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Search Results - CLL
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  • Genentech Trumpets Phase III Results for CLL Candidate
    blood cancer chronic lymphocytic leukemia (CLL), saying the drug candidate plus ... Genentech did not detail what PFS was in the second stage of its CLL 11 study, saying ...
    7-24-2013
  • Celgene Halts a Phase III B-Cell CLL Trial Because of Deaths
    with B-cell chronic lymphocytic leukemia (CLL), plus comorbidities that precluded ... Revlimid is not approved as a CLL treatment. Celgene today said that after a consultation ...
    7-18-2013
  • Mayo Clinic, Cancer Genetics Form Diagnostics JV
    The company also markets MatBA diagnostics for chronic lymphocytic leukemia (CLL) and small lymphocytic leukemia (SLL). Joint venture will develop, commercialize cancer tests based ...
    5-22-2013
  • Pharma Touting Phase II/III Wins in Run-Up to ASCO
    drug GA101 for the treatment of chronic lymphocytic leukemia (CLL). Presenting results from its CLL11 trial conducted in collaboration with the German CLL Study Group, ...
    5-16-2013
  • Pharmacyclics Achieves Another $50M Milestone
    with treatment-naïve chronic lymphocytic leukemia/small lymphocyctic lymphoma (CLL/SLL). ... for patients with relapsed or refractory CLL/SLL, enrolled its fifth patient; after, ...
    4-11-2013
  • Epigenetics: Promising Field Delivers
    ... the chronic lymphocytic leukemia (CLL) genome project, Dr. Martin-Subero and colleagues examined DNA methylation changes in 139 patients with CLL. The availability of the ...
    1-15-2013
  • HIV Vector Licks Leukemia
    Once T cells start expressing the CAR, they focus all of their killing activity on cells that express CD19, which includes CLL and ALL tumor cells, and normal B cells. All other ...
    12-10-2012
  • Tissue Expertise Begat Biospecimens CRO
    ... Cureline collects biospecimens from patients with all types of hematologic malignancies, such as AML and CLL, in both chronic and crisis stages of the disease. Cancer blood, bone ...
    11-1-2012
  • The Big Idea for 2009 as Discussed at J.P. Morgan
    Products for CNS include Provagil for wakefulness, Gabitril for seizures; in Cancer Treanda for CLL and NHL as well as Actiq for pain in opiate-tolerant cancer patients. CEPH ...
    8-13-2012
  • Five Is Lucky Number for Pharmacyclics
    leukemia or small lymphocytic lymphoma (CLL/SLL) has enrolled its fifth patient. ... is anticipated. "Data from patients with CLL/SLL observed in our Phase Ib/II program ...
    8-1-2012
  • Gene Therapy Briefs
    ... with chronic lymphocytic leukemia (CLL) showed that the gene immunotherapy is ... expresses chimeric humanized CD154, the ligand for CD40 which is expressed on CLL cells. ...
    6-1-2012
  • TG Therapeutics Licenses mAb-Based Drug to LFB Biotechnologies
    leukemia (CLL). It is being developed in multiple oncology and autoimmune indications and was granted orphan status in Europe and in the U.S. for B-cell CLL. Firm also ...
    3-2-2012
  • Inhibiting Cystine Transporter in Stromal Cells Cuts off Key...
    approach against chronic lymphocytic leukemia (CLL), including drug-resistant disease. ... production of the antioxidant GSH. Because CLL cells can't take up and utilize cystine on ...
    2-15-2012
  • Despite Flat Budget, NIH's TRND Program Tries to Spark Interest...
    the other on chronic lymphocytic leukemia (CLL), have advanced to clinical trials: Phase I ... For the CLL project, TRND joined with Kansas University's Institute for Advancing Medical ...
    1-27-2012
  • TrovaGene to Buy MultiGen's CLIA Lab to Bolster Infectious Disease...
    the SF3B1 splicing factor, which have been shown to be associated with disease progression and chemotherapy response in patients suffering from chronic lymphocytic leukemia (CLL). ...
    1-6-2012
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    Journal Articles

  • Interleukin-12 Inhibits Apoptosis in Chronic Lymphatic Leukemia...
    S. Schuhknecht, S. Duensing, I. Dallmann, J. Grosse, M. Reitz, J. Atzpodien
    Cancer Biotherapy and Radiopharmaceuticals
    Interleukin-12 Inhibits Apoptosis in Chronic Lymphatic Leukemia (CLL) B Cells Cancer ... the effect of interleukin-12 on apoptosis of chronic lymphatic leukemia (CLL) B cells. ...
  • Autologous Antileukemic Immune Response Induced by Chronic Lymphocytic...
    Satoshi Takahashi, Raphael F. Rousseau, Patricia Yotnda, Zhuyong Mei, Gianpietro Dotti, Donna Rill, Richard Hurwitz, Frank Marini, Michael Andreeff, Malcolm K. Brenner
    Human Gene Therapy and Part B: Methods
    Although the B cells of chronic lymphocytic leukemia (B-CLL cells) express both ... To stimulate CLL-specific immune responses, we sought to transfer the human CD40 ligand ...
  • Letter to the Editor: Community-Based Phase II Trial of PCR for...
    Neil E. Kay, Tait D. Shanafelt, John C. Byrd, Michael R. Grever
    Cancer Biotherapy and Radiopharmaceuticals
    Letter to the Editor: Community-Based Phase II Trial of PCR for CLL/SLL Patients Cancer Biotherapy and Radiopharmaceuticals
  • Bystander Transfer of Functional Human CD40 Ligand from Gene...
    Ettore Biagi, Eric Yvon, Gianpietro Dotti, Persis J. Amrolia, Satoshi Takahashi, Uday Popat, Frank Marini, Michael Andreeff, Malcolm K. Brenner, Raphaël F. Rousseau
    Human Gene Therapy and Part B: Methods
    B-chronic lymphocytic leukemia (B-CLL), because it may increase the capacity of ... Ten B-CLL samples were cocultured with MRC-5 fibroblasts (a human embryonic lung cell ...

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