Designed to transfect primary and hard-to-transfect cells, Magnetofectamine™ is the combination of Lipofectamine™ 2000, a transfection reagent from Life Technologies (Invitrogen™) for nucleic acid delivery (DNA and siRNA), with the Magnetofection™ based reagent CombiMag. Magnetofection is a method of transfecting cells in vitro and in vivo. Magnetic force allows a rapid concentration of genetic material onto cells and promotes cellular uptake. In the presence of CombiMag reagent, Lipofectamine 2000 delivers DNA at higher efficiencies, from +30 to 500%. With Magnetofectamine, up to 75% transfection efficiencies can be achieved into many primary cells such as endothelial, chondrocytes, epithelial, and human mesenchymal stem cells.