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  • Scaleup Issues for Single Use and Steel
    and optimized a fed-batch process with CHO cell lines expressing a recombinant protein ... This molecule, bDtBPP, is detrimental to the growth of a number of strains of CHO cell ...
    10-15-2013
  • Identifying & Isolating High-Producer Clones
    Examples for such cell lines are the well-known Chinese hamster ovary (CHO) cells, human ... Although some media and supplements for serum-free single-cell cloning of CHO cells have ...
    10-15-2013
  • Advertorial: Fujifilm Diosynth Biotechnologies
    using our proprietary pAVEway(tm) and CHO cell line systems, to process development, ... from a wide range of cell types, including CHO, NS0, SP2/0, hybridoma, E. coli , Pichia ...
    10-1-2013
  • Progress in Protein Expression Technology
    ... but also due to the focus of such efforts on a single cell substrate platform, CHO cells," said Shyamsundar Subramanian, Ph.D., principal scientist and head of vaccine ...
    9-15-2013
  • Transfection Methods Evolving
    ... CHO Cell Bioproduction The majority of today's biotherapeutic proteins are produced in CHO cell lines adapted to suspension growth in chemically defined media formulations. ...
    9-1-2013
  • Exploiting Cells' Electrical Behavior
    analyzes individual CHO cells through radiofrequency actuation in a narrow capillary. ... DEP allows Braasch to map the trajectory of viability in CHO cells, including identifying ...
    9-1-2013
  • Novel CHO Suspension Cell Cultivation
    This study focuses on the cultivation of CHO suspension cells in fed-batch mode using ... Day -6: Inoculum production with CHO suspension cells (CHO XM111-10) in shake flasks. ...
    8-1-2013
  • New CHO Cell Lines on the Horizon for Hisun
    to optimize Horizon's newly engineered CHO bioproduction cell line for commercial use. ... GS-negative CHO cell lines, Horizon and Hisun say, work well for stringent selection of ...
    6-18-2013
  • Stem Cell Science Advances
    ... He takes issue with the pharmaceutical industry's reliance on Chinese hamster ovary (CHO) ... genes," he pointed out. "Relying on CHO cells expressing HERG channels can lead to ...
    6-11-2013
  • Testing for Residual Host Cell Protein & DNA
    cells like Chinese hamster ovary (CHO), are used to express proteins that ... for quantitation of residual E. coli and CHO genomic DNA in recombinant biotherapeutics. ...
    5-1-2013
  • Meeting the Bioassay Challenge
    ... "Industry relies heavily on CHO and NSO cell lines for the production of biotherapeutics. ... Plus CHO and NSO are rodent cell lines. Rarely are such production cell lines relevant to ...
    3-15-2013
  • Betting on Baculovirus Expression
    ... of the polyethyleneimine (PEI) plasmid in HEK-293 and CHO cell lines. Plasmid-PEI complexes are readily taken up by HEK-293 cells and, to a lesser extent, into CHO cells. ...
    3-15-2013
  • Steric Exclusion Chromatography
    ... Most of the characterization work to date has been done with a Trastuzumab biosimilar produced in CHO cells at about 2 g/L, but Bevacizumab and Adalimumab biosimilars give ...
    3-15-2013
  • Genome Editing for R&D and Therapeutics
    ... SAFC has taken the ZFN technology a step further by utilizing it to create CHO cell lines ... SAFC currently provides both glutamine synthetase and dihydrofolate reductase knockout CHO ...
    3-1-2013
  • Cangene Inks $300+M Deal for Bankrupt Inspiration's IB1001
    ... from the Chinese hamster ovary, or CHO, host cells used to manufacture the therapy. ... events related to the development of antibodies to CHO protein reported to that time. ...
    2-20-2013
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    Journal Articles

  • Stable Transformation of CHO Cells and Human NARP Cybrids Confers...
    S.J. Zullo, W.T. Parks, M. Chloupkova, B. Wei, H. Weiner, W.A. Fenton, J.M. Eisenstadt, C.R. Merril
    Rejuvenation Research
    Stable Transformation of CHO Cells and Human NARP Cybrids Confers Oligomycin Resistance ... To extend such studies, we modified the Chinese Hamster Ovary (CHO) mtDNA-located ATPase6 ...
  • A 219-mer CHO-Expressing Receptor-Binding Domain of SARS-CoV...
    Lanying Du, Guangyu Zhao, Chris CS Chan, Lin Li, Yuxian He, Yusen Zhou, Bo-Jian Zheng, Shibo Jiang
    Viral Immunology
    A 219-mer CHO-Expressing Receptor-Binding Domain of SARS-CoV S Protein Induces Potent ... RBD protein in Chinese hamster ovary (CHO)-K1 cells (RBD219-CHO), and tested its ...
  • Characterization of CHO Cells Stably Expressing a Gα 16/z Chimera...
    David C. New, Yung H. Wong
    ASSAY and Drug Development Technologies
    Characterization of CHO Cells Stably Expressing a Gα 16/z Chimera for High Throughput Screening of GPCRs ASSAY and Drug Development Technologies G protein-coupled receptors ...
  • Editorial Comment for Cho et al.
    Steven M. Lucas
    Journal of Endourologyand Part B, Videourology
    Editorial Comment for Cho et al. Journal of Endourologyand Part B, Videourology In the article presented by Cho et al, a trocarless technique for liver retraction during right ...

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