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Search Results - Dopamine
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  • Diverse Neurological Disorders Appear to Share Tangled Metabolic...
    The best recognized neural consequences of HPRT deficiency are defective basal ganglia expression of the neurotransmitter dopamine and aberrant dopamine neuronal function. Hoping ...
    10-10-2013
  • Not-So-Total Recall: Selectively Erasing Unwanted Memories
    ... the role of dopamine, a neurotransmitter involved in reward and pleasure centers in the brain and known to modify dendritic spines. Previous studies had shown dopamine is released ...
    9-10-2013
  • Multiparametric Assays for Cardiomyocytes
    ... However, cell covered area was 71% compared to 82% in DMSO-treated controls-not a significant reduction in cell viability. The dopamine inverse agonist haloperidol had a distinct ...
    9-1-2013
  • Novel Parkinson's Target Uncovered
    The brain cells that make dopamine were dying. Since AIMP2 is known for its role in the process of making new proteins, the researchers thought the cell death was caused by ...
    8-26-2013
  • Treatment Options for Side Effects: Today and Tomorrow
    ... triggered by these agents. Specifically, dopamine antagonists, such as promethazine ... to treat these "off" episodes is the dopamine agonist apomorphine, (Apokyn® in the ...
    8-20-2013
  • Drug Candidates on Trial
    ... According to the company, SD-809 inhibits vesicular monoamine transporter type 2, decreasing the amount of dopamine available to work at nerve terminals, and thereby reducing ...
    7-22-2013
  • Improving Molecular Distribution Analysis
    ... Goodwin has also studied the distribution of raclopride (an antagonist binder to the D2 dopamine receptor with a body half-life of 30 minutes) in mouse brain tissue. Results show ...
    7-1-2013
  • Merck Sells COMT Inhibitor Rights to Cerecor
    2013. COMT is an enzyme that breaks down dopamine, a neurotransmitter that plays a key ... increasing dopamine levels in areas of the brain affected by these conditions. ...
    3-20-2013
  • AZ Licensing Vanderbilt Neuroscience Compounds
    Selective activation of M4, through positive allosteric modulation, has been shown in animal models to block dopamine release in several key brain regions, and improve cognitive ...
    1-14-2013
  • Gene Variant Might Lead to a Longer Life
    This derivative of a dopamine-receptor gene-called the DRD4 7R allele-appears in ... The variant gene is part of the dopamine system, which facilitates the ...
    1-4-2013
  • What Dieting Does to Your Brain
    For example, CREB is a molecule that controls the activation of genes involved in brain function, including those that cause the production of dopamine. It contributes to memory ...
    12-12-2012
  • Advertorial: Quantifying Fluorescent Ligand Binding to GPCRs...
    ligands from CellAura for adenosine ( Figure 1A ) and dopamine (not shown) receptors. ... Ligand CA200645 is an adenosine A3 selective ligand, while CA200767 is a dopamine D1 ...
    12-1-2012
  • Placebo Effect Linked to Dopamine-Clearing Enzyme
    of an enzyme responsible for clearing dopamine from the prefrontal cortex region of the ... than the native enzyme at mopping up dopamine that has been released from nerve synapses. ...
    10-24-2012
  • Parkinson's Gene Mutation Damages Neuronal Nuclei
    ... with loss of neurons that produce dopamine and subsequent motor impairment, could ... cell transplantation to compensate for dopamine deficits," he notes. "Our work provides ...
    10-22-2012
  • Two Nobelists Honored for Protein Receptor Discoveries
    Others alert cells to the presence of adrenalin, histamine, dopamine and serotonin. "This ground-breaking work spanning genetics and biochemistry has laid the basis for much of our ...
    10-10-2012
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    Journal Articles

  • Dopamine Receptors in Human Embryonic Stem Cell Neurodifferentiation
    Glenn S. Belinsky, Carissa L. Sirois, Matthew T. Rich, Shaina M. Short, Anna R. Moore, Sarah E. Gilbert, Srdjan D. Antic
    Stem Cells and Development
    Dopamine Receptors in Human Embryonic Stem Cell Neurodifferentiation Stem Cells and ... The expression of 5 dopamine receptor subtypes (mRNA and protein) was analyzed at each ...
  • Dopamine-Related Genotypes and the Dose-Response Effect of Methylpheni...
    John J. Leddy, James G. Waxmonsky, Robert J. Salis, Rocco A. Paluch, Elizabeth M. Gnagy, Patrick Mahaney, Richard Erbe, William E. Pelham, Leonard H. Epstein
    Journal of Child and Adolescent Psychopharmacology
    Dopamine-Related Genotypes and the Dose-Response Effect of Methylphenidate on Eating in ... the effects of methylphenidate (MPH), a dopamine (DA) transport inhibitor, on appetite in ...
  • Dopamine Fails to Regulate Activation of Peripheral Blood Lymphocytes...
    Maurizio Giorelli, Paolo Livrea, Maria Trojano
    Journal of Interferon & Cytokine Research
    Dopamine Fails to Regulate Activation of Peripheral Blood Lymphocytes from Multiple ... Journal of Interferon & Cytokine Research The neurotransmitter dopamine counteracts T cell ...
  • Dopamine Receptor 4 (DRD4) 7-Repeat Allele Predicts Methylphenidate...
    Stephanie Hamarman, John Fossella, Celal Ulger, Michael Brimacombe, James Dermody
    Journal of Child and Adolescent Psychopharmacology
    Dopamine Receptor 4 (DRD4) 7-Repeat Allele Predicts Methylphenidate Dose Response in ... Objective: Genetic polymorphisms of the dopamine neurotransmitter system have been ...

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