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Search Results - Cardiomyocytes
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  • High-Content Screening for Identifying miRNAs Inducing Cardiac...
    identification of microRNAs that promote proliferation of neonatal cardiomyocytes. ... the impact of pharmacologic compounds on cardiomyocytes derived from stem cell sources. ...
    6-25-2013
  • Stem Cell Science Advances
    ... To circumvent the problem his lab has derived cardiomyocytes from human skin cells (hiPSC-CMs). "The cardiac cell that we obtain beats on a dish so we can measure several ...
    6-11-2013
  • Biologically Relevant Laminins
    ... For instance, laminin-211 (LN-211) is expressed in heart muscle to support cardiomyocytes ... expanded and turned into mature cardiomyocytes simply by changing the laminin matrix ...
    5-1-2013
  • Gene Critical for Heart Regeneration
    The scientists also found that overexpression of Meis1 in cardiomyocytes decreased neonatal myocyte proliferation and inhibited neonatal heart regeneration. This new finding ...
    4-18-2013
  • Advertorial: ACEA Biosciences
    ... Figure 2 shows how the same readout can be applied to functional detection of iPS-derived cardiomyocytes and detection of compounds, which may cause arrhythmia. These two ...
    4-15-2013
  • Predicting Drug Toxicity in Humans
    Idiosyncratic drug toxicity is human-specific, occurring as a rare event ( Instead, human cells are being used (e.g., induced pluripotent stem cells [iPS]) to yield cardiomyocytes ...
    4-1-2013
  • High-Content Screening Broadens Its Scope
    ... assays using stem cell-derived cardiomyocytes, hepatocytes, and neurons can ... Into the Clinic GE Healthcare CytivaT human stem cell derived cardiomyocytes: Inset images ...
    2-1-2013
  • Overcoming Roadblocks in Cell-Based Assay Research
    pluripotent stem) cells, such as cardiomyocytes, hepatocytes, and neuronal cells are ... Scale bar = 70 µm. iPS-derived cells such as hepatocytes, cardiomyocytes, and neural ...
    2-1-2013
  • New Technological Advances in Stem Cell Research
    starting stem cell types and differentiated progeny, e.g., hepatocytes, neurons, cardiomyocytes, and osteoblasts from human and mouse embryonic and mesenchymal stem cells. ...
    1-15-2013
  • Stem Cell Tech Gets Boost from Academic-Industry Partnership
    These induced pluripotent stem cells offer a supply of different kinds of human cell such as cardiomyocytes, endothelial cells, or neurons that can be used for a broad range of in ...
    12-5-2012
  • Ducted Respiratory Chamber Bioreactors
    ... Naturally induced oxygen levels and cell growth in the DRC are depicted in Figure 3 . A series of DRC bioreactors were seeded with neonatally derived cardiomyocytes, 10 6 cells per ...
    11-1-2012
  • Cellular Therapy Wave Finally Cresting
    Stem cells are also finding utility in the generation of cell types that are sentinels for in vivo drug toxicity, such as hepatocytes and cardiomyocytes. Cellular therapeutics, the ...
    11-1-2012
  • Featured Video: Man-Made Jellyfish
    You may remember GEN reporting on Harvard and CalTech's man-made jellyfish-like creation made from rat cardiomyocytes. (Don't remember? Check out Building a Rat That Swims Like a ...
    10-3-2012
  • Fine-Tuning Cell-Based Assays
    ... Cardiomyocytes from Adult Stem Cells The stem cell division of Cellectis is working with ... Cardiomyocytes are an ideal focus for iPS cell development, because it is very difficult ...
    9-15-2012
  • Closing the Research Therapeutic Loop
    ... types of somatic cells, such as cardiomyocytes, endothelial cells and pan neuron ... described using human iPSC-derived cardiomyocytes to evaluate the cardiotoxic effect of ...
    9-15-2012
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    Journal Articles

  • Human Embryonic Stem Cell-Derived Cardiomyocytes Migrate in Response...
    Kara White Moyes, Christopher G. Sip, Willimark Obenza, Emily Yang, Cody Horst, Robert E. Welikson, Stephen D. Hauschka, Albert Folch, Michael A. Laflamme
    Stem Cells and Development
    Human Embryonic Stem Cell-Derived Cardiomyocytes Migrate in Response to Gradients of Fibronectin and Wnt5a Stem Cells and Development
  • Human Amniotic Mesenchymal Stem Cell-Derived Induced Pluripotent...
    Xiaohu Ge, I-Ning E. Wang, Ildiko Toma, Vittorio Sebastiano, Jianwei Liu, Manish J. Butte, Renee A. Reijo Pera, Phillip C. Yang
    Stem Cells and Development
    (MiPSCs) successfully underwent robust cardiac differentiation to generate cardiomyocytes. ... genes and mature cardiac phenotype, and contractile force comparable to cardiomyocytes. ...
  • Activation of Akt Rescues Endoplasmic Reticulum Stress-Impaired...
    Yingmei Zhang, Zhi Xia, Karissa H. La Cour, Jun Ren
    Antioxidants & Redox Signaling
    In vitro ER stress induction in murine cardiomyocytes upregulated the ER stress proteins Gadd153, GRP78, and phospho-eIF2a, and promoted reactive oxygen species production, ...
  • 5-Azacytidine Induces Cardiac Differentiation of Human Umbilical...
    Qian Qian, Hui Qian, Xu Zhang, Wei Zhu, Yongmin Yan, Shengqin Ye, Xiujuan Peng, Wei Li, Zhe Xu, Lingyun Sun, Wenrong Xu
    Stem Cells and Development
    (5-Aza) induces differentiation of mesenchymal stem cells (MSCs) into cardiomyocytes. ... that 5-Aza induces human bone marrow-derived MSCs to differentiate into cardiomyocytes. ...

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