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  • Takeover Targets: Who Is First on the List?
    ... and branch retinal vein occlusion (BRVO); sarilumab (REGN88) for rheumatoid arthritis; and alirocumab (REGN727) for LDL cholesterol reduction. Why attractive: In a word, Eylea. ...
    9-24-2013
  • Isis Wins $2M Milestone Payment from GSK for Antisense Drug Candidate
    The company's lead product, the once-weekly injection anti-LDL cholesterol drug Kynamro, is being commercialized by collaboration partner Genzyme for patients with the rare genetic ...
    7-30-2013
  • Study: Diabetes Drug Helps Mice Live Longer, More Healthfully
    with caloric restriction-like improved physical performance, increased insulin sensitivity, and reduced low-density lipoprotein and cholesterol levels-without reducing intake. ...
    7-29-2013
  • Odd Science: Taste-Signaling Proteins Play Crucial Role in Sperm...
    to a class of drugs that frequently are prescribed to treat lipid disorders such as high blood cholesterol or triglycerides -was removed from the animals' diet. As a result, Dr. ...
    7-1-2013
  • Telomere-Guarding Gene May Also Protect Against Obesity
    Blasco and her colleagues found that mice lacking RAP1 also "suffer from metabolic syndrome, accumulate abdominal fat, and present high glucose and cholesterol levels, amongst ...
    6-21-2013
  • Techne Buys Bionostics for $104M
    launched coagulation device control products, and is developing controls for other growing diagnostic uses, particularly cholesterol and HbA1c point-of-care testing (POCT) devices. ...
    6-18-2013
  • ReGen Med: Straight Out of Mythology
    ... debris and exerting cardioprotective effects that include oxidized LDL uptake and cholesterol efflux. "It is this combination of secreted factors and direct cell activities that ...
    6-11-2013
  • Deciphering the Mysteries in Lipid Biology
    ... Sterol Analytics Cholesterol is the most well-known member of sterol family of lipids, and ... And yet, until now we did not possess a robust ability to evaluate all cholesterol ...
    6-1-2013
  • AstraZeneca Acquires Omthera in Up to $443M Deal
    Omthera last year reported positive results from two Phase III trials evaluating the efficacy of Epanova in lowering very high triglycerides and in reducing non-HDL cholesterol in ...
    5-28-2013
  • Synthetic Sea Anemone Toxin Could Be Newest Weapon in Obesity...
    white fat deposits, fatty liver, blood cholesterol and blood sugar by activating calorie-burning brown fat, suppressing inflammation of white fat and augmenting liver function. ...
    5-28-2013
  • Improving Proteomics Approaches
    ... The cell membrane is chemically heterogeneous (left). Lipid rafts, enriched in cholesterol and exhibiting local lipid ordering (light gray), sequester certain kinds of membrane ...
    5-15-2013
  • Study Points to Potential Biomarker for Atherosclerosis
    Thorin and his colleagues also found that angptl2, which is undetectable in young mice, increases with age in healthy animals, and prematurely so in those with high cholesterol and ...
    5-14-2013
  • Rethinking APOE's Role in Alzheimer's
    APOE is involved in the metabolism of fats, cholesterol, and vitamins throughout the body. Scientists have identified three different forms of the gene that each make a slightly ...
    5-8-2013
  • "GEN 10" Award Winners Announced
    myeloid leukemias Anne Thiel, Northwestern University, Abstract: Point-of-care cholesterol testing on a bioelectronic platform Srishti Tibrewala, Northwestern University, ...
    4-22-2013
  • Merck & Co. Picks Up Exclusive Option on Xenon CV Drugs
    year-vorapaxar for acute coronary syndrome chest pain caused by coronary artery disease, and K-524A (tredaptive), for LDL (bad cholesterol) to reduce incidence of vascular events. ...
    4-17-2013
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    Journal Articles

  • Cholesterol Dependence of HTLV-I Infection
    Matthew M. Wielgosz, Daniel A. Rauch, Kathryn S. Jones, Frank W. Ruscetti, Lee Ratner
    AIDS Research and Human Retroviruses
    Cholesterol Dependence of HTLV-I Infection AIDS Research and Human Retroviruses Cholesterol-rich plasma membrane microdomains are important for entry of many viruses, including ...
  • The Cholesterol-Lowering Effect of Coconut Flakes in Humans with...
    Trinidad P. Trinidad, Anacleta S. Loyola, Aida C. Mallillin, Divinagracia H. Valdez, Faridah C. Askali, Joan C. Castillo, Rosario L. Resaba, Dina B. Masa
    Journal of Medicinal Food
    The Cholesterol-Lowering Effect of Coconut Flakes in Humans with Moderately Raised Serum Cholesterol Journal of Medicinal Food This study investigated the effect of coconut flakes ...
  • Cellular Cholesterol Involvement in Src, PKC, and p38/JNK Transduction...
    Mariateresa Vitiello, Emiliana Finamore, Katia Raieta, Aikaterini Kampanaraki, Eleonora Mignogna, Emilia Galdiero, Marilena Galdiero
    Journal of Interferon & Cytokine Research
    Cellular Cholesterol Involvement in Src, PKC, and p38/JNK Transduction Pathways by Porins ... Cholesterol confined in lipid domains is a crucial component required by microorganisms, ...
  • Cholesterol Screening for Women: Who Is "At-Risk"?
    Cheryl L. Robbins, Patricia M. Dietz, Shanna Cox, Elena V. Kuklina
    Journal of Women's Health
    Cholesterol Screening for Women: Who Is "At-Risk"? Journal of Women's Health Background: High cholesterol often precedes cardiovascular disease (CVD) and guidelines recommend ...

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