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  • Seasoned Drugs Offer Therapeutic Gold Mine
    ... GIST and renal cell carcinoma) for breast cancer brain metastasis, and chloroquine (previously used for malaria) for triple-negative brain metastases, now in Phase II trials. ...
    5-15-2013
  • Softening the Blow from FOLFOX Treatment
    ... Karlsson hoped to develop mangafodipir against the cardiotoxic side effects of anthracycline during breast cancer, only to see those plans waylaid by a series of mergers. ...
    5-15-2013
  • Sorrento, Igdrasol Secure Exclusive E.U. Distribution Rights...
    Cynviloq is already approved and marketed in several countries for indications including metastatic breast cancer, non-small-cell lung cancer, and ovarian cancer. Sorrento and ...
    5-14-2013
  • Lilly Halts Development of Lymphoma Drug After Phase III Failure
    ... Those two Phase III molecules are necitumumab, indicated for squamous non-small cell lung cancer; and ramucirumab for breast cancer, colorectal cancer, and gastric cancer. Lilly ...
    5-10-2013
  • Your Genes, Your Choice?
    You'd like to know more about your risk of developing the breast cancer that looms within your family's history. But, before learning this, consider: Do you also want to know ...
    5-9-2013
  • Companion Diagnostics: 52 Pick-Up
    ... Stratifies breast cancer patients who have had a priori invasive, localized breast carcinoma and who are lymph node-negative, according to risk for recurrence or disease-related ...
    5-9-2013
  • Cancer Diagnostics, Pushing the Boundaries
    In breast cancer, the Her2 oncogene is amplified or overexpressed in about 30% of breast cancers, but the correlation between Her2 gene expression and protein expression in these ...
    5-8-2013
  • Harnessing the Power of Kinase Inhibitors
    ... tested against the NCI-60 panel of human cancer cell lines and appear to significantly reduce the proliferation of a selected group of CNS, breast, and colon cancer cell lines. ...
    5-8-2013
  • The Tumor Microenvironment as a Drug Target, Part II
    In breast cancer, CAFs not only promote tumor progression but also induce therapeutic resistance. Continuous infiltration of a tumor mass by various fibroblast progenitors and ...
    5-7-2013
  • BMS Partners Again with Ambrx, in Up-to-$112M-and-Up ADC Collaboration
    Ambrx and BMS are among companies looking to develop ADCs: The list includes Roche (Genentech)'s Kadcyla, approved in February for breast cancer indications, and Seattle Genetics' ...
    5-3-2013
  • Turning Off Cancer's "Master Regulator"
    In the new study, Dr. Resar's team applied the same techniques to several strains of human breast cancer cells in the laboratory, including triple negative cells-those that lack ...
    5-3-2013
  • Two Proteins Found to Block Cancer Metastasis
    ... This peptide alone induced Tsp-1 in the bone marrow cells and effectively suppressed metastatic spread in the lungs in mouse models of breast and prostate cancer. This 5-amino acid ...
    5-1-2013
  • Biomarkers Take Center Stage
    ... It can take enormous datasets, sophisticated algorithms, and vast computational resources to tease out correlations that may prove useful in the clinic. Take breast cancer, a ...
    5-1-2013
  • GEN Congressional Hall of Fame
    ... Jim Gerlach R-PA BIO, Legislator of the Year, 2013 Pennsylvania Biotechnology Association, Federal Legislator of the Year, 2009 Linda Creed Breast Cancer Foundation, ACE Award, ...
    5-1-2013
  • Detecting Acquired Drug Resistance in Cancer
    TAm technology also allowed the scientists to monitor tumor dynamics, and track 10 concomitant mutations in plasma of a metastatic breast cancer patient over 16 months. This ...
    4-29-2013
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    Journal Articles

  • Impaired Vitamin D Activation and Association with CYP24A1 Haplotypes...
    Marissa Penna-Martinez, Elizabeth Ramos-Lopez, Julienne Stern, Heinrich Kahles, Nora Hinsch, Martin-Leo Hansmann, Ivan Selkinski, Frank Grünwald, Christian Vorländer, Wolf O. Bechstein, Stefan Zeuzem, Katharina Holzer, Klaus Badenhoop
    Thyroid
    Background: Common polymorphisms of the vitamin D receptor gene have been reported to affect the risk of breast, colon, prostate, and differentiated thyroid cancer (DTC), but ...
  • Factors Associated with the Development of New Onset Diffuse...
    Sang Soo Kim, Seong-Jang Kim, Young Tae Bae, Jee Yeon Lee, Bo Hyun Kim, Yong Ki Kim, In Joo Kim
    Thyroid
    Factors Associated with the Development of New Onset Diffuse Thyroid F18-Fluorodeoxyglucose Uptake After Treatment of Breast Cancer in Patients Without a History of Thyroid Disease ...
  • The Biochemistry, Chemistry and Physiology of the Isoflavones...
    Stephen Barnes
    Lymphatic Research and Biology
    inhibit metastasis. These various properties may explain the much lower incidence of hormonally-dependent breast cancer in Asian populations compared to Americans and Europeans.
  • Bioelectrical Impedance for Detecting Upper Limb Lymphedema in...
    Sheila H. Ridner, Mary S. Dietrich, Jie Deng, Candace M. Bonner, Nancy Kidd
    Lymphatic Research and Biology
    Methods and Results: Using a standardized protocol, impedance ratios among healthy normal women, breast cancer survivors with lymphedema, and breast cancer survivors without ...

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