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Search Results - Crohn Disease
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  • What Junk DNA? It's an Operating System
    Noncoding gene sequences control gene expression and influence disease processes. In the ... material in the regulation of gene expression and its potential role in human disease. ...
    8-6-2013
  • Big Need in IBD: Drugs to Slow Progression
    Innovators Are Working to Develop New Treatments for Inflammatory Bowel Disease The two most common forms of irritable bowel disease are ulcerative colitis and Crohn's disease. The ...
    8-1-2013
  • Parsing the Phenome
    and their contributions to disease risk at the personal and population scales. ... cause-and may be predictive of-disease. "Through life, there's a series of ...
    7-16-2013
  • Macrocycles Shake Up Small Molecules
    ... auto-inflammatory and neurodegenerative conditions such as irritable bowel disease, Crohn's disease, rheumatoid arthritis, Parkinson disease, and Alzheimer's," Dr. Hoflack said. ...
    6-15-2013
  • AbbVie Expands Galapagos Collaboration to Include Crohn's Disease
    the companies are about to launch a Phase IIb trial, to include Crohn's disease as well. ... The Phase II study will measure both the drug candidate's induction of disease remission ...
    5-17-2013
  • Softening the Blow from FOLFOX Treatment
    ... The patient had Crohn's disease and terminal colorectal cancer, the world's third most common cancer with more than 1.2 million new cases worldwide each year, according to the ...
    5-15-2013
  • Biomarkers Take Center Stage
    ... with pools of unfractionated serum from patients with symptoms of inflammatory disease. ... Epigenetic Biomarkers Sometimes biomarkers are used not to find disease but to distinguish ...
    5-1-2013
  • Enzon Gives Up Hope to Sell
    treatment for anemia due to chronic kidney disease in adult patients on dialysis. ... (certolizumab pegol), a drug marketed by UCB for Crohn's disease and rheumatoid arthritis. ...
    4-24-2013
  • Biosimilars: 10 Drugs to Watch
    ... (ESA) for anemia due to chronic kidney disease (CKD) in patients on dialysis and ... reference product Epogen® /Procrit® in anemia associated with chronic kidney disease. ...
    4-22-2013
  • Epigenetics Opens New Avenues for DNA Research
    differences in traits, disease susceptibilities, and therapeutic responses. ... For example, 32 loci associated with Crohn's disease explain approximately 20% of the ...
    4-1-2013
  • Exploiting Folate Pathways to Treat Cancer
    ... Patients received vintafolide plus Doxil or Doxil alone until either disease progression ... type in inflammatory diseases like rheumatoid arthritis, Crohn's disease, and psoriasis. ...
    4-1-2013
  • Personalized Medicine: Translation of Concepts
    ... attempted with ex-vivo systems in areas such as rheumatoid arthritis and Crohn's disease. ... But now we would select patients with a similar disease pathway: e.g. Her-2 positive. ...
    3-19-2013
  • Biosimilars: Not So Far So Fast
    ... the E.U. in 2014. Celltrion has Korean approval for the product for treatment of rheumatoid arthritis, ulcerative colitis, Crohn's disease, ankylosing spondylitis, and psoriasis. ...
    3-15-2013
  • Receptos Licenses AbbVie Antibody for Co-Development
    RPC4046 in eosinophilic esophagitis (EoE), an FDA-designated orphan disease indication. ... that include the chronic skin disease hidradenitis suppurativa; peripheral ...
    3-13-2013
  • Small Firms Look Optimistically to Future
    VX-509 for autoimmune diseases, for example, may be a platform for multiple disease ... Late-stage projects are under way for cystic fibrosis, hepatitis C, and autoimmune disease ...
    3-1-2013
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    Journal Articles

  • Association Study of MICA-TM Polymorphism with Inflammatory Bowel...
    Arwa Kamoun, Dorra Bouzid, Nadia Mahfoudh, Ali Amouri, Lilia Gaddour, Faiza Hakim, Nabil Tahri, Hatem Masmoudi, Hafedh Makni
    Genetic Testing and Molecular Biomarkers
    Association Study of MICA-TM Polymorphism with Inflammatory Bowel Disease in South ... In CD, MICA-A6 was significantly increased in active disease patients when compared to ...
  • The lL-8 and IL-13 Gene Polymorphisms in Inflammatory Bowel Disease...
    Anna Walczak, Karolina Przybylowska, Lukasz Dziki, Andrzej Sygut, Cezary Chojnacki, Jan Chojnacki, Adam Dziki, Ireneusz Majsterek
    DNA and Cell Biology
    these polymorphic variants and ulcerative colitis (OR 2.05 for the -251 TA genotype and OR 1.47 for the -251 A allele) as well as Crohn disease (ORs 3.11 and 1.56, respectively). ...
  • Detection of MEFV Gene Mutations in Patients with Inflammatory...
    Erkan Yurtcu, Hale Gokcan, Ugur Yilmaz, Feride Iffet Sahin
    Genetic Testing and Molecular Biomarkers
    Detection of MEFV Gene Mutations in Patients with Inflammatory Bowel Disease Genetic Testing and Molecular Biomarkers Inflammatory bowel disease (IBD) with ulcerative colitis (UC) ...
  • Laparoscopic Appendectomy for Crohn's Disease of the Appendix...
    Jonathan S. Zager, Niraj J. Gusani, Brian G. Derubertis, Jason P. Shaw, Jarrod P. Kaufman, George Denoto
    Journal of Laparoendoscopic& Advanced Surgical Techniquesand Part B, Videoscopy
    Laparoscopic Appendectomy for Crohn's Disease of the Appendix Presenting as Acute Appendicitis Journal of Laparoendoscopic& Advanced Surgical Techniquesand Part B, Videoscopy

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