Jun 18 2008, 7:08 PM EST
News source: Business Wire
MitoSciences has today released two new products for measuring
Mitochondrial Biogenesis, a crucial biological process that is
receiving increased attention due to its link to increased life span
and greater resistance to disease.
Mitochondrial Biogenesis is at the center of highly-publicized
recent studies describing the positive effects of resveratrol (the
healthful component in red wine and an activator of proteins called
sirtuins) and the creation of the so-called Super Mouse.
The other side of Mitochondrial Biogenesis involves negative
effects, and pharmaceutical companies have recognized for years that
antibiotic and antiviral drugs can significantly inhibit Mitochondrial
Biogenesis. Developers of drugs for HIV patients are particularly
aware of such effects, but methods for rapidly evaluating the toxic
effects of HIV drugs on patients have been limited.
MitoSciences is offering two new solutions to researchers with the
release of the MitoProfile(R) Biogenesis kits. The MS631
MitoProfile(R) Biogenesis Dipstick Kit is designed for point-of-care
testing, and the MS641 MitoProfile(R) Biogenesis Microplate Kit is
designed for high-throughput analysis.
"Our hope is that these new kits will provide useful tools to
support some very promising areas of disease prevention research,"
said Jean-Paul Audette, president of MitoSciences, "while also
supporting ongoing research into the best and safest ways to
administer antiviral and antibiotic drugs."
Both tests are highly sensitive, while also being faster, easier,
and less expensive than existing methods for evaluating Mitochondrial
Biogenesis. Both kits are for research use only, not for diagnostic
testing, although the Biogenesis Dipstick Kit has been approved by the
FDA For Investigational Use Only, a designation for tests that are
undergoing clinical validation.
Also released today were several new products for studying
apoptosis and Friedreich's Ataxia (the most common form of inherited
ataxia):
- MSF41 Microplate Assay Kit for Frataxin is a quantitative assay
for measuring frataxin, a protein that is decreased in Friedreich's
Ataxia (FA) patients. This kit is a high-throughput complement to the
existing Dipstick Kit for Frataxin (MSF31), and is particularly suited
to drug developers working on FA therapies.
- MSF42 Recombinant Human Frataxin provides very useful control
material to users of both MSF31 and MSF41 for use in generating
standard curves.
- MSA42 Microplate Assay Kit for Apoptosis-Inducing Factor (AIF)
is a high-throughput complement to the existing MSA31 Dipstick Assay
Kit for AIF, providing another tool for analyzing AIF's role in
apoptosis, oxidative stress, and Complex I assembly.
About MitoSciences Inc.
MitoSciences is a developer and manufacturer of monoclonal
antibodies and immunoassays for use in understanding mitochondrial
function and metabolism. MitoSciences' products are used by
pharmaceutical companies, clinical laboratories, and basic researchers
to unlock the role of metabolic enzymes in disease, drug therapy, and
drug toxicology. With an emphasis on developing assays that can
measure multiple parameters in a single sample, MitoSciences is
supporting the rapidly growing fields of systems biology and
personalized medicine.
Links
http://www.mitosciences.com
ADVERTISEMENT
INTERVIEW:
NEW PROGNOSTIC GENETIC TEST FOR ADOLESCENT SCOLIOSIS - Interview with Dr. Baron Lonner, director of Scoliosis and Spine Associates
...MORE
NewsArticles BlogsADVERTISEMENT
Subscribe to RSS
Email
Print
Share
More News
Listen
Save
Comment
View All