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Search Results - Copy Number Variation
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  • Comparative Genomics: Insights into Disease Susceptibility
    ... The key facets of genome sequencing analysis include: SNVs, copy-number variations (CNVs), ... such as determining cancer treatment or characterizing patterns of genetic variation. ...
    5-1-2013
  • Pathway Analysis to Decipher Data
    ... expression analyses, the fourth column represents copy number variation of EGFR. The right-most column represents Kaplan-Meier plots for "days to death" based on the EGFR data. ...
    4-15-2013
  • Advances in RNAi Tools and Technologies
    ... diluted with an increasing number of siRNA designs contained ... knockdown using low copy numbers that can result in ... This variation provides an additional layer of specificity. ...
    4-15-2013
  • Use of Digital PCR Ramping Up
    For each qPCR well, users receive the absolute copy number of DNA at cycle zero without the ... decrease in the coefficient of variation of pol copy number and a 10-fold ...
    2-15-2013
  • 8 Reasons Labs Rely on Digital and Quantitative PCR
    ... Enables high precision for gene expression, absolute quantitation or copy number variation analysis. The precision and reproducibility achievable with dPCR increases with the ...
    2-7-2013
  • Genomic Analysis Drives Biomarker Discovery
    ... Assessing structural changes and complex rearrangements, detecting copy number variation (CNV) with high sensitivity, and performing NGS at the single-cell level represent ...
    1-1-2013
  • Improving Molecular Genetic Testing
    ... To confirm the ploidy of targeted genes within each X-MAN cell line, Bio-Rad's Droplet Digital(tm) PCR platform was used, using gene-specific copy-number variation (CNV) assays run ...
    12-1-2012
  • iPSCs Reveal Somatic Copy Number Mosaicism in Skin Cells
    cells harbor copy number variations (CNVs), or DNA segments that are deleted or duplicated. ... cells, indicating that copy number variation/structural variation arises in these ...
    11-20-2012
  • CE Mark for NanoString's PAM50 Breast Cancer Test
    The firm's current portfolio of application-specific solutions includes kits for gene expression, copy number variation, and miRNA analysis. NanoString Technologies received a CE ...
    9-27-2012
  • Partnership Seeks Multiple Myeloma Biomarkers and Drugs
    myeloma field. "For this study, we will be collecting RNA-seq, SNP, and copy number variation data from our own patient samples," explains Sagar Lonial, M.D., director of ...
    9-24-2012
  • RT-qPCR Edging Out Other Methods
    ... to detect Plasmodium . "A number of such assays have been ... which have enough genetic variation to be problematic. ... takes advantage of the high copy numbers of rRNA in the ...
    8-1-2012
  • Harnessing the Promise of Array CGH
    The Agilent Human Genome CGH Microarray is a high-resolution tool for genome-wide DNA copy number variation profiling without amplification or complexity reduction. In addition to ...
    8-1-2012
  • Digital PCR System
    assays by enabling digital answers across a number of applications including low-frequency tumor allele detection, gene expression, copy number variation, and SNP measurement. ...
    7-1-2012
  • Enabling the Future of Plant Biology
    This, scientists say, is due to the high copy number and amplifying nature of transposable ... We work to define the limits of the species and how their genetic variation is ...
    6-13-2012
  • Reducing Uncertainty Surrounding Biosimilar Production
    products including changes in the variation range over time. ... Although biosimilar manufacturers face a number of ... Girard, adding that it is possible that copy versions of ...
    5-15-2012
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    Journal Articles

  • Copy Number Variation in Common Disease
    Oliver J. Brand, Stephen C.L. Gough
    Thyroid
    Copy Number Variation in Common Disease Thyroid
  • Organizational Variation of DYZ1 Repeat Sequences on the Human...
    Mohammed Mahidur Rahman, Anu Bashamboo, Aparna Prasad, Deepali Pathak, Sher Ali
    DNA and Cell Biology
    Typing of genomic DNA using DYZ1 as a probe showed an allele length and copy number ... showed discernible allelic variation between the two samples, indicating ...
  • The Clark Phaseable Sample Size Problem: Long-Range Phasing and...
    Bjarni V. HalldóRsson, Derek Aguiar, Ryan Tarpine, Sorin Istrail, Bjarni V Halldorsson
    Journal of Computational Biology
    We also study a related problem that connects copy number variation with phasing algorithm success. A loss of heterozygosity (LOH) event is when, by the laws of Mendelian ...
  • Identification and Frequency Estimation of Inversion Polymorphisms...
    Suzanne S. Sindi, Benjamin J. Raphael
    Journal of Computational Biology
    are increasingly recognized as an important contributor to human genetic variation. Copy number variants are readily measured via array-based techniques like comparative ...

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