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Search Results - DNA Methylation
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  • Improving Proteomics Approaches
    ... modifications such as phosphorylation and methylation. Subsequently, the noncovalent interactions have emerged as central in events downstream from DNA damage, such as cancer. ...
    5-15-2013
  • Highlights from AACR
    ... ACD and Definiens recently initiated an early access program for the RNAscope SpotStudio(tm) technology for quantitative in situ RNA biomarker analysis. EZ DNA Methylation(tm)-Ligh...
    5-15-2013
  • Companion Diagnostics: 52 Pick-Up
    ... will be used to determine the methylation status of the MGMT promotor gene in ... research program by identifying specific DNA sequences to guide physicians in ...
    5-9-2013
  • Cancer Diagnostics, Pushing the Boundaries
    ... genomic deletions, or promoter methylation, in which the PTEN gene may be present and unadulterated but epigenetic changes to the regulatory DNA upstream of the gene block ...
    5-8-2013
  • Exposing the Exposome
    Of these, DNA methylation is at the most advanced stage of understanding. "With methods that can comprehensively measure the DNA methylation status, for example, it has now become ...
    5-1-2013
  • Biomarkers Take Center Stage
    ... Studies published in the past year have looked at somatic mutations, gene copy number aberrations, gene expression abnormalities, protein and miRNA expression, and DNA methylation, ...
    5-1-2013
  • Twin Study Elucidates Epigenetics' Role in Autism
    The researchers add that epigenetic changes are potentially reversible and may therefore provide targets for the development of new therapies. The team studied DNA methylation, ...
    4-23-2013
  • Pathway Analysis to Decipher Data
    ... event, such as anaphase, metaphase, and DNA replication, and thus the user is provided ... the left represent tabular data from methylation and mRNA expression analyses, the ...
    4-15-2013
  • Querying the Cancer Transcriptome
    ... Park. After correlating the insertion sites with DNA methylation and gene expression data, Dr. Park and colleagues found that genes affected by insertions were, on average, ...
    4-1-2013
  • Epigenetics Opens New Avenues for DNA Research
    ... by studies showing increasingly divergent DNA methylation, histone acetylation, and gene expression patterns between monozygotic twin pairs as they are advancing with age. ...
    4-1-2013
  • Flipping the Genetic Switch
    However, the added information provided by methylation allows scientists to determine where specific DNA came from. "Methylation patterns are like fingerprints, showing which ...
    3-28-2013
  • PrimeraDx on Quest for New Companion Dx
    system in August 2011 and says the system can simultaneously detect and quantify disparate target types, such as mRNA, miRNA, SNPs, DNA mutations, fusions, and DNA methylation. ...
    3-26-2013
  • Gene Expression Analysis Making Inroads
    professor at University of Wisconsin-Madison, to ask how differences in maternal diet during pregnancy induce gene expression and DNA methylation changes in fetal tissues in sheep. ...
    3-15-2013
  • Genome Editing for R&D and Therapeutics
    ... enhancing efficiency of the technology. "Although TALENs have exquisite programming specificity, one problem is their sensitivity to methylation, a ubiquitous DNA modification. ...
    3-1-2013
  • Nucleic Acid Sample Preparation in MDx
    ... This is critical for downstream applications such as next-generation sequencing. This novel method relies on the differential methylation patterns of nuclear DNA as compared to ...
    3-1-2013
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    Journal Articles

  • No Link Between X Chromosome Inactivation Pattern and Simple...
    Thomas Heiberg Brix, Pia Skov Hansen, Gun Peggy S. Knudsen, Marianne K. Kringen, Kirsten Ohm Kyvik, Karen Helene Ørstavik, Laszlo Hegedüs
    Thyroid
    XCI analysis was performed by predigestion of DNA using the methylation-sensitive enzyme Hpall, followed by polymerase chain reaction of the polymorphic CAG repeat of the androgen ...
  • Comparison of Gene-Specific DNA Methylation Patterns in Equine...
    Catherine H. Hackett, Line Greve, Kira D. Novakofski, Lisa A. Fortier
    Stem Cells and Development
    Comparison of Gene-Specific DNA Methylation Patterns in Equine Induced Pluripotent Stem Cell Lines with Cells Derived From Equine Adult and Fetal Tissues Stem Cells and Development ...
  • The Epigenetic Regulation of Stem Cell Factors in Hepatic Stellate...
    Sven Reister, Claus Kordes, Iris Sawitza, Dieter Häussinger
    Stem Cells and Development
    The Epigenetic Regulation of Stem Cell Factors in Hepatic Stellate Cells Stem Cells and Development The epigenetic regulation by DNA methylation is an important mechanism to ...
  • Regulation of Stem Cell Pluripotency and Differentiation Involves...
    Vasundhra Kashyap, Naira C. Rezende, Kymora B. Scotland, Sebastian M. Shaffer, Jenny Liao Persson, Lorraine J. Gudas, Nigel P. Mongan
    Stem Cells and Development
    We will discuss how distinct epigenetic repressive pathways involving polycomb complexes, DNA methylation, and microRNAs cooperate to reduce transcriptional noise and to prevent ...

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