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  • Target Enrichment for Clinical and Molecular Diagnostics
    The isothermal amplification, an effective and simple non-PCR DNA enrichment technique, ... in conjunction with a strand-displacing DNA polymerase to increase the target ...
    10-15-2013
  • Multitasking Multiplex Assays
    ... Software delivers pneumatic signals to the cartridge to move fluids throughout the device and perform all processing steps including cell lysis, DNA or RNA extraction and ...
    10-15-2013
  • Deciphering RNA Secondary Structure
    ... Conditions that give near-quantitative, single-stranded DNA ligation are used, and an Illumina adapter sequence is added to the reverse-transcribed DNA. "Unique sequence identifiers, ...
    10-15-2013
  • Growing and Preparing Adult Stem Cells
    ... Adult stem cells may be reprogrammed by inserting four genes into their DNA, a process that yields induced pluripotent stem cells (iPSCs). The process, however, is fraught with ...
    10-15-2013
  • Sample-Prep Automation in NGS
    All of the major technology platforms rely on ligation of DNA fragments during sample ... At each step of enzymatically modifying DNA into genomic DNA (gDNA), the fragment ...
    10-15-2013
  • Diverse Neurological Disorders Appear to Share Tangled Metabolic...
    In addition, the study shows how HPRT deficiency dysregulates many cellular functions. Disturbed processes include cell cycle and proliferation mechanisms, RNA metabolism, DNA ...
    10-10-2013
  • Thwarting Greatwall May Trigger Mitotic Collapse and Suppress...
    Thanks to this mouse model, they were able to see that cells lacking Greatwall are not capable of adequately dividing themselves. By eliminating Greatwall, cellular DNA does not ...
    10-9-2013
  • A Marriage Gene for Better or Worse
    The reason a person is happily or dismally married may reside in their DNA. According to researchers based at the University of California, Berkeley, it matters whether that person ...
    10-8-2013
  • Ovarian Cancer Treatment Options Multiply
    ... The regulator causes certain tumor cells to divide without DNA repair, killing them. Phase I research suggests that MK-1775 will be particularly effective with DNA-damaging ...
    10-8-2013
  • Designer Baby Patent Awarded to 23andMe
    executive director of the Center for Genetics and Society, a longtime advocate of DNA privacy, said in a statement. "We believe the patent office made a serious mistake in ...
    10-4-2013
  • Epigenetic Markers Found for Head and Neck Cancers
    The expression of these genes was inversely correlated with particular DNA methylation ... Tuck-Teh. "An advantage of epigenetic DNA markers is that it may be possible to measure ...
    10-2-2013
  • DNA Extraction Kit
    DNA extraction technology based on classic organic-phase extraction, avoiding the use of silica columns. Because this approach reduces fragmentation, it provides DNA that ...
    10-1-2013
  • Refining Sample Prep for Molecular Dx
    ... Custom sample diagnostics can also be carried out within the cartridge. "RNA or DNA ... The company recently developed a platform for the isolation of protein, RNA, and DNA from ...
    10-1-2013
  • CROs: Is Yours Meeting Your Needs?
    ... Simple Dichotomy Jeremy Minshull, Ph.D., CEO of DNA 2.0, compresses this continuum of ... that the client already possesses, he explains. "DNA 2.0 takes the middle ground. ...
    10-1-2013
  • CNV Strategies Get a Rethink
    chromosomal breaks that shatter the DNA into tiny fragments, was initially used to ... hybrid panels, where X-rays fragment the DNA and the resolution is very high," says Dr. ...
    10-1-2013
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    Journal Articles

  • DNA Vaccines Employing Intracellular Targeting Strategies and...
    Tae Woo Kim, Jin-Hyup Lee, Liangmei He, David A. K. Boyd, Chien-Fu Hung, T.-C. Wu
    Human Gene Therapy and Part B: Methods
    DNA Vaccines Employing Intracellular Targeting Strategies and a Strategy to Prolong ... Antitumor Effects Compared with a DNA Prime-Vaccinia Boost Regimen Human Gene ...
  • Differential DNA Binding of Ku Antigen Determines Its Involvement...
    Caroline Schild-Poulter, Diamanto Matheos, Olivia Novac, Bo Cui, Ward Giffin, Marcia T. Ruiz, Gerald B. Price, Maria Zannis-Hadjopoulos, Robert J.G. Haché
    DNA and Cell Biology
    Differential DNA Binding of Ku Antigen Determines Its Involvement in DNA Replication DNA and Cell Biology Ku antigen (Ku70/Ku80) is a regulatory subunit of DNA-dependent protein ...
  • DNA-Binding Studies of Fluoxetine Antidepressant
    Soheila Kashanian, Sanaz Javanmardi, Arash Chitsazan, Kobra Omidfar, Maliheh Paknejad
    DNA and Cell Biology
    DNA-Binding Studies of Fluoxetine Antidepressant DNA and Cell Biology Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) antidepressant which is wildly prescribed. The ...
  • DNA Before Proteins? Recent Discoveries in Nucleic Acid Catalysis...
    Aaron S. Burton, Niles Lehman
    Astrobiology
    DNA Before Proteins? Recent Discoveries in Nucleic Acid Catalysis Strengthen the Case Astrobiology Abstract An RNA-DNA World could arise from an all-RNA system with the development ...

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