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Search Results - Downstream Processing
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  • Scaleup Issues for Single Use and Steel
    the recent Sartorius Stedim Biotech "European Upstream and Downstream Technology Forum." ... Anne Gilbert, Ph.D., deputy director for upstream processing at Novasep. According to Dr. ...
    10-15-2013
  • Refining Sample Prep for Molecular Dx
    facilitate the downstream detection of target nucleic acids, proteins, and other analytes. ... field detection of microbial infection, again requiring initial sample-processing steps. ...
    10-1-2013
  • Tips for Working Optimally with CMOs
    ... may have an issue with expression levels, or have no system at all," Hetrick explains. "Or the protein may have inherent problems related to upstream or downstream processing." ...
    10-1-2013
  • Advertorial: Corning Life Sciences
    numerous advantages over the use of serum, including lot-to-lot consistency, the elimination of exogenous agents, simpler downstream processing, and fewer regulatory obstacles. ...
    10-1-2013
  • Fine-Tuning Formulation Processes
    Such "preformulation" studies also help identify suitable analytical methods, and even guide downstream processing. CMC has employed high-throughput and design-of-experiment ...
    9-15-2013
  • Designing and Managing Modern Biobanks
    ... processing and storage procedures that they believe are 'the best,' there need to be ways to validate these claims and unify sample quality standards through downstream ...
    9-15-2013
  • Still a Place for Steel and Glass
    For one of Infors' niche markets, biofuels, single-use equipment is mostly limited to downstream processing and what Abellan calls "peripheral equipment such as harvest bags or ...
    8-1-2013
  • Downstream Process Bottlenecks
    reduced efficiency, and higher process-related costs. "When we speak with downstream processing groups, they still mention the classic bottlenecks of chromatography, buffer ...
    7-1-2013
  • Improving Molecular Distribution Analysis
    with the downstream mass spectrometric analytical instrumentation. Lack of usable inhibitors in combination with thin tissue sections that thaw during processing leads to ...
    7-1-2013
  • Reducing the Cost of Peptide Synthesis
    ... Endotoxins are removed during HPLC purification, explains John McKinley of American Peptide, and subsequent downstream processing must be performed under controlled, clean room ...
    7-1-2013
  • The 11 Golden Rules of Working with Proteomic Samples
    Avoid group-wise processing as it may introduce a bias in the results. Understand the ... wanting to extract as much as possible while not interfering with downstream analysis. ...
    6-21-2013
  • Next-Generation Flow Sorting
    These limitations, plus the high unit and sample processing costs, must be overcome to ... then be retrieved from the cartridge and used for any number of downstream applications. ...
    6-15-2013
  • ReGen Med: Straight Out of Mythology
    ... but inducing a distinct cell fate, by biasing signaling to specific downstream pathways. ... To the Clinic According to Aastrom Biosciences, its cell-processing system selectively ...
    6-11-2013
  • Strategies to Optimize Cell Culture
    ... Downstream processing is where people can see problems." Dr. Chalmers' group has developed a device to help companies test clones to determine how sensitive they may be to specific ...
    6-1-2013
  • Flexibility in Biopharmaceutical Manufacturing Capacity
    ... Technologies enabling higher bioreactor titers have created downstream processing (DSP) bottlenecks and limitations on equipment throughput. And the inevitable development and ...
    5-28-2013
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    Journal Articles

  • Electrochemically Induced Crystallization as a Sustainable Method...
    Tahmineh Nasrollahnejad, Johan Urbanus, Joop H. ter Horst, Dirk Verdoes, Cornelis P.M. Roelands
    Industrial Biotechnology
    so-called base case produces a solid waste, while the second employs electrodialysis at the end of downstream processing to regenerate the waste salt and re-use the base and acid. ...
  • Reproducible High Yields of Recombinant Adeno-Associated Virus...
    Sylvain Cecchini, Tamas Virag, Robert M. Kotin
    Human Gene Therapy and Part B: Methods
    Using a variety of processing media, we developed a reliable and routine downstream procedure for rAAV production that is scalable from 0.02- to 200-liter cultures. To facilitate ...
  • An Integrated Multiassay Approach to the Discovery of Small-Molecule...
    Michael F.A. Finley, Mary Lou Lubin, Michael P. Neeper, Edward Beck, Yi Liu, Christopher M. Flores, Ning Qin
    ASSAY and Drug Development Technologies
    role in nociceptive processing. For example, Cav2.2 is localized at presynaptic terminals of pain fibers in the dorsal horn, and it serves as a downstream effector of µ-opioid ...
  • Validation of Free Flow Electrophoresis as a Novel Plasma and...
    Gwenaelle Gaillard, Jean-Pierre Trezzi, Fotini Betsou, Fay Betsou
    Biopreservation and Biobanking
    Validation of Free Flow Electrophoresis as a Novel Plasma and Serum Processing and ... efficiently and reproducibly and to facilitate downstream proteomic applications. ...

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