Current Issue

View Larger Image

Past Issues Free Subscriptions
Sponsored
Keywords



Search Results - CLL
 More »

  • Pharma Touting Phase II/III Wins in Run-Up to ASCO
    drug GA101 for the treatment of chronic lymphocytic leukemia (CLL). Presenting results from its CLL11 trial conducted in collaboration with the German CLL Study Group, ...
    5-16-2013
  • Pharmacyclics Achieves Another $50M Milestone
    with treatment-naïve chronic lymphocytic leukemia/small lymphocyctic lymphoma (CLL/SLL). ... for patients with relapsed or refractory CLL/SLL, enrolled its fifth patient; after, ...
    4-11-2013
  • Epigenetics: Promising Field Delivers
    ... the chronic lymphocytic leukemia (CLL) genome project, Dr. Martin-Subero and colleagues examined DNA methylation changes in 139 patients with CLL. The availability of the ...
    1-15-2013
  • HIV Vector Licks Leukemia
    Once T cells start expressing the CAR, they focus all of their killing activity on cells that express CD19, which includes CLL and ALL tumor cells, and normal B cells. All other ...
    12-10-2012
  • Tissue Expertise Begat Biospecimens CRO
    ... Cureline collects biospecimens from patients with all types of hematologic malignancies, such as AML and CLL, in both chronic and crisis stages of the disease. Cancer blood, bone ...
    11-1-2012
  • The Big Idea for 2009 as Discussed at J.P. Morgan
    Products for CNS include Provagil for wakefulness, Gabitril for seizures; in Cancer Treanda for CLL and NHL as well as Actiq for pain in opiate-tolerant cancer patients. CEPH ...
    8-13-2012
  • Five Is Lucky Number for Pharmacyclics
    leukemia or small lymphocytic lymphoma (CLL/SLL) has enrolled its fifth patient. ... is anticipated. "Data from patients with CLL/SLL observed in our Phase Ib/II program ...
    8-1-2012
  • Gene Therapy Briefs
    ... with chronic lymphocytic leukemia (CLL) showed that the gene immunotherapy is ... expresses chimeric humanized CD154, the ligand for CD40 which is expressed on CLL cells. ...
    6-1-2012
  • TG Therapeutics Licenses mAb-Based Drug to LFB Biotechnologies
    leukemia (CLL). It is being developed in multiple oncology and autoimmune indications and was granted orphan status in Europe and in the U.S. for B-cell CLL. Firm also ...
    3-2-2012
  • Inhibiting Cystine Transporter in Stromal Cells Cuts off Key...
    approach against chronic lymphocytic leukemia (CLL), including drug-resistant disease. ... production of the antioxidant GSH. Because CLL cells can't take up and utilize cystine on ...
    2-15-2012
  • Despite Flat Budget, NIH's TRND Program Tries to Spark Interest...
    the other on chronic lymphocytic leukemia (CLL), have advanced to clinical trials: Phase I ... For the CLL project, TRND joined with Kansas University's Institute for Advancing Medical ...
    1-27-2012
  • TrovaGene to Buy MultiGen's CLIA Lab to Bolster Infectious Disease...
    the SF3B1 splicing factor, which have been shown to be associated with disease progression and chemotherapy response in patients suffering from chronic lymphocytic leukemia (CLL). ...
    1-6-2012
  • TrovaGene Gains Rights to Mutations Associated with Chronic Lymphocyti...
    progression and chemotherapy response in patients with chronic lymphocytic leukemia (CLL). ... diagnostic markers beyond TP53 disruptions and NOTCH1 mutations in CLL patients. ...
    1-3-2012
  • Abbott, Emergent Terminate Co-Development Deal for B-Cell Cancers
    potential treatment for chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL). ... bendamustine as a treatment for relapsed CLL. Initiation of this study has triggered a ...
    12-28-2011
  • Celgene Nixes Revlimid Prostate Cancer Trial
    (MDS), chronic lymphocytic leukemia (CLL), and non-Hodgkin lymphoma (NHL). "We have ... as a treatment for other types of MDS, CLL, and NHL. Celgene also has a Phase II solid ...
    11-23-2011
  • More »

    Journal Articles

  • Use of Retroviral Markers to Identify Efficacy of Purging and...
    Albert Deisseroth, Hagop Kantarjian, Richard Champlin, Fernando Cabanillas, Michael Keating, Chris Reading, Borje Andersson, David Claxton, Bud Robertson, Susan Escudier, Michael Andreeff, Susan O'Brien, Steven Kornblau, Debra Ellerson, Elie Hanania, Siqing Fu
    Human Gene Therapy and Part B: Methods
    B Cell Neoplasms (Follicular Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia (CLL) Patients). The University of Texas M.D. Anderson Cancer Center Human Gene Therapy and ...
  • Analysis of p53 Tumor Suppressor Pathway Genes in Chronic Lymphocytic...
    Mustafa Isin, Mustafa Yenerel, Melih Aktan, Nur Buyru, Nejat Dalay
    DNA and Cell Biology
    peripheral blood of patients with chronic lymphocytic leukemia (CLL) and healthy controls. ... p14ARF, and HDM2 genes are associated with CLL. Elucidation of the mutual interactions at ...
  • In Vitro Screening for Synergism of High-Linear Energy Transfer...
    Katia Vandenbulcke, Hubert Thierens, Filip De Vos, Jan Philippé, Fritz Offner, Ann Janssens, Christos Apostolidis, Alfred Morgenstern, Klaus Bacher, Virginie de Gelder, Rudi A. Dierckx, Guido Slegers
    Cancer Biotherapy and Radiopharmaceuticals
    Objectives: The aim of this study was to assess the response of B-Cell chronic lymphocytic leukemia (B-CLL) cells in vitro after treatment with chemotherapy (cisplatin, ...
  • The Lysosomotropic Agent, Hydroxychloroquine, Delivered in a...
    Eduardo Mansilla, Gustavo H. Marin, Luis Nuñez, Hugo Drago, Flavio Sturla, Carol Mertz, Luis Rivera, Thomas Ichim, Neil Riordan, Clemente Raimondi
    Cancer Biotherapy and Radiopharmaceuticals
    B-chronic lymphocytic leukemia (B-CLL) cells in vitro, three of them ... suitable for selective drug delivery to B-CLL cells and produce a strong apoptotic effect ...

GEN Webinars

View »

GEN Web Briefs

View »

GEN Poll

More » Poll Results » Archive »

Genome Sequencing and Patient Autonomy

Do you think ACMG’s recent recommendations for reporting incidental clinical sequencing results undermine patient autonomy?

Suggest a Poll