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Search Results - Antigen
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  • Hematologic Diagnostics Go with the Flow
    ... In his study, Keeney examined antigen expression in the remission state-i.e., 29 days after therapy initiation-in order to quantify residual tumor cells. He noted that minimal ...
    8-1-2013
  • PharmAthene, Theraclone Agree to Merger
    anthrax antitoxin; and PharmAthene's SparVax®, a recombinant protective antigen (rPA), next-generation anthrax vaccine for pre and post-exposure prophylaxis of anthrax infection. ...
    8-1-2013
  • Life Tech Licenses Dynabeads to Novartis, with Cancer Therapy...
    therapeutic T cells to express chimeric antigen receptors for treating cancer-the first ... property exclusively toward chimeric antigen receptors for cancer treatment. "The ...
    8-1-2013
  • Molecular Imaging Driving Development
    ... Using fluorescence-labeled antibodies targeting a tumor-associated surface antigen, accumulation in tumor tissue can be accomplished within six to 24 hours post-injection. As such, ...
    8-1-2013
  • Membrane Protein Monoclonal Antibodies
    ... recognize membrane-dependent protein antigen structures that are large enough to ... specificities. The intrinsically gentle antigen delivery process of DNA immunization may ...
    8-1-2013
  • NIAID Grants MBio $1.4M to Develop POC HIV Diagnostic
    a low-cost, point-of-care (POC) HIV antigen/antibody combination diagnostic device. ... According to MBio, its HIV antigen and antibody assays provided a combined performance ...
    7-22-2013
  • Drug Candidates on Trial
    ... Patients will be evaluated for safety, prostate specific antigen response, progression-free survival, and reduction in circulating tumor cells. > VentiRx Pharmaceuticals initiated ...
    7-22-2013
  • A Chemist's View of the Supreme Court's Gene Patent Decision
    ... For example, if the "information" in an antibody is its antigen-binding specificity, then any antibody fragment that retains the same antigen-binding specificity would be patent ...
    7-18-2013
  • Long-Term Microbiome Studies Illuminate Gut Bugs' Roles in Health...
    can establish a structurally balanced architecture of gut microbiota that may exert a health benefit to the host via reduction of antigen load from the gut," Dr. Zhao et al. write. ...
    7-15-2013
  • ADC, BZL Aim Warheads at PSMA-Positive Prostate Cancers
    PSMA is a cell-surface antigen on prostate cancer cells, and PSMA levels correlate directly with an aggressive, metastasizing phenotype. The firms claim that the characteristics of ...
    7-15-2013
  • Top 15 Vaccines of 2012
    ... Approved for use as a three-dose series in infants born of hepatitis B surface antigen (HBsAg)-negative mothers; may be given as early as six weeks of age through six years of age ...
    7-2-2013
  • 4 Steps to Get Your ChIP Experiment Working
    Read on and discover four steps to take your ChIP expertise to the next level: Cross-linking or not? The aim of cross-linking is to fix the antigen of interest to its chromatin ...
    7-2-2013
  • HTRF Applications in New Drug Discovery
    HTRF is based on a pair of specific donor and acceptor dyes which, once coupled to interacting partners (e.g., antibody-antigen, ligand-receptor, etc.), and when brought in close ...
    7-1-2013
  • Shutting Off the Immune Attack that Causes Type 1 Diabetes
    For this study, the investigators said they attempted to modulate, in an antigen-specific ... to proinsulin, with no effect on other antigen-specific T cell responses, also occurred. ...
    6-25-2013
  • Lophius Wins $469K to Develop MS Diagnostic
    technology, which unlike current diagnostic methods exploits the maturation processes induced in antigen-presenting cells through interaction with activated T helper (Th) cells. ...
    6-19-2013
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    Journal Articles

  • Safety and Efficacy of a Genetic Vaccine targeting Telomerase...
    Alessandra Gavazza, George Lubas, Arthur Fridman, Daniela Peruzzi, Joseph A Impellizeri, Laura Luberto, Emanuele Marra, Giuseppe Roscilli, Gennaro Ciliberto, Luigi Aurisicchio
    Human Gene Therapy and Part B: Methods
    immune responses against this tumor antigen and increase overall survival of dogs ... number of LSA patients, measured the antigen-specific immune response and evaluated ...
  • Effect of Trichinella spiralis Infection on the Immune Response...
    Fei Guan, Xiao Hou, Ge Nie, Yan Xiao, Qi Zhang, Wen-qi Liu, Yong-long Li, Jia-hui Lei
    Foodborne Pathogens and Disease
    This study demonstrated that the enteric stage of T. spiralis infection could inhibit the proliferative response of spleen lymphocytes to hepatitis surface antigen (HBsAg) and lead ...
  • Regimen specific effects of RNA-modified chimeric antigen receptor...
    David Maxwell Barrett, Xiaojun Liu, Shuguang Jiang, Carl H June, Stephan A Grupp, Yangbing Zhao
    Human Gene Therapy and Part B: Methods
    chimeric antigen receptor T cells in mice with advanced leukemia Human Gene Therapy and Part B: Methods Cytotoxic T lymphocytes (CTLs) modified with chimeric antigen receptors ...
  • Radiation-associated small cell neuroendocrine carcinoma of the...
    Zhanna Mussazhanova, Shiro Miura, Boban Stanojevic, Tatiana Rogounovitch, Toshio Shiraishi, Tomomi Kurashige, Kazuko Shichijo, Kenichi Kaneko, Haruo Takahashi, Masahiro Ito, Masahiro Nakashima
    Thyroid
    were strongly positive for neuroendocrine markers and thyroglobulin (Tg), a marker of thyroid follicular cells, but negative for calcitonin and carcinoembryonic antigen (CEA). ...

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