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Nov 4 2009, 11:16 AM EST

Pfizer Licenses Flamel’s Platform to Develop Controlled-Release Protein Therapeutic Formulations for $1M

GEN News Highlights

Pfizer exercised its option to license Flamel Technologies’ Medusa® platform to develop a controlled-release (CR) formulation of an already-marketed therapeutic protein. The decision triggered a $1 million fee to Flamel, as per an agreement between Flamel and Wyeth.

In January Pfizer offered to pay $68 billion for Wyeth. The acquisition successfully closed last month.

Pfizer will take over Wyeth’s responsibilities under its deal with Flamel, paying all development costs, milestone fees, and royalties on worldwide sales. The alliance was formed in 2007 to evaluate Medusa’s ability to create CR formulations of therapeutic proteins for intravenous administration. 

The Medusa technology is designed to deliver CR formulations of proteins, peptides, other large molecules, as well as small molecules. The platform is being applied to improve its partners’ already-marketed and novel biologics with respect to safety, efficacy, and pharmacokinetics. Flamel reports that Medusa also offers solutions to threshold issues such as aggregation and solubility.

 

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Related News
Pfizer Taps Xencor for Antibody-Optimizing Technology (Mar. 2, 2009)
Merck Serono Licenses Flamel Technology for Roughly $6.3M (Feb. 17, 2009)
Ambrx and Wyeth Sign Multitarget Alliance to Develop Protein Drugs (Sep. 18, 2009)
Cyclogenix Inks License and Research Deals Wyeth and IMBcom to Further Peptide Research (Feb. 26, 2009)
Pfizer to Pony Up $68B for Wyeth (Jan. 26, 2009)

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