Designed for pilot-, clinical-, and commercial-scale manufacturing of biopharmaceuticals, the Planova™ Virus Filtration Controller can perform consistent virus removal using Planova and Planova BioEX filters. Customary virus filtration operations coupled with integrated vertical Visual Leak Testing (vVLT) and automation can increase functionality and enable the Virus Filtration Controller to accommodate pressurized feeds and feeds from single-use bags.