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Search Results - DNA Methylation
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  • Target Enrichment for Clinical and Molecular Diagnostics
    ... The method needed to be good enough to enable an accurate microbiome analysis. "What we came up with was an idea to separate those two types of DNA based on methylation pattern. ...
    10-15-2013
  • Epigenetic Markers Found for Head and Neck Cancers
    The expression of these genes was inversely correlated with particular DNA methylation marks, suggesting the genes are epigenetically modified in these cancers." Dr. Tuck-Teh said ...
    10-2-2013
  • Making Cancerous Mr. Hyde Behave Like a Good Dr. Jekyll
    in the journal article ("Arginine methylation-dependent reader-writer interplay ... This helps prevent the buildup of DNA errors and the development of cancer. The research ...
    9-27-2013
  • Explication of Lifestyle-Metabotype Links Deemed Feasible
    After conducting an epigenome-wide association study between DNA methylation and metabolic traits, scientists conclude that DNA methylation plays an important role in regulating ...
    9-23-2013
  • Otsuka Acquires Astex for $866M
    Four of these are in Phase II clinical trials, including SGI-110, a DNA methylation inhibitor, and AT13387, an inhibitor of heat shock protein 90 (HSP90). Both SGI-110 and AT13387 ...
    9-5-2013
  • Manipulating Methodologies for Reprogramming Cells
    ... Taking this approach, known as comprehensive high-throughput array-based relative methylation, the researchers revealed that most tissue-specific DNA methylation differences, which ...
    9-1-2013
  • Unraveling the Transcriptome
    Investigators in Dr. He's group were the first to reveal that, just like DNA and histone methylation, RNA methylation is reversible. They found that fat mass and obesity-associated ...
    7-1-2013
  • Targeting Deranged Metabolism to Treat Cancer
    ... Blockade of the mutant enzyme also impaired the growth of IDH1-mutant-but not IDH1-wild-type-glioma cells without changes in genome-wide DNA methylation. This data, the authors ...
    7-1-2013
  • Biomarker Study Suggests Potential Alternative to Colonoscopy
    Oh explained. "We are currently preparing another set of clinical validation studies evaluating SDC2 methylation in serum DNA from patients with early adenoma." "Genome-wide ...
    6-7-2013
  • Diet, Exercise...Epigenetics?
    but also to his or her particular genetic and epigenetic profile." "Differential DNA methylation patterns between high and low responders to a weight loss intervention in ...
    5-30-2013
  • Targeting Deranged Metabolism to Treat Cancer
    ... Blockade of the mutant enzyme also impaired the growth of IDH1-mutant-but not IDH1-wild-type-glioma cells without changes in genome-wide DNA methylation. This data, the authors ...
    5-30-2013
  • Epigenetic Changes Predict Postpartum Depression
    Writing today in Molecular Psychiatry, Hopkins' Zachary Kaminsky, Ph.D., and his colleagues show that DNA methylation at TTC9B and HP1BP3 correlate significantly with the ...
    5-20-2013
  • Improving Proteomics Approaches
    ... modifications such as phosphorylation and methylation. Subsequently, the noncovalent interactions have emerged as central in events downstream from DNA damage, such as cancer. ...
    5-15-2013
  • Highlights from AACR
    ... ACD and Definiens recently initiated an early access program for the RNAscope SpotStudio(tm) technology for quantitative in situ RNA biomarker analysis. EZ DNA Methylation(tm)-Ligh...
    5-15-2013
  • Companion Diagnostics: 52 Pick-Up
    ... will be used to determine the methylation status of the MGMT promotor gene in ... research program by identifying specific DNA sequences to guide physicians in ...
    5-9-2013
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    Journal Articles

  • DNA Methylation Changes Correlate with Gleason Score and Tumor...
    Lissette Delgado-Cruzata, Gregory W. Hruby, Karina Gonzalez, James McKiernan, Mitchel C. Benson, Regina M. Santella, Jing Shen
    DNA and Cell Biology
    DNA Methylation Changes Correlate with Gleason Score and Tumor Stage in Prostate Cancer DNA and Cell Biology DNA methylation, a widely used epigenetic mark, has been associated ...
  • DNA Methylation in Peripheral Blood Cells of Pigs Cloned by Somatic...
    Fei Gao, Shengting Li, Lin Lin, Jian Li, Yonglun Luo, Xiuqing Zhang, Anders Lade Nielsen, Lars Bolund
    Cellular Reprogramming
    DNA Methylation in Peripheral Blood Cells of Pigs Cloned by Somatic Cell Nuclear Transfer Cellular Reprogramming Abstract To date, the genome-wide DNA methylation status of cloned ...
  • Differential DNA Methylation Alterations in Radiation-Sensitive...
    M. Ahmad Chaudhry, Romaica A. Omaruddin
    DNA and Cell Biology
    Differential DNA Methylation Alterations in Radiation-Sensitive and -Resistant Cells DNA and Cell Biology An understanding of cellular processes that determine the response to ...
  • Differential DNA Methylation Alterations in Radiation-Sensitive...
    M. Ahmad Chaudhry, Romaica A. Omaruddin
    DNA and Cell Biology
    Differential DNA Methylation Alterations in Radiation-Sensitive and -Resistant Cells DNA and Cell Biology An understanding of cellular processes that determine the response to ...

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