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  • Still a Place for Steel and Glass
    ... Most plastic bioprocess containers are sterilized at the manufacturer, and intended for ... is maintaining consistency in materials of construction as processes scale up. ...
    8-1-2013
  • Downstream Process Bottlenecks
    ... from the earliest development phases to ease scale-up efforts afterwards. It is now more or less a given that downstream bioprocess bottlenecks arise from rising upstream titers. ...
    7-1-2013
  • Separation of Therapeutic Biomolecules
    The program provided a balance of theory, practical applications, scale-up tools, and ... A columns to what Peter Hagwall, Ph.D., bioprocess product manager at GE Healthcare, ...
    5-1-2013
  • Media's Role in Cell Culture Success
    from clone selection to process development, scale-up, and commercial manufacturing. ... Shawn Smith, senior director, upstream bioprocess technologies at Pall Life Sciences. ...
    4-1-2013
  • Shake-Flask Feedback Controlled Feeding
    Online Measurement of DO with Chemical Optical Sensors In bioprocess development for the ... However, it is often difficult to determine critical parameters for scale-up of processes ...
    4-1-2013
  • Technologies Evolving for Cellular Therapies
    ... that can be used to facilitate the scale-up and industralization of stem cell ... new products and adapt existing bioprocess platforms, optimized for stem cell production. ...
    1-15-2013
  • Reducing Biomanufacturing Bottlenecks
    and optimization of new recombinant clones is a key step in early bioprocess development. ... These clones often perform as expected in scale-up, but scientists are never certain if ...
    1-1-2013
  • Microcarriers for Bioprocess Scale-Up
    A new line of microcarriers for large-scale vaccine and cell therapy manufacturing is now available. The microcarriers can simplify the scale-up of attachment-dependent cells by ...
    1-1-2013
  • Systems Biology Tackles Range of Challenges
    director of the centre of bioprocess engineering at the University of Stuttgart, Germany. ... ATPS combines high biocompatibility and selectivity with easy and reliable scale up, and ...
    12-1-2012
  • Self-Cleaning Benchtop Bioreactor
    HT is your specialist for bioreactors, incubation shakers and bioprocess control software. ... development/process optimization, process analytical technology, and scale-down/scale-up.
    12-1-2012
  • Confronting Scaleup Challenges Head On
    ... Scaling Productivity at Similar Scale At times bioprocessors seek to scale up productivity ... senior process science fellow, Gibco® PD-Direct Bioprocess Services, Life Technologies. ...
    10-15-2012
  • Up- and Downstream Go Single Use
    They gradually moved into the heart of the bioprocess stream with the emergence of ... disposable flow paths for process scale-up and production for early clinical ...
    10-1-2012
  • Advertorial: Asahi Kasei Bioprocess
    manufacturing and R&D. Asahi Kasei Bioprocess Europe in Belgium and Germany ... Process scale-up is simplified because Planova filters are available in surface area sizes ...
    10-1-2012
  • Acquisitions Grow Corning's Product Line
    ... products play an important role in bioprocessing and scale-up operations," he notes. ... When complete, the acquisition will expand offerings in drug discovery tools, bioprocess ...
    9-15-2012
  • Small-Scale Modeling and Predicting
    Optimizing production efficiency of a bioprocess to yield high titers of a desired ... of a small-scale process right on through scale-up to industrial-scale manufacturing. ...
    4-1-2012
  • Journal Articles

  • Establishing a Dynamic Process for the Formation, Propagation...
    Galia Yirme, Michal Amit, Ilana Laevsky, Sivan Osenberg, Joseph Itskovitz-Eldor
    Stem Cells and Development
    on the availability of a controllable bioprocess for their expansion and differentiation. We describe here a robust and well-defined scale up platform for human embryoid body (EB) ...
  • Bioprocess Development for Mass Production of Size-Controlled...
    Saeed Abbasalizadeh, Mehran Rezaei Larijani, Azam Samadian, Hossein Baharvand
    Tissue Engineering, Part C: Methods
    This novel bioprocess utilizes the stepwise optimization of both static and dynamic ... passaging in dynamic conditions, the scale-up from a static to a dynamic suspension ...

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