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  • Single-Use Mini Bioreactor
    for parallel operation of four, eight, or more mini-bioreactors, which is suited for design of experiment, bioprocess development screening, and for use as a scale-down model. ...
    5-15-2013
  • Fujifilm Builds Cell Banking and cGMP Manufacturing Facilities...
    It will initially offer 200 L and 1000 L single-use bioreactors, with 2000 L bioreactors already planned for 2014. "I am delighted that we have commissioned the cell bank facility ...
    4-22-2013
  • Single-Use Bioreactor Roundup
    Single-use bioreactors (SUB), in particular, are rapidly increasing in popularity and seem ... What are the biggest challenges for manufacturers of single-use bioreactors? Mr. Abellan: ...
    4-15-2013
  • Saccharification and Fermentation Bioreactor
    Infors HT Rittergasse 27 SWITZERLAND CH-4103 INFORS HT is your specialist for bioreactors, incubation shakers and bioprocess control software. You benefit from sophisticated ...
    4-15-2013
  • Media's Role in Cell Culture Success
    ... them through a process Pall's Smith describes as "an input/output problem that is almost like live biofeedback control, with the bioreactors behaving like a living organism." ...
    4-1-2013
  • Shake-Flask Feedback Controlled Feeding
    ... the shake-flask cultures reached lower output in cell dry weight and product concentration ( Figures 3A-B ), which is caused by the higher oxygen transfer capacity of bioreactors. ...
    4-1-2013
  • Medicine: Getting Personal
    ... a single batch, with the goal of moving toward bioreactors for large-scale manufacturing. ... of adherent cells to bioreactors and the use of microcarriers to increase cell yields. ...
    3-15-2013
  • Sartorius Boosts PAT Portfolio with Advanced Biomass Sensor Technology
    SSB will manufacture the biomass sensors under a license, integrate these into its single-use bioreactors, and exclusively market these products in a dual-branding arrangement. New ...
    2-28-2013
  • Tying Up Loose Ends in Cell-Line Development
    ... The ambr 48 system uses disposable bioreactors with 10-15 mL working volume. The system ... to explore clone productivity in bioreactors prevented their use early in cell-line ...
    2-1-2013
  • Single-Use Systems Entice Multiple Users
    ... complexity often involved in hardware modifications on stainless steel bioreactors. ... According to Finesse, TruBio DV software can be used with glass vessels, wave bioreactors, ...
    1-15-2013
  • Technologies Evolving for Cellular Therapies
    ... The company is working on providing products for large-scale production of stem cells that customers can use in a validated environment. The primary focus is on bioreactors and ...
    1-15-2013
  • Scaling Up Stem Cells
    system Disposable bioreactors have recently appeared as a technology of choice for culturing cells at large scale. That said, most existing disposable bioreactors are efficient for ...
    1-15-2013
  • TAP Biosystems Partners with Life Tech on New Expression Platform
    The ambr system uses scale-down bioreactors where culture conditions such as pH and DO are controlled in 48 micro bioreactors (10-15 mL) in parallel. The goal is to ensure that ...
    1-15-2013
  • Reducing Biomanufacturing Bottlenecks
    Traditionally, approaches such as shake flasks and benchtop bioreactors have been used to ... The capacity for using benchtop bioreactors is especially limited as it is ...
    1-1-2013
  • Microcarriers for Bioprocess Scale-Up
    The microcarriers can simplify the scale-up of attachment-dependent cells by providing a premeasured, sterile, ready-to-use product for direct transfer into bioreactors. This ...
    1-1-2013
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    Journal Articles

  • Hepatic Differentiation of Human Embryonic Stem Cells Is Promoted...
    Toshio Miki, Alexander Ring, Jörg Gerlach
    Tissue Engineering, Part C: Methods
    3D perfusion culture to induce hepatic differentiation in hESC. Undifferentiated hESC were inoculated into hollow fiber-based 3D perfusion bioreactors with integral oxygenation. ...
  • Hepatic Maturation of Human Fetal Hepatocytes in Four-Compartment...
    Alexander Ring, Jörg Gerlach, Grant Peters, Benjamin J. Pazin, Crescenzio F. Minervini, Morris E. Turner, Robert L. Thompson, Fabio Triolo, Bruno Gridelli, Toshio Miki
    Tissue Engineering, Part C: Methods
    fiber-based three-dimensional (3D) perfusion culture system. hFH were isolated from 17- to 19-gestational-week livers and cultured in the 3D perfusion bioreactors for 14 days. ...
  • Improvement of Culture Conditions of Human Embryoid Bodies Using...
    Julien Côme, Xavier Nissan, Laetitia Aubry, Johana Tournois, Mathilde Girard, Anselme L. Perrier, Marc Peschanski, Michel Cailleret
    Tissue Engineering, Part C: Methods
    First, perfused STLV bioreactors were set up, to provide continuous delivery of culture ... Perfused and dialyzed STLV bioreactors promoted formation of embryoid bodies that were ...
  • Preparation of Ex Vivo -Based Biomaterials Using Convective Flow...
    Carolina Villegas Montoya, Peter S. McFetridge
    Tissue Engineering, Part C: Methods
    on orbital shaker plates, and convective flow run at 5, 50, and 150?mmHg within perfusion bioreactors. Extracted phospholipids and total soluble protein were assessed over time. ...

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