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  • Improving Proteomics Approaches
    ... A PARP inhibitor, therefore, could sustain DNA damage in susceptible cells, causing tumor ... subsequently selecting synthetic recombinant antibodies using phage-display technology. ...
    5-15-2013
  • Moving Genomics Closer to the Clinic
    ... Study of Drug Development told MIT's Technology Review , reimbursement remains "one of ... number of medications targeted to people's DNA grows. "Once you get 10 drugs that require ...
    5-15-2013
  • Mass Spec Provides Peek into PTMs
    Also known as "next-generation proteomics," this approach has been developed to complement the existing next-generation DNA sequencing technology. The application of mass spec to ...
    5-15-2013
  • Highlights from AACR
    ... ACD and Definiens recently initiated an early access program for the RNAscope SpotStudio(tm) technology for quantitative in situ RNA biomarker analysis. EZ DNA ...
    5-15-2013
  • Making Vaccines from Parts
    synthetic DNA into genes and then corrected errors in the resulting gene sequences. ... Using this synthetic technology, a lab near the site of an outbreak could obtain genetic ...
    5-14-2013
  • A First: hESCs Generated from Somatic Cells
    caused by mutations in mitochondrial DNA, somatic cell nuclear transfer allows ... said. "Since we have opened up the technology, hopefully the technique can be perfected. ...
    5-14-2013
  • Companion Diagnostics: 52 Pick-Up
    Some announcements did not cite the specific technology being applied in the trumpeted ... Fluorescence in situ hybridization (FISH) DNA probe assay determines the qualitative ...
    5-9-2013
  • Cancer Diagnostics, Pushing the Boundaries
    Researchers and clinicians alike are relying on sequencing technology and genomic, ... (yellow; 3-5 dots), negative (blue; DNA and Protein Biomarker Analysis ...
    5-8-2013
  • Foundation Medicine Taps Sloan-Kettering Clinical, Genomics Expertise...
    The resulting test will be based on technology, methods, and computational algorithms ... This new product, however, uses both DNA and RNA sequencing to identify genomic ...
    5-2-2013
  • Biomarkers Take Center Stage
    ... The technology increases the observable signal noise ratio from a few hundred to over ... protein and miRNA expression, and DNA methylation, coming up with a list of ...
    5-1-2013
  • Metabolomics Advances Reshape Dx Arena
    ... of DNA synthesis. The data showed clear response in metabolic pathways related to nucleotide biosynthesis, but not in other pathways. "We plan to perfect this technology to ...
    5-1-2013
  • Separation of Therapeutic Biomolecules
    This technology is increasingly being applied to other challenging nonantibody therapeutic ... protein and double-stranded DNA removal, and were suitable for use in production scaleup. ...
    5-1-2013
  • Comparative Genomics: Insights into Disease Susceptibility
    ... Sequencing Technologies Hold the Key Different DNA sequencing technologies are used to ... as text files or BAM files. The technology can typically map a human genome ...
    5-1-2013
  • Detecting Acquired Drug Resistance in Cancer
    ... Originally developed in the laboratory of Bert Vogelstein, M.D., at Johns Hopkins, BEAMing technology involves conversion of single DNA molecules to single magnetic beads, each ...
    4-29-2013
  • Agilent Takes $21M Stake in Gen9
    Its oligo synthesis technology produces what the company says is the highest-quality long DNA compared to that of any commercially available source. Also, Agilent in recent years ...
    4-24-2013
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    Journal Articles

  • Nontoxic Genetic Engineering of Mesenchymal Stem Cells Using...
    Devang K. Thakor, Yang D. Teng, Hideaki Obata, Kentaro Nagane, Shigeru Saito, Yasuhiko Tabata
    Tissue Engineering, Part C: Methods
    the biological inertness of pullulan-spermine/DNA anioplexes. Collectively, these data introduce a straightforward technology for genetic engineering of adult stem/progenitor ...
  • DNA Microarrays in Dermatology and Skin Biology
    Miroslav Blumenberg
    OMICS: A Journal of Integrative Biology
    All these exciting facets of skin have been explored using DNA microarrays. Researchers in skin biology and dermatology were among the first to implement this technology and we ...
  • Nucleofection, an Efficient Nonviral Method to Transfer Genes...
    Gregor Von Levetzow, Jan Spanholtz, Julia Beckmann, Johannes Fischer, Gesine Kögler, Peter Wernet, Michael Punzel, Bernd Giebel
    Stem Cells and Development
    In our study, we have optimized the nucleofection technology, a modified electroporation strategy, to introduce plasmid DNA into freshly isolated human HSC-enriched CD34+ cells. ...
  • Unraveling the Mysteries of Aging Through a Hutchinson-Gilford...
    Ryan N. Serio
    Rejuvenation Research
    A high degree of genomic instability occurs as DNA double-strand breaks are introduced but ... have been exposed using antisense technology, and identification of novel molecular ...

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