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Aug 7 2007, 12:30 AM EST

Arpida Presents a Large Body of Preclinical and Clinical Data at Scientific Conferences

PRNEWSWIRE

REINACH and BASEL, Switzerland, August 7 /PRNewswire-FirstCall/ -- Arpida Ltd. (SWX: ARPN) announced today that it will be presenting a large volume of data on iclaprim at the upcoming Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) on 17 - 20 September 2007 in Chicago and at the annual meeting of the Infectious Diseases Society of America (IDSA) on 4 -7 October in San Diego. Furthermore, data on AR-709 and AR-2474 will be presented at ICAAC.

ICAAC and IDSA are major scientific conferences where thousands of scientists and physicians gather to discuss the latest developments in their respective areas. A total of 37 posters have been accepted at these conferences. Additional information can be found on the conference websites.

    The following 19 abstracts on iclaprim have been accepted by ICAAC.

    Nr.  Author      Title
    630  Koeth       The Effect of Testing Parameter Variations on the In
                     Vitro Activity of Iclaprim against Staphylococcus aureus

    736  Mason       In Vitro Activity of Iclaprim against Community-Acquired
                     and Nosocomial Clinical Isolates of Staphylococcus
                     aureus

    737  Cevenini    In Vitro Activity of Iclaprim and Comparators against
                     Chlamydia trachomatis

    1073 Aranza      Iclaprim (ICL) Defined Quality Control (QC) Limits for
                     MIC and Disk Diffusion (DD) Susceptibility Testing
                     According to CLSI M23-A2 Procedures

    1342 Brandt      Pharmacokinetics and Bioavailability of Iclaprim Oral
                     and Intravenous Formulations in Humans

    1487 Brandt      Absorption, Pharmacokinetics, Metabolism and Excretion
                     of Iclaprim in Healthy Humans

    1491 Brandt      Pharmacokinetics and Metabolism of [14C]Iclaprim in the
                     Marmoset

    1499 Brandt      Interactions of Iclaprim with Human Cytochrome P450
                     Enzymes

    1502 Brandt      Tolerability and Pharmacokinetics of Single and Repeat
                     Ascending Doses of Iclaprim in Healthy Adults

    1545 Murphy      Comparative Efficacy of Iclaprim (ICL) against Wild-Type
                     and Thymidine Kinase-Deficient S. aureus in a Mouse
                     Protection Model

    1574 Jones       Bactericidal Activity and Post-Antibiotic Effect of
                     Iclaprim (ICL) against Staphylococcus aureus (SA)

    1667 Brown       In Vitro Activity of Iclaprim against Clinical Isolates
                     of Legionella pneumophila

    1923 Engelhardt  Comparative Evaluation of Iclaprim (ICL) MIC Testing
                     with Etest and CLSI Reference Methods

    1971 Sader       In Vitro Activity of Iclaprim and Comparison Agents
                     Tested against Neisseria gonorrhoeae Including Growth
                     Stimulating Effects

    1985 Sader       Antimicrobial Activity of a Novel Dihydrofolate
                     Reductase, Iclaprim, Tested against Clinical Strains of
                     Enterobacteriaceae (ENT): Results from the International
                     Study of Iclaprim Susceptibility (ISIS)

    1991 Hadvary     Microbiological Efficacy of Iclaprim against
                     Staphylococcus aureus in Complicated Skin and Skin
                     Structure Infection (cSSSI): Preliminary Results of
                     ASSIST-1

    2000 Sader       Comparative Evaluation of Iclaprim Potency and
                     Bactericidal Activity Tested against Enterococci:
                     Results from the International Study of Iclaprim
                     Susceptibility (ISIS)

    2016 Sader       In Vitro Activity of Iclaprim, a Novel
                     Diaminopyrimidine,Tested against beta-Haemolytic
                     S



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