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Search Results - Cell-Line Development
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  • Still a Place for Steel and Glass
    ... But Mirro is optimistic. "Years of development, and ample comparative data, show process comparability and cell-line compatibility for stainless steel and single-use bioreactors," ...
    8-1-2013
  • PolyTherics Expands Drug Development Services with Antitope Purchase
    of biologics, technologies for immunogenicity screening, technologies to re-engineer antibodies and proteins to reduce their immunogenicity, and cell-line development. ...
    7-26-2013
  • Biosimilar Marriage Ends in Divorce for Teva, Lonza
    on what he called the company's core expertise in contract manufacturing and cell-line development: "In our assessment those investments in biosimilars will require more capital ...
    7-25-2013
  • Targeting Deranged Metabolism to Treat Cancer
    ... cells and suggested novel avenues for development of anticancer therapeutics which are ... erythroleukemia cell line and primary human acute myelogenous leukemia cells in vitro. ...
    7-1-2013
  • New CHO Cell Lines on the Horizon for Hisun
    cell-line engineering," Haibin Wang, svp of Hisun Pharmaceuticals, said. "Cell-line development has yet to match the gains made in media and feed technology development," ...
    6-18-2013
  • Rapid Mass Analysis of Intact Proteins
    ... chains, produced by the mouse myeloma cell line, MOPC21. The quality of the MALDI data ... are notably in demand. | Applications Development Manager Shannon Cornett, Ph.D.
    6-15-2013
  • Lights, Camera, and Lots of Cellular Action
    An H9 embryonic stem cell line stably transfected with a GFP-Oct4 promoter construct 65h ... Technology advances bring new sets of challenges, including the development of stable ...
    6-1-2013
  • Targeting Deranged Metabolism to Treat Cancer
    ... cells and suggested novel avenues for development of anticancer therapeutics which are ... erythroleukemia cell line and primary human acute myelogenous leukemia cells in vitro. ...
    5-30-2013
  • RuiYi Licenses mAb Development to China's Genor
    The agreement comes just two days after RuiYi announced it would accelerate development of a cell line for RYI-008 by using the CHEF1® high-productivity expression plasmid of CMC ...
    5-16-2013
  • Highlights from AACR
    In one, Grooby et al., described an siRNA screen using a reporter cell line in which ... and validation, and for assay development, disease modeling, and compound profiling. ...
    5-15-2013
  • RuiYi, CMC Collaborate to Speed mAb Development
    CMC Biologics will use its CHEF1® high-productivity expression plasmid to accelerate development of a cell line for RuiYi's monoclonal antibody RYI-008, under a collaboration ...
    5-14-2013
  • Biologically Relevant Laminins
    ... in IVF clinics and enables ES cell-line generation without destruction of the embryo. ... for the gap between academic stem cell research and development of human cell therapy. ...
    5-1-2013
  • Human iPSC-Derived Hepatocytes
    ... limitations from development while focusing on safer and more in vivo-stable therapeutics. ... hepatocellular carcinoma derived HepG2 cell line does not respond to aflatoxin over the ...
    5-1-2013
  • Performing "Informative Clinical Trials" in Mice
    The high costs and failure rates of cancer drug development underscore the need for novel ... Combined with data from cancer cell-line xenograft in vivo models, these PDTX models can ...
    4-17-2013
  • Pathway Analysis to Decipher Data
    ... Encyclopedia, which is a compilation of cell line-specific data on gene expression, ... His group envisions that this unique dataset will enhance the design and development of ...
    4-15-2013
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    Journal Articles

  • sFRP1 Inhibits Epithelial-Mesenchymal Transition in A549 Human...
    Jin Ren, Rui Wang, Guichun Huang, Haizhu Song, Yitian Chen, Longbang Chen
    Cancer Biotherapy and Radiopharmaceuticals
    in A549 Human Lung Adenocarcinoma Cell Line Cancer Biotherapy and ... Wnt pathway is identified as a key regulator of normal tissue development, and its ...
  • Isolation and characterization of a spontaneously immortalized...
    Andrea Zamperone, Stefano Pietronave, Simone Merlin, Donato Colangelo, Gabriella Ranaldo, Enzo Medico, Federica Di Scipio, Giovanni Nicolao Berta, Antonia Follenzi, Maria Prat
    Stem Cells and Development
    Isolation and characterization of a spontaneously immortalized multipotent mesenchymal cell line derived from mouse subcutaneous adipose tissue Stem Cells and Development
  • NVP-BEZ235, Dual Phosphatidylinositol 3-Kinase/Mammalian Target...
    Wenjie Zhu, Weijiang Fu, Likuan Hu
    Cancer Biotherapy and Radiopharmaceuticals
    Radiosensitivity of Prostate Cancer Cell Line PC-3 Cancer Biotherapy and ... pathway may account for development of radioadaptation and is not rare in prostate cancer. ...
  • Evaluation of a Range of Anti-Proliferative Assays for the Preclinical...
    Suja Elizabeth George, Rosaleen J. Anderson, Anne Cunningham, Michael Donaldson, Paul W. Groundwater
    ASSAY and Drug Development Technologies
    ASSAY and Drug Development Technologies Abstract Established treatments for psoriasis are ... We have also validated the use of the HaCaT cell line as a representative of the ...

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