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  • Gene by Gene Acquires GE-Backed Arpeggi
    Myriad Genetics' patent claims for breast cancer susceptibility genes BRCA1 and BRCA2 . ... Myriad claimed the companies had infringed 10 patents associated with BRCA1 and BRCA2 that ...
    8-7-2013
  • New Gene Patent Suit Sparks Talk of Trolls
    they infringed 10 patents associated with BRCA1 and BRCA2 that were not covered by the ... of a basic fact of human biology-that the BRCA1 and BRCA2 genes are linked to breast ...
    7-23-2013
  • A Chemist's View of the Supreme Court's Gene Patent Decision
    Myriad was granted patents claiming, inter alia, "an isolated DNA coding for a BRCA1 ... Myriad's invention is not just the discovery of the location and sequence of the BRCA1 and ...
    7-18-2013
  • Myriad Sues Ambry, Gene by Gene Amid Confusion Over Supreme Court...
    related to screening for the BRCA1 and BRCA2 genes after the June 13 ruling was made. ... in patents covering synthetic DNA and methods-of-use related to the BRCA1 and BRCA2 genes. ...
    7-11-2013
  • Myriad to Perform BRCA Testing in CDx Deal with Tesaro
    company Tesaro to conduct BRCA1 and BRCA2 mutation testing on patients to ... test, which can be used to detect BRCA1 or BRCA2 mutations, will be used as a ...
    6-25-2013
  • A Myriad of Winners
    ... Insight(SM) test, which will also be competitively priced, spokesperson Terri Somers told GEN. Pathway is but one firm making such claims related to BRCA1/2 testing. Case Closed? ...
    6-17-2013
  • Advertorial: Profiling Breast Cancer Variants
    ... Using the "grep" function, specific genes can be searched within the variant function file. For example, high breast cancer risk genes such as TP53, BRCA1 and BRCA2 are searched ( ...
    6-15-2013
  • Supreme Court Upends Patentability of Genes, but Not cDNA
    ... any genetic information encoded in the BRCA1 and BRCA2 genes, but instead uncovered the ... searching for the BRCA1 and BRCA2 genes, it could possibly have sought a method patent. ...
    6-13-2013
  • Study: Genetic Testing Uptake within Cancer-Affected Families...
    for breast and ovarian cancer-associated BRCA1 and BRCA2, the same could not be said for ... finding an increase in testing for BRCA1/2 from 2,095 a year in 2003 to 7,393 in ...
    6-10-2013
  • Patent Eligibility of Biological Methods and Compositions
    ... of detecting a germline alteration in the BRCA1 gene or screening a tumor sample that ... a transformed eukaryotic host cell containing an altered BRCA1 gene causing cancer. ...
    6-3-2013
  • The Price of BRCA Testing
    after testing positive for the BRCA1 gene, she opted to have a double mastectomy to reduce her chances of getting breast cancer. As tests for BRCA1/2 currently cost thousands of ...
    5-21-2013
  • Crowdfunding Touches Down in Biotech
    ... The research entails treating male BRCA1+/- heterozygous mutant mice with a PARP inhibitor ... Mice pups will be genotyped to determine whether PARP led to fewer BRCA1 mutant carrier ...
    5-15-2013
  • Companion Diagnostics: 52 Pick-Up
    ... Myriad Genetics and Teva Pharmaceutical (Cephalon) Agreement announced March 28, 2012 Collaboration to test for BRCA1 and BRCA2 mutation via Myriad's lead product, BRACAnalysis® ...
    5-9-2013
  • Two Roads to Wowing the Crowd
    ... The research entails treating male BRCA1+/- heterozygous mutant mice with PARP (olaparib) ... Mice pups will be pups will be genotyped to determine whether PARP led to fewer BRCA1 ...
    4-16-2013
  • Major Advance: Novel DNA Cancer-Associated Variants Identified
    ... breast cancer, which correlates in most cases with mutations in the BRCA1 and BRCA2 genes. ... aim is to study ovarian cancer; and CIMBA, which studies BRCA1 and BRCA2 modifications. ...
    3-28-2013
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    Journal Articles

  • Genetic Testing for BRCA1 and BRCA2 : Recommendations of the...
    BARBARA A. KOENIG, HENRY T. GREELY, LAURA M. McCONNELL, HEATHER L. SILVERBERG, THOMAS A. RAFFIN
    Journal of Women's Health
    Genetic Testing for BRCA1 and BRCA2 : Recommendations of the Stanford Program in Genomics, Ethics, and Society Journal of Women's Health
  • VCP, a Weak ATPase Involved in Multiple Cellular Events, Interacts...
    Hongtao Zhang, Qiang Wang, Kiichi Kajino, Mark I. Greene
    DNA and Cell Biology
    VCP, a Weak ATPase Involved in Multiple Cellular Events, Interacts Physically with BRCA1 in the Nucleus of Living Cells DNA and Cell Biology
  • BRCA1-Mediated Ubiquitination Inhibits Topoisomerase II α Activity...
    Hirokuni Shinagawa, Yoshio Miki, Kiyotsugu Yoshida
    Antioxidants & Redox Signaling
    BRCA1-Mediated Ubiquitination Inhibits Topoisomerase II α Activity in Response to Oxidative Stress Antioxidants & Redox Signaling
  • Influences of Multiple Genetic Polymorphisms on Ovarian Cancer...
    Sharmila Velapasamy, Livy Alex, Jagdish Kaur Chahil, Say Hean Lye, Khamsigan Munretnam, Nikman Adli Nor Hashim, Nurul Hanis Ramzi, Noraihan Mohd Nordin, Vicknesh Visvalingam, Lian Wee Ler
    Genetic Testing and Molecular Biomarkers
    Risk assessment, however, can only be accomplished if the risk factors are known. To date, the genetic risk factors for ovarian cancer, other than mutations in the BRCA1/2 genes, ...

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