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  • Novel CHO Suspension Cell Cultivation
    This study focuses on the cultivation of CHO suspension cells in fed-batch mode using ... Day -6: Inoculum production with CHO suspension cells (CHO XM111-10) in shake flasks. ...
    8-1-2013
  • New CHO Cell Lines on the Horizon for Hisun
    to optimize Horizon's newly engineered CHO bioproduction cell line for commercial use. ... GS-negative CHO cell lines, Horizon and Hisun say, work well for stringent selection of ...
    6-18-2013
  • Stem Cell Science Advances
    ... He takes issue with the pharmaceutical industry's reliance on Chinese hamster ovary (CHO) ... genes," he pointed out. "Relying on CHO cells expressing HERG channels can lead to ...
    6-11-2013
  • Testing for Residual Host Cell Protein & DNA
    cells like Chinese hamster ovary (CHO), are used to express proteins that ... for quantitation of residual E. coli and CHO genomic DNA in recombinant biotherapeutics. ...
    5-1-2013
  • Meeting the Bioassay Challenge
    ... "Industry relies heavily on CHO and NSO cell lines for the production of biotherapeutics. ... Plus CHO and NSO are rodent cell lines. Rarely are such production cell lines relevant to ...
    3-15-2013
  • Betting on Baculovirus Expression
    ... of the polyethyleneimine (PEI) plasmid in HEK-293 and CHO cell lines. Plasmid-PEI complexes are readily taken up by HEK-293 cells and, to a lesser extent, into CHO cells. ...
    3-15-2013
  • Steric Exclusion Chromatography
    ... Most of the characterization work to date has been done with a Trastuzumab biosimilar produced in CHO cells at about 2 g/L, but Bevacizumab and Adalimumab biosimilars give ...
    3-15-2013
  • Genome Editing for R&D and Therapeutics
    ... SAFC has taken the ZFN technology a step further by utilizing it to create CHO cell lines ... SAFC currently provides both glutamine synthetase and dihydrofolate reductase knockout CHO ...
    3-1-2013
  • Cangene Inks $300+M Deal for Bankrupt Inspiration's IB1001
    ... from the Chinese hamster ovary, or CHO, host cells used to manufacture the therapy. ... events related to the development of antibodies to CHO protein reported to that time. ...
    2-20-2013
  • Plant-Based Protein Biomanufacturing
    ... that must be removed are specific to the plant species used, this is similar to removal of background contaminants specific to expression systems like E. coli or CHO cells. ...
    2-15-2013
  • Tying Up Loose Ends in Cell-Line Development
    ... Dr. Keresztessy's system of choice is the cGPS CHO-Sa CEMAX system from Cellectis. "However, we needed to construct our own version of the integration matrix vector provided by the ...
    2-1-2013
  • Streamlining Media Design
    extract that enhances CHO cell performance. The paper also examines the application of Sheffield brand cell-line specific supplements, the Sheff-CHO series, and the advantages ...
    2-1-2013
  • Baxter Reaps Benefits from Inspiration Bankruptcy
    ... proportion of individuals treated with IB1001 had developed antibodies to proteins from the Chinese hamster ovary, or CHO, host cells used to manufacture the therapy. ...
    1-24-2013
  • Apeiron Out-Licenses Antibody-Based Immunotherapy
    APN311 is a monoclonal chimeric antibody (ch14.18/CHO) targeting the GD2 antigen on neuroblastoma cells and is currently undergoing a randomized Phase III in Europe. The deal also ...
    1-18-2013
  • Single-Use Systems Entice Multiple Users
    ... GS Gene Expression is designed to work with the GS-CHO cell line, for which Lonza claims ... Lonza will continue to improve its platform processes, but with CHO v. 8, said Valentine, ...
    1-15-2013
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    Journal Articles

  • Impact of the "Diabetes Interactive Diary" Telemedicine System...
    Maria Chiara Rossi, Antonio Nicolucci, Giuseppe Lucisano, Fabio Pellegrini, Paolo Di Bartolo, Valerio Miselli, Roberto Anichini, Giacomo Vespasiani, on behalf of the DID St
    Diabetes Technology & Therapeutics
    and glulisine, not previously educated to CHO counting, were randomized to DID (Group A, ... Conclusions: DID is no more effective than traditional CHO counting education in reducing ...
  • Hybridoma Generation by In Vitro Immunization of Murine Splenocytes...
    Maddaly Ravi, Sukanya Shyama Sundar, Kaavya Krishna Kumar, Deepa Parvathi, Solomon F.D. Paul
    Hybridoma
    Hybridoma Generation by In Vitro Immunization of Murine Splenocytes with Cytosolic Proteins of Chinese Hamster Ovary (CHO) Mitotic Cells Hybridoma
  • Recombinant Fc-IL-18BPc Isoform Inhibits IL-18-Induced Cytokine...
    Kwangwon Hong, Kwangjun Oh, Siyoung Lee, Jaewoo Hong, Jida Choi, Areum Kwak, Dongjun Kang, Eunsom Kim, Seunghyun Jo, Hyunjhung Jhun, Soohyun Kim
    Hybridoma
    In this study, we have expressed and purified human Fc-IL-18BPa and c isoforms form CHO-DG44 cells and their biological activities were compared to each other. This is first time ...
  • The Influence of Depleted Glutathione Levels on the Photodynamic...
    E. Krajewska, M. Bryszewska, I.V. Chapman
    Photomedicine and Laser Surgery
    The Influence of Depleted Glutathione Levels on the Photodynamic Action of Zinc Phthalocyanine in CHO K1 Cells Photomedicine and Laser Surgery

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