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Search Results - Downstream Processing
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  • Downstream Processing
    Cambridge MA UNITED STATES shortprograms.mit.edu/dsp
    8-5-2013
  • Still a Place for Steel and Glass
    For one of Infors' niche markets, biofuels, single-use equipment is mostly limited to downstream processing and what Abellan calls "peripheral equipment such as harvest bags or ...
    8-1-2013
  • Downstream Process Bottlenecks
    reduced efficiency, and higher process-related costs. "When we speak with downstream processing groups, they still mention the classic bottlenecks of chromatography, buffer ...
    7-1-2013
  • Improving Molecular Distribution Analysis
    with the downstream mass spectrometric analytical instrumentation. Lack of usable inhibitors in combination with thin tissue sections that thaw during processing leads to ...
    7-1-2013
  • Reducing the Cost of Peptide Synthesis
    ... Endotoxins are removed during HPLC purification, explains John McKinley of American Peptide, and subsequent downstream processing must be performed under controlled, clean room ...
    7-1-2013
  • The 11 Golden Rules of Working with Proteomic Samples
    Avoid group-wise processing as it may introduce a bias in the results. Understand the ... wanting to extract as much as possible while not interfering with downstream analysis. ...
    6-21-2013
  • Next-Generation Flow Sorting
    These limitations, plus the high unit and sample processing costs, must be overcome to ... then be retrieved from the cartridge and used for any number of downstream applications. ...
    6-15-2013
  • ReGen Med: Straight Out of Mythology
    ... but inducing a distinct cell fate, by biasing signaling to specific downstream pathways. ... To the Clinic According to Aastrom Biosciences, its cell-processing system selectively ...
    6-11-2013
  • Strategies to Optimize Cell Culture
    ... Downstream processing is where people can see problems." Dr. Chalmers' group has developed a device to help companies test clones to determine how sensitive they may be to specific ...
    6-1-2013
  • Flexibility in Biopharmaceutical Manufacturing Capacity
    ... Technologies enabling higher bioreactor titers have created downstream processing (DSP) bottlenecks and limitations on equipment throughput. And the inevitable development and ...
    5-28-2013
  • Improving Proteomics Approaches
    Gravity entails very long sample prep times and is unsuitable for parallel processing. ... Subsequently, the noncovalent interactions have emerged as central in events downstream ...
    5-15-2013
  • Productivity Boost for Biopurification
    Twin-Column Ultra-High Resolution Chromatography Chromatography is the most important unit operation in the downstream processing of biopharmaceuticals. In most cases, at least two ...
    5-15-2013
  • Separation of Therapeutic Biomolecules
    of proteins was the focus of a series of talks at Tosoh Bioscience's recent "HIC/RPC Bioseparation Conference: Advancements, Applications and Theory in Downstream Processing." ...
    5-1-2013
  • Boosting Downstream Productivity
    The development of biopharmaceuticals, from initial lab work through production and final regulatory approval, is a complex process. Downstream processing steps can represent up to ...
    4-15-2013
  • Single-Use Bioreactor Roundup
    ... leachables are a minimum, but it can also be necessary to demonstrate that they are treated in the appropriate manner during the downstream processing step to limit any risks. Mr. ...
    4-15-2013
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    Journal Articles

  • Electrochemically Induced Crystallization as a Sustainable Method...
    Tahmineh Nasrollahnejad, Johan Urbanus, Joop H. ter Horst, Dirk Verdoes, Cornelis P.M. Roelands
    Industrial Biotechnology
    so-called base case produces a solid waste, while the second employs electrodialysis at the end of downstream processing to regenerate the waste salt and re-use the base and acid. ...
  • Was cDNA Sequences Modulate Transgene Expression of Was Promoter...
    Miguel G. Toscano, Karim Benabdellah, Pilar Muñoz, Cecilia Frecha, Marién Cobo, Francisco Martín
    Human Gene Therapy and Part B: Methods
    Insertion of Was cDNA sequences downstream of eGFP in these LVs had a negative effect on ... have demonstrated that the mechanism involves Was promoter regulation and RNA processing. ...
  • Reproducible High Yields of Recombinant Adeno-Associated Virus...
    Sylvain Cecchini, Tamas Virag, Robert M. Kotin
    Human Gene Therapy and Part B: Methods
    Using a variety of processing media, we developed a reliable and routine downstream procedure for rAAV production that is scalable from 0.02- to 200-liter cultures. To facilitate ...
  • Development and Evaluation of a Real-Time Fluorescent Polymerase...
    Gabriel Rensen, Wayne Smith, Juliana Ruzante, Mary Sawyer, Bennie Osburn, James Cullor
    Foodborne Pathogens and Disease
    We have developed a presample processing technique for extracting DNA from cattle feed ... PCR inhibitors and eluting the DNA from the FTA® card for downstream PCR analysis. ...

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