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Search Results - Drug Design
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  • Adding Diversity to Clinical Trial Investigators and Participants
    ... make sense that when you're testing the drug, you test it in a heterogeneous group," Dr. ... principles of effective clinical trial design, provide them with tools for conducting ...
    8-9-2013
  • Novartis, Ensemble Therapeutics Launch Collaborations
    new small molecule treatments against undisclosed Novartis-specified drug targets. ... with its receptor has complicated the design of traditional small molecule ...
    8-6-2013
  • Molecular Imaging Driving Development
    making, improved clinical trial design, and more confident lead candidate selection. Imaging technologies are also being used for drug safety assessment, both to screen ...
    8-1-2013
  • Improving Preclinical Research
    journals, and regulators as how best to design, implement, and evaluate preclinical research. Triple Threat That so few drug candidates progress to-and many fail ...
    7-29-2013
  • Six Websites You Need to Bookmark: August Picks
    ... There is a brief discussion on applications of peptides and peptides in drug discovery, as ... MouseMine ★★★★ www.mousemine.org/mousemine/begin.do + Good site design, advanced ...
    7-22-2013
  • Ipsen to Acquire Syntaxin for $206M+
    Ipsen said today it will buy drug developer Syntaxin in a deal that could reach more than ... The companies said the deal will enable Ipsen to use Syntaxin's know-how in the design, ...
    7-15-2013
  • Biogen Idec, Sobi Cite Promising Phase III Results for Hemophilia...
    ... the body, clinicians could design individual dosing regimens to reduce bleed frequency, Baxter said in a statement. Companies say their hemophilia drug candidate Eloctate can ...
    7-5-2013
  • HTRF Applications in New Drug Discovery
    ... libraries for potential new drug candidates to be used in an HTRF high-throughput screen. ... He added that the power of the approach comes from the design of the screen. "In one ...
    7-1-2013
  • Microbioreactor Analysis Module
    For over 20 years, TAP has been the leader in the design and development of automated cell culture systems with applications in bioprocessing, drug discovery and regenerative ...
    7-1-2013
  • Downstream Process Bottlenecks
    and downstream operations. "Legacy plant design issues are what led to the discussion of ... to what is by far the "slow step" in drug development, as well as to its ...
    7-1-2013
  • Blood-Based Tumor Sequence
    ... sample for the presence of cells containing a mutation for which a drug is available. ... Thus the design, identification, and longitudinal analysis of patient cohorts can be ...
    7-1-2013
  • Targeting Deranged Metabolism to Treat Cancer
    ... likely to respond to Agios' IDH1 and IDH2 drug candidates, and to develop and potentially ... understanding of cancer metabolism to design first-in-class cancer medicines for ...
    7-1-2013
  • Assay Development Driving Personalized Medicine
    ... is unfamiliarity with the language of design of clinical utility and a lot of hard ... diagnostics can be used to identify populations that will respond to a particular drug. ...
    7-1-2013
  • Reducing the Cost of Peptide Synthesis
    CPPs can form chemical linkages with their drug cargo, or they may form stable, ... Infrared heating can also be incorporated into the design of the Symphony X. It has been ...
    7-1-2013
  • Roche, AstraZeneca to Share Some Drug Design Data
    Roche and AstraZeneca said today they will share early research data related to drug design with each other and outside organizations, with the goal of speeding up discovery of ...
    6-26-2013
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    Journal Articles

  • Glucocorticoid Receptor Ligands Modulate Cardiovirus encephalomyocardi...
    Marie-Cecile Didiot, Claudia Agarinis, Thibault Varin, Hua Wu, Thomas Nelson, Douglas W. Selinger, Frederick King, Ansgar Schuffenhauer, Christian N. Parker
    ASSAY and Drug Development Technologies
    ASSAY and Drug Development Technologies The use of small molecules to modulate cellular ... This report described the design of a functional, high throughput screen of small ...
  • Marker Gene Screening for Human Mesenchymal Stem Cells in Early...
    Shien Zou, Shaofen Zhang, Qiqi Long, Yuankui Cao, Wei Zhang
    Genetic Testing and Molecular Biomarkers
    of hMSCs into osteoblast which can be used for bone disease treatment. Moreover, small molecules like W-3 were retrieved and provided directions for future drug design.
  • Physician Allocation of Medicare Resources for Patients with...
    Daniel J. Rocke, Walter T. Lee, Halton W. Beumer, Donald H. Taylor, Kristine Schulz, Steven Thomas, Liana Puscas
    Journal of Palliative Medicine
    Design: OHNS physicians used an online version of a validated tool for assessing ... Care, Cosmetic Care, Dental and Vision, Drug Coverage, Home Improvement, House Calls, ...
  • In Vitro Investigation of the Effect of Ambient Humidity on Regional...
    Farzin M. Shemirani, Susan Hoe, David Lewis, Tanya Church, Reinhard Vehring, Warren. H. Finlay
    Journal of Aerosol Medicine and Pulmonary Drug Delivery
    and Suspension MDIs Journal of Aerosol Medicine and Pulmonary Drug Delivery Background. ... These results have implications during dosage form design and testing, and for patient ...

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