Results - Drug Design
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  • Multitasking Multiplex Assays
    ... Gene-disease associations have the potential to revolutionize drug production [and to] ... Cimler. "Looking ahead, it is likely we will see more use of adaptive trial design. For ...
    10-15-2013
  • Deciphering RNA Secondary Structure
    ... He has since used phi29 packaging RNA (pRNA) for siRNA or drug delivery to specific cells ... Although a number of techniques are available to design RNA nanoparticles, Dr. Guo's group ...
    10-15-2013
  • Growing and Preparing Adult Stem Cells
    Closed hoods with integrated incubation chambers are a key design feature in the Xvivio ... that with multiple rounds of treatment the drug is toxic to the hematopoietic stem cell ...
    10-15-2013
  • 3 Win Nobel Chemistry Prize for Computer Modeling Used in Drug...
    physics has entailed simulations of how a drug binds with its target protein in the ... And then, you could use it to design drugs, or in my case, to satisfy your curiosity," ...
    10-9-2013
  • NIMH Awards Optivia $1.8M toward CNS Drug Development
    nervous system (CNS) physiology and create novel tools to help design new CNS drugs, identify new drug targets, expand drug indications, and manage potential drug side effects. ...
    10-2-2013
  • CROs: Is Yours Meeting Your Needs?
    industry and make up a large portion of the R&D budgets of many large drug manufacturers. ... look to us for guidance on experimental design or for advice on data quality control and ...
    10-1-2013
  • Advertorial: AbbVie Contract Manufacturing
    ... design technology for chemical and microbiological testing, and AbbVie is approved for the highest industry classifications of potency requiring no open handling. Drug ...
    10-1-2013
  • Advertorial: Florida Biologix
    model within the preclinical and Phase I/II stages of the drug development cycle. ... Florida Biologix can provide a services package starting from process design and ...
    10-1-2013
  • Advertorial: Promega
    genomics, proteomics, cellular analysis, drug discovery, and genetic identity, ... will come to your laboratory or design online training specifically for your requirements. ...
    10-1-2013
  • Advertorial: United States Pharmacopeial Convention
    ... In addition to monographs for drug substances, drug products, and excipients, USP-NF ... Some specific USP-NF general chapter topics for biologics cover the design, validation, ...
    10-1-2013
  • Amgen Plans R&D Center in China
    The SIAIS says it has It has seven key laboratories in the fields of antibody design, structural biochemistry, antibody-drug conjugate (ADC) chemistry, antibody therapeutics, ...
    9-25-2013
  • Literature Review: Probing Protein Oligomerization
    An emerging cancer drug target, pro-oncogenic protein anterior gradient-2 (AGR2), was ... emission as the readout, the assay design was based on the MAB recognition of ...
    9-25-2013
  • AstraZeneca Licenses 3 X-Chem Drug Discovery Programs
    X-Chem said the licensing deal was based on the success of its small molecule drug ... Our discovery platform capitalizes on multiple proprietary innovations in library design, ...
    9-24-2013
  • Fine-Tuning Formulation Processes
    The final material we use should be representative of the drug substance produced during ... CMC has employed high-throughput and design-of-experiment approaches to obtain the most ...
    9-15-2013
  • Designing and Managing Modern Biobanks
    Precision Medicine Biobanking is rapidly becoming an integral aspect of drug development ... concentrations may help us design interventions to restore the patient to normal levels. ...
    9-15-2013
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    Journal Articles

  • Design of Experiments to Optimize an In Vitro Cast to Predict...
    Samir Shah, Colin J Dickens, David J Ward, Anna A Banaszek, Chris George, Wallter Horodnik
    Journal of Aerosol Medicine and Pulmonary Drug Delivery
    Design of Experiments to Optimize an In Vitro Cast to Predict Human Nasal Drug Deposition Journal of Aerosol Medicine and Pulmonary Drug Delivery BACKGROUND: Previous studies ...
  • Coactivators in Assay Design for Nuclear Hormone Receptor Drug...
    Taosheng Chen, Wen Xie, Michele Agler, Martyn Banks
    ASSAY and Drug Development Technologies
    Coactivators in Assay Design for Nuclear Hormone Receptor Drug Discovery ASSAY and Drug Development Technologies Nuclear hormone receptors (NHRs) represent one of the most ...
  • The Current Status of Drug Discovery Against the Human Kinome
    Richard M. Eglen, Terry Reisine
    ASSAY and Drug Development Technologies
    Most "classical" drug discovery efforts employ rational drug design methods based upon structural information to identify compounds targeting the enzyme catalytic domain. Novel ...
  • Positional Adaptability in the Design of Mutation-Resistant Nonnucleos...
    Aldo Bruccoleri
    AIDS Research and Human Retroviruses
    It is proposed here that the usual 'lock and key' model, with respect to NNRTI drug design, be expanded to consider creating 'master keys' that would automatically adjust ...

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