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Search Results - Chemotherapy
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  • Vical Scraps Melanoma Candidate After Phase III Failure
    The company said Allovectin failed to demonstrate statistically significant improvement vs. first-line chemotherapy for either the primary endpoint of objective response rate at 24 ...
    8-12-2013
  • Teva, Perrigo to Launch Generic Temodar
    Teva Pharmaceutical Industries and Perrigo said today they will launch a generic equivalent to the Merck chemotherapy cancer drug Temodar® (temozolomide). Temodar is indicated for ...
    8-12-2013
  • SCT Licenses Worldwide Rights to Prostate Cancer Stem Cell Assets
    The group has also shown that prostate cancer stem cells have an active resistance mechanism to conventional therapies such as radiotherapy and chemotherapy, which helps explain ...
    8-9-2013
  • Molecular Imaging Driving Development
    ... Predicting Therapeutic Response Targeted small molecules linked to chemotherapy drugs are ... small molecule targeting the folate receptor that is linked to a potent chemotherapy drug. ...
    8-1-2013
  • Servier to Develop Nerviano Anticancer Compounds in Up to $143...
    hepatocellular carcinoma (HCC), danusertib for solid tumors and chronic myeloid leukemia (CML), and milciclib for thymic carcinoma in patients previously treated with chemotherapy. ...
    7-30-2013
  • MolecularMD Licenses DDR2 Mutation Technology from Broad, Dana...
    cell carcinoma] patients, whose treatment options are currently limited to chemotherapy," MolecularMD's Greg Cox, Ph.D., director of licensing, said in a statement. "It's ...
    7-29-2013
  • Detecting, Tracking Brain Tumors with Digital PCR
    Patients may have a second operation to remove the tumor prior to beginning radiation therapy and chemotherapy, but none of these treatments are targeted to the specific molecular ...
    7-23-2013
  • AD Biotech, Quest to Codevelop Cancer-Fighting Immunotherapeutics
    Quest PharmaTech is a firm that is developing a portfolio of product candidates for the treatment of cancer by combining immunotherapeutic antibodies with chemotherapy, ...
    7-23-2013
  • RT-PCR: Ready for Prime Time?
    ... Makrigiorgos, Ph.D., from the Dana-Farber Cancer Institute. "Specifically, subclonal mutations in cancer cells may determine if a particular tumor is resistant to chemotherapy. ...
    7-23-2013
  • Drug Candidates on Trial
    ... metastatic castrate resistant prostate cancer who have not received prior chemotherapy. ... either VTX-2337 or placebo in combination with cetuximab, platinum, and 5-FU chemotherapy. ...
    7-22-2013
  • Ovarian Cancer Treatment Milestone Earns Array BioPharma $5M
    choice of standard chemotherapy treatments in 300 patients with recurrent or persistent LGSOC following at least one prior platinum-based chemotherapy regimen and no more ...
    7-2-2013
  • Genewiz Collaboration Spree Covers Ovarian Cancer Biomarkers...
    This research collaboration will reportedly enable analysis of ovarian cancer samples for the identification of biomarkers predicting prognosis and chemotherapy outcomes for ...
    6-28-2013
  • Bayer, Seattle Genetics Launch Up to $520M ADC Collaboration
    once inside targeted cancer cells, with the goal of sparing nontargeted cells, thus reducing many toxic effects of traditional chemotherapy while enhancing antitumor activity. ...
    6-25-2013
  • Debiopharm, Alacrita Eye More Massachusetts Deals
    Last year, Debiopharm and Curis launched a Phase I/II clinical trial (NCT01714037) of the since-renamed Debio 0932, in combination with chemotherapy regimens in patients with ...
    6-24-2013
  • HIV-Derived Antibacterial Compounds Could Help Fight Multidrug...
    In a new Antimicrobial Agents and Chemotherapy report, Pittsburgh's Ronald Montelaro, Ph.D., and his colleagues show that these agents, engineered cationic antimicrobial peptides ...
    6-20-2013
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    Journal Articles

  • Safety and Efficacy of a Genetic Vaccine targeting Telomerase...
    Alessandra Gavazza, George Lubas, Arthur Fridman, Daniela Peruzzi, Joseph A Impellizeri, Laura Luberto, Emanuele Marra, Giuseppe Roscilli, Gennaro Ciliberto, Luigi Aurisicchio
    Human Gene Therapy and Part B: Methods
    Safety and Efficacy of a Genetic Vaccine targeting Telomerase plus Chemotherapy for the ... (LSA) in comparison with historical controls when combined with COP chemotherapy regimen. ...
  • Regimen specific effects of RNA-modified chimeric antigen receptor...
    David Maxwell Barrett, Xiaojun Liu, Shuguang Jiang, Carl H June, Stephan A Grupp, Yangbing Zhao
    Human Gene Therapy and Part B: Methods
    We tested the hypothesis that multiple infusions of RNA CAR CTLs preceded by lymphodepleting chemotherapy could mediate improved survival and sustained anti-tumor responses in a ...
  • Factors Influencing Health Related Quality of Life in Cancer...
    Erin Wong, Edward Chow, Liying Zhang, Gillian Bedard, Kinsey Lam, Alysa Fairchild, Vassilios Vassiliou, Mohamed A. Alm El-Din, Reynaldo Jesus-Garcia, Aswin Kumar, Fabien Forges, Ling-Ming Tseng, Ming-Feng Hou, Wei-Chu Chie, Andrew Bottomley
    Journal of Palliative Medicine
    Further study focusing on factors such as current treatment (chemotherapy, bisphosphonates, and radiotherapy) and spiritual well-being may identify additional influences. ...
  • Antiproliferative Activities of Lesser Galangal ( Alpinia officinarum...
    Samson N. Omoregie, Felix O. Omoruyi, Vincent F. Wright, Lemore Jones, Paul V. Zimba
    Journal of Medicinal Food
    Acute monocytic leukemia (AML M5 or AMoL) is one of several types of leukemia that are still awaiting cures. The use of chemotherapy for cancer management can be harmful to normal ...

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